Jeremy Kamil Profile picture
Virologist, Associate Professor @LSUHS. I study human cytomegalovirus. (he, him). Opinions my own, not my employer's. #LoveVirology
10 Apr
This article by @davidhth is excellent and he is a super talented reporter but people in @CDCgov OAMD & beyond spread falsehoods about @GISAID.. and if you look closely can see it in the reporting here & elsewhere.. usatoday.com/in-depth/news/…
Beware of agendas. BIG DATA on pathogen genome sequences is VALUABLE. There are organized whisper campaigns to smear and distort.
GISAID is the first example of a system that incentivizes real time sharing of pathogen sequence data across borders.
Read 9 tweets
9 Apr
Your Forbes piece plus the explanatory cartoon by @malki form an effective vaccine that stops sealions in their tracks..
Because just like the adaptive immune system, early recognition is the best defense.
For example .. this is the Marshall sea lion-001 vaccine in action
Read 4 tweets
9 Apr
Had a great phone call with this Richard Neher guy.. sometimes a bit of Twitter theatre 🎭 can lead somewhere good!
..@nextstrain (Auspice + Augur) and @GISAID (EpiFlu + EpiCoV) have worked together to revolutionize how we understand outbreaks and have led to virtuous cycles of enhanced genome sequencing around the world 🌍
There are great things in store for all of us when we each get past our disagreements and/ or misunderstandings...
Read 4 tweets
8 Apr
Reimbursed? This says a lot about your respect or lack thereof for our intellectual contributions. Thanks!
Should @Tuliodna and @houzhou be “reimbursed” for “filling the void,” too.. and discovering B.1.351 and many other emergent variants? Is that our role? A raw materials producers those like you who refine pretty phylogenetic trees?
Or maybe local virologists want to engage with their local & international collaborators like @VirusWhisperer to develop viral neutralization assays?
Read 8 tweets
8 Apr
Our efforts are significant, too. SIGNIFICANT FOR PUBLIC HEALTH. You and your office has funded 0️⃣ of them.
Francis Collins discussed our work (positively) with the Washington Post.. and your boss, Greg Armstrong, presented to on the Q677 variants we helped discover
But we have seen no direct support from @CDCgov @CDCemergency @CDCDirector ... instead you take Louisiana $$$ and send it to @Labcorp & Quest & Illumina and stamp your name as SENIOR AUTHOR every time they publish a sequence under the CDC contracts you cut for them.
Read 4 tweets
7 Apr
Sequencing pathogens & sharing the data is a public health utility. It needs to be distributed and decentralized to avoid the next COVID-19. And also, let’s face it.. to modernize how we move forward against all community transmitted infectious diseases.
Academia has huge role in community outreach, education & microbial genomic surveillance. CDC OAMD support for this has been ALL TALK. NO WALK.
Read 8 tweets
7 Apr
“It’s not for lack of trying” ????
IT IS FOR LACK OF TRYING.
nature.com/articles/d4158…
We have sequenced ~60% of all Louisiana SARS-CoV-2 since beginning of pandemic. No funds from CDC... no serious discussions with contracting officials. Just talk talk talk talk talk. tick toc...
..@tylercowen & COVID-19 fast grants came through while @dmaccannell busy giving your tax dollars directly to @illumina @Labcorp etc who hadn’t even “ramped up” yet sciencemag.org/news/2021/02/u… Image
Read 6 tweets
7 Apr
In the near future, ongoing community-based surveillance sequencing will release daily / weekly reports on the viruses 🦠 and bacteria that are actively causing illnesses in our schools, workplaces, care homes, et cetera Image
This is the future of global health.. and it will be happening in all countries, rich and poor.. cc: @WHO @RockefellerFdn @RickABright @GISAID @AfricaCDC @PardisSabeti
The technology is here but a few challenges remain.. we need to make sure to build trust in communities & be transparent about what we are doing when we obtain samples from communities
Read 8 tweets
7 Apr
Always happy to amplify 🧬 @MiGScenter .. Pun Intended! they’ve done heroically excellent —and frankly, under recognized— SARS-CoV-2 🦠 sequencing during the pandemic.
I’d also add that @vscooper and Dan Snyder not only run @MiGScenter but ALSO took time to provide top notch advice to help @LSUHSEVTLab get its sequencing off the ground.. and to collaborate with us..
Read 5 tweets
7 Apr
Even though SARS-CoV-2 🦠 🧬 sequences from the entire continents of Africa 🌍 + South America make up only ~25K of the 1M genomes on @GISAID.. the work of their scientists has had a HUGE IMPACT ⚡️ 💥
In fact, these incredibly talented researchers from places like @krisp_news & @fiocruz_en, eg @houzhou @Tuliodna @fnaveca @PaolaResende1 DISCOVERED 2 of the 3 @WHO designated Variants of Concern!
Read 4 tweets
7 Apr
👩🏽‍🔬 Sharing resources with our communities to defeat spread of infectious disease in real time. nytimes.com/2021/03/24/hea…
We now have testing + sequencing 💪🏼 + technology + talent to test, trace, predict, vaccinate, and/or treat or defeat a vast many different COSTLY viral diseases and antibiotic-resistant bacterial infections.
Science and technology are ready to deploy globally 🌍. And will fuel a wave of outreach, education, not to mention save countless lives. But do we have the will and the right ideas to make it a reality?
Read 9 tweets
6 Apr
Think Global. Sequence 🧬 🦠 Local!
When you take a sample from a patient or a community, treat them like your intellectual equals.
Show respect ✊🏼 for your fellow human beings.. regardless of their income, religion, educational level, or political beliefs.
Read 5 tweets
6 Apr
As much as I applaud Gamaleya for developing an efficacious vaccine, this tweet and the associated links are not a scientifically accurate characterization of our findings (to be as diplomatic as I know how).
..@EricTopol does a much more ACCURATE job summarizing our findings
This piece by Politico gets into the dangers of a pharmaceutical company account putzing around in false claims on social media. politico.eu/article/russia…
Read 6 tweets
6 Apr
This just means a lot of “those surveyed” don’t know what they are talking about.
Also.. gonna leave this here. It’s written by people who DO know what they are talking about. nature.com/articles/s4157…
Read 4 tweets
6 Apr
Gonna leave this right here.. @GISAID now at >1,000,000 SARS-CoV-2 sequences. This is the power of international collaboration among a community built on the trust needed to share data in real-time
GISAID is the envy of little would-be fiefdom makers who would seek to divide & conquer how We the People share genetic data on viruses that make us sick ...
These viruses and microbes are fascinating to study but can demolish our economies as much as they can rip apart the health and well being of an individual human being..
Read 23 tweets
6 Apr
I will continue to emphasize that Gamaleya Institute's Sputnik V vaccine is excellent! For example, Sputnik V sera neutralized the B.1.1.7 variant very effectively.
Despite the neutralization escape we observed with B.1.351 Spike, this vaccine will save many hundreds or even thousands of lives worldwide! medrxiv.org/content/10.110…
Read 9 tweets
5 Apr
Topic du Jour: #Sealioning 🦭
Now for an unabridged presentation of @malki’s ESSENTIAL @wondermarkfeed
h/t @DrShepherd2013 & wondermark.com/1k62/
here we go..
Read 8 tweets
5 Apr
🦭 “I raised a reasonable question...”
Read 4 tweets
2 Apr
Our latest work with @VirusWhisperer shows that the B.1.351 variant easily escapes Sputnik V vaccine elicited neutralizing antibodies. medrxiv.org/content/10.110…
Benhur’s data analyses are 👨🏽‍🍳’s 😘 .. and the amount of escape is just 👀 🤯
The system used here is a REPLICATION COMPETENT recombinant VSV carrying the SARS-CoV-2 Spike (or Spike from variants).. similar to systems used by @PaulBieniasz @ChandranLab @vsv512
Read 12 tweets
2 Apr
Re-reading this amazing @specterm piece from 2007 featuring @HarmitMalik @ArisKatzourakis @PaulBieniasz @memerman.. behind the scenes is Matt Stremlau's then recent discovery of TRIM5alpha, a factor that "restricts" certain retroviruses newyorker.com/magazine/2007/…
it's a favorite article of mine.. In fact, I always try to wheedle the medical students into reading it when I lecture on viral pathogenesis..and it's funny to realize it must have been some years since I read it in full.
so much admiration for the incredible journeys of imagination, curiosity, and hard work that goes into solving these riddles..
Read 7 tweets
2 Apr
😡. Dr. Heguy has been working tirelessly to serve the viral genomic surveillance needs of New Yorkers since beginning of the pandemic.
She’s one of the best in the world at sequencing & genomics. Her important work has been covered by @carlzimmer. nytimes.com/2020/04/08/sci…
She works at an academic medical center rooted in the NYC community. Yet @nycHealthy finds a way to spend New Yorker’s money contracting with a for-profit outfit instead of working with people like and her team @nyulangone or another at @IcahnMountSinai
Read 5 tweets