Those Nerdy Girls Profile picture
Jun 8, 2020 8 tweets 4 min read Read on X
1/ Q: Should I get an #antibody test? Will it tell me if I’m immune and able to safely go about daily life?

A: Not yet. While antibody tests are improving rapidly, there are still too many fundamental challenges to using them to determine your *individual* exposure or immunity.
2/ Very briefly, antibody tests are (typically) blood tests that aim to measure previous exposure by testing for the presence of antibodies specific to #COVID19.
These are distinct from the PCR (nasal swab) tests that detect *current* presence of SARS-CoV-2 genetic material.
3/ There are three main limitations of antibody tests for personal use:
1) unknown immunity,
2) false positives, and
3) no clear direction for behavior change
4/
1) UNKNOWN IMMUNITY: Even for those who had #COVID, we don’t know the extent or duration of immunity conferred. The best current guess is protective immunity for at least 1-2 years. Still, previous exposure isn’t a scientific green light for lack of precautions.
5/
2) FALSE POSITIVES: Many positive antibody tests will be “false positives.” To see a worked example of why this is the case, I refer you to this nice explainer from COVIDexplained: explaincovid.org/post/understan…
6/
3) WHAT WOULD YOU DO WITH THIS INFO? For both of the reasons listed above, changing your behavior with regards to #coronavirus prevention, or protecting vulnerable family members after a positive antibody test, at this stage would be unwise.
7/ That being said, antibody tests are SUPER important in helping us develop evidence-based responses to #COVID__19 because they show us the "footprint" of the virus to date.
Here is a previous DP post that explains why:
facebook.com/dearpandemic/p…
8/ This article from @TheAtlantic gives a great overview of current issues around antibody testing:

theatlantic.com/health/archive…

And a useful review of PCR vs antibody testing:
explaincovid.org/post/testing/0…

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Those Nerdy Girls

Those Nerdy Girls Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @DearPandemic

Dec 22, 2022
How can I stay safe during the holidays?

➡️Think in terms of harm reduction. Don’t let the perfect be the enemy of the good.

dearpandemic.org/safe-holidays/

#covid #rsv #flu #HolidaysAreComing

1/
2/ Just in time for Christmas, #COVID is again on the rise.

#Flu and #RSV may be peaking—but remember that there are often as many cases *after* a peak as before it.

dearpandemic.org/are-cases-peak…
3/ How can we enjoy moments w/ family & friends & lower the risk of illness?

💥 Small steps you take to reduce risk are worthwhile. A little bit better…is a little bit better.

Prevention steps that work for COVID will reduce the risk of RSV, flu, & many other nasty viruses.
Read 14 tweets
May 4, 2022
1/ Q: Has almost everyone been infected with COVID by now?
A: Recent estimates suggest around 58% of the population in the US and over 70% in England have been previously infected, with BIG increases during the Omicron wave.

dearpandemic.org/numbers-infect…
2/ A recent @CDCgov MMWR report estimated seroprevalence from a convenience sample of blood collected for medical tests.

➡️Roughly 58% of Americans showed evidence of previous SARS-CoV-2 infection in their blood by Feb '22.

cdc.gov/mmwr/volumes/7…? Image
3/ ➡️ During the Omicron wave from December 2021-February 2022, this estimate increased from 33% to 58%.
➡️ Rates vary a lot by age, ranging from 33.2% for those over age 65 to 75% for those under age 18.

cdc.gov/mmwr/volumes/7… Image
Read 15 tweets
Apr 29, 2022
1/Q: Did getting exposed to fewer germs for the last 2 years weaken our immune systems?

We've been hearing this question a lot.
dearpandemic.org/fewer-germ-exp…
2/ Not likely. If your kids are suddenly getting sick a lot, this is likely due to “catching up” on exposures rather than a weakened immune system.
3/ Many families w/ young kids have been hunkered down for the better part of 2 years– a good % of a young child’s entire life. While isolation had *many* downsides, we can agree that not having to suction snot out of infant noses or clean up norovirus puke was a happy upside.
Read 18 tweets
Jan 27, 2022
1/ Q: Are cases peaking? That means it’s all downhill from here, right?

A: Sort of…. Remember that even if cases come down as quickly as they rise, there will be as many cases *after* the peak as before (think area under the curve).

dearpandemic.org/are-cases-peak…
2/ ➡️ And if the downward slope is *slower* than the rise, we will see *more* cases during the decline from a surge.
3/ Burning fast could be a silver lining of super transmissible #Omicron. Cases rose & fell quickly in S. Africa (w/ hospitalizations & deaths still lagging). The UK appears to have turned the Omicron corner. Many US states appear past their peak in cases, w/ regional variation:
Read 17 tweets
Dec 30, 2021
1/ Q: Case numbers are jumping QUICK! What should I be doing?

A: Share your gifts without sharing COVID. Helpful gestures come in many shapes.

dearpandemic.org/what-should-i-…

#Omicron #ThoseNerdyGirls
2/ One HUGE help: Cancel non-essential plans.

Unfortunately, this includes New Year’s Eve plans. The perfect storm of a new variant & holiday get-togethers is hitting communities & health care w/ FORCE! Testing is in short supply.
3/ Health care is under extreme pressure with surging cases. If you can avoid even one additional contact, you are helping. This is a temporary and urgent request (from a health care provider).

#MedTwitter #HCWs @IMPACT4HC
Read 10 tweets
Dec 21, 2021
1/ Q: Is it true that #Omicron is less severe than previous variants?

A: We HOPE so, but we don’t know yet. The evidence so far is mixed.

dearpandemic.org/is-omicron-les…
2/ We are WAY past due for some good variant news. But pinning our #Omicron hopes on a less virulent variant is not wise for 2 reasons:

1) It might not be less severe in those who are “immune naïve” (neither vaccinated nor with a previous infection—still millions of people).
3/ 2) Many more infections *even* if less severe can still lead to an avalanche of hospitalizations and deaths, and the risk of long Covid.

@AdamJKucharski raised this last December w/ the rise of Alpha:
Read 25 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(