In the midst of all the grief + chaos of 2020, it's hard to remember there were good things
For me, an incredible group of young scholars doing highly relevant science was the #Bestof2020. Here are my favorite 2020 paper by each of several young scholars with whom I get to work
To see where some of these folks were last year see this thread
The time of night sucks. The need to learn + responsibility to teach are still there. I am proud of how our fellows consistently rise to meet the challenge
Effect of Pressure Support vs Unassisted Breathing Through a Tracheostomy Collar on Weaning Duration in Patients Requiring Prolonged Mechanical Ventilation via @JAMA_current
This proposed “do + report back” is literally the definition of research — changing care of a patient to create generalizable knowledge rather than focused on that specific patient—and is frankly unethical and probably illegal
#HardPass unless there is informed consent involved
Because this involves me being in a twitter fight with someone I deeply respect, let me be a little clearer
Mar 28, 2020 • 22 tweets • 6 min read
The initial logic behind using a single #ventilator to support #multiple#patients is compelling, and speaks to our most basic urge to rescue.
A long thread, to outline challenges that must be solved for it to work in #COVID19
There are certain situations in which it would work well – in patients with fundamentally normal lungs, whose compliance can be easily matched and kept matched, who can be deeply neuromuscularly paralyzed, and ...
Here are my slides to give you a sense of what the conversation may be about. Join us!
Mark Mikkelsen and I have been deeply influenced by Creditor's classic article ncbi.nlm.nih.gov/pubmed/8417639
These graphics hopefully forthcoming from Oxford Textbook of Medicine edited by @icuresearch
Starting in the unit for 14 days tomorrow. The fellows + I are going to try to do 1 new paper a day to catch up, just a conversation with more senior trainees + attendings, with space for lots of assumed knowledge
Here's our prelim list if you want to read along...
#ICUreadings
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome and Posterior Probability of Mortality Benefit in a Post Hoc Bayesian Analysis of a Randomized Clinical Trial jamanetwork.com/journals/jama/…
Optimal Duration of Time-Limited Trials in Critically Ill Patients
"If they are going to respond to this, we should see a response by ..."
What are median + 95th percentile for responses to common life-saving therapies?
I feel like we "know" this for lots of small things
- Lasix should make 'em pee within 20 minutes
- PEEP improves oxygenation in 20 minutes
- uroseptic shock should break within 24 hour