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NEW Research—No evidence of benefit for #chloroquine and #hydroxychloroquine in #COVID19 patients, urgent randomised trials are needed: finding from a large observational study of nearly 15,000 patients with #COVID19 & 81,000 controls

Thread (1/4)
Study finds use of chloroquine or #hydroxychloroquine with or without a macrolide is linked to increased rates of mortality and heart arrhythmias among hospital patients with #COVID19 (2/4)
Authors suggest that these drug regimens should not be used to treat #COVID19 outside of clinical trials and urgent confirmation from randomised clinical trials is needed (3/4)
“The findings...add to preliminary reports suggesting that regimens of chloroquine or #hydroxychloroquine, alone or with azithromycin, are not useful & could be harmful in hospitalised patients with #COVID19” - Comment from C Funck-Brentano & J Salem (4/4)
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