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COVID-19 Host Genetics Initiative Profile picture
COVID-19 Host Genetics Initiative
@covid19_hgi
The COVID-19 host genetics initiative brings together the human genetics community to learn the genetic determinants of COVID-19 susceptibility and outcomes
Jul 8, 2021 • 9 tweets • 5 min read
Today we are thrilled to announce the #COVID19 HGI manuscript is published @Nature nature.com/articles/s4158…

In this study, we report that the human genome significantly contributes to an individual’s response to SARS-CoV-2 infection.
1/ Leveraging data from ~50,000 COVID-19 patients & 2 million uninfected controls, we report 13 loci associated with SARS-CoV-2 infection or COVID-19 disease.
Some loci associate with the likelihood of getting infected & a distinct set of loci associate with disease progression.
2/
Mar 12, 2021 • 12 tweets • 6 min read
Our @covid19_hgi flagship paper is OUT NOW on medrxiv!

medrxiv.org/content/10.110…

In numbers:
50,000 SARS-COV-2 patients
46 participating studies
19 countries represented
15 loci identified
2,870 authors

#Covid19 #Genetics #Sarscov2 #immunology #scicomm #DNA Our study objective was to form a global network of investigators to identify genetic factors influencing SARS-COV-2 infection and severe manifestations of COVID-19.