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To conclude the hypoglycemia debate at #HotTopicsNeo2019: Jane Harding of @AucklandUni and @AucklandLiggins. Do you have a @Wikipedia page? She does en.wikipedia.org/wiki/Jane_Hard… (!) @HotTopicsNeo
At what glucose threshold level should you treat? Harding transparent up front: I DONT KNOW. Not for lack of effort. CHYLD study published in @NEJM large prospective cohort w/continuous glucose monitoring. ncbi.nlm.nih.gov/pubmed/26465984
#HotTopicsNeo2019
CHLYD study unable to establish relationship between neonatal hypoglycemia (<47mg/dl) and NDI at 2 years. #HotTopicsNeo2019 #neoEBM
Follow up at 4.5 years suggestions possibility that more frequent or severe neonatal hypoglycemia a/w some, more specific, measures of cognitive function. In @JAMAPediatrics: ncbi.nlm.nih.gov/pubmed/26301959
#HotTopicsNeo2019 #neoEBM
2015 population based retro cohort study in @JAMAPediatrics suggests early transient hypoglycemia using traditional threshold of 47mg/dl a/w lower academic achievement at 10 years of age: ncbi.nlm.nih.gov/pubmed/26301959
#HotTopicsNeo2019 #neoEBM
Current hPOD study aims to know if use of prophylactic dextrose gel in at risk infants can help prevent hypoglycemia (YES! Recent results: 👇& journals.plos.org/plosmedicine/a…) and improve NDI (TBD, stayed tuned) #HotTopicsNeo2019 #neoEBM
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