Unique Initiative: As #COVID19 spreads to rural pockets of Delhi, Govt. to create task force called 'Nigrani Samiti' for effective containment of the virus and enforce COVID appropriate behaviour among the residents. (1/4) @ArvindKejriwal google.com/amp/s/indianex…
Delhi Disaster Management Authority stated every task force will be made up of a patwari, a local civil defence warden and two members of the village committee to assess the ground situation and submit its report regularly to the SDM/tehsildar concerned. (2/4)
The teams will create awareness through posters, wall paintings and distribution of pamphlets. They will have to ensure regular spraying of disinfectants like sodium hypochlorite solution in public places like chaupals and akhadas. (3/4)
The commission will involve local cable channels and operators for targeted messaging, preferably involving local celebrities, and using social media platforms and WhatsApp groups to create awareness. (4/4)
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Thrombosis is a major manifestation of COVID-19 that contributes to poor outcomes. Vitamin K plays a crucial role in the activation of both pro & anti-clotting factors in the liver, prevent elastic fiber degradation, possibly prevent comorbidities. THREAD
1. Matrix Gla protein (MGP) is a vitamin K-dependent inhibitor of soft tissue calcification & elastic fiber degradation. Severe extrahepatic vitamin K insufficiency is recently demonstrated in COVID-19 pts, w/high inactive MGP levels correlating w/elastic fiber degradation rates.
MGP Protects against elastic fiber degradation that provides deformability to the lungs & arteries, which facilitates respiration & circulation. The balance between elastic fiber degradation & repair is of vital importance in cardiac & pulmonary health. nature.com/articles/38607…
Thread: Antioxidant & Anti-inflammatory phytonutrients could target the pathogenesis of #COVID19.
Do phytonutrients have the capacity to enhance immunity? Existing literature and evidence to support the hypotheses for 4 phytonutrients & 2 micronutrients. frontiersin.org/articles/10.33…
1. Curcumin:
a. Inhibits the production of pro-inflammatory cytokines (IL-6 and TNF- α) in lipopolysaccharide (LPS)-stimulated BV2 microglial cells and IL- 1β and IL-6 in TNF-α treated HaCaT cells via inhibiting the NF-κB and MAPK signaling pathways. pubmed.ncbi.nlm.nih.gov/17883952/
b. Curcumin exerts an antiviral effect on a broad range of viruses including influenza virus, adenovirus, hepatitis, human papillomavirus (HPV), human immunodeficiency virus (HIV), herpes simplex virus−2 (HSV-2), and Zika viruses. ncbi.nlm.nih.gov/pmc/articles/P…
A study by the International Food Policy Research Institute analyzed health data from more than 250,000 individuals of all ages residing in rural and urban areas in India and observed that crop burning worsened respiratory health in Haryana. (2/4) academic.oup.com/ije/article/48…
Pollutant levels are found to be elevated by 2-2.5 times of the standard value during the crop residue burning period in Haryana and Punjab, reveals a study conducted by the PGIMER. (3/4) tribuneindia.com/news/archive/p…
A diet that recommends eating only one food or a group of foods for all meals throughout the day to lose weight. The most harmful side effect of this diet in long term is nutritional deficiencies. (1/7) healthline.com/nutrition/mono…
How people follow the diet?
On the mono diet, you should stick to just one food item or food group for each meal. Most people follow the mono diet for a few weeks before transitioning back to a healthy, balanced diet. This is mostly a quick fix to lose weight. (2/7)
What foods can be eaten?
Nearly any food can be consumed on the mono diet, including potatoes, apples, eggs, and bananas. Some variations involve sticking to one specific food group, such as meats, fruits, vegetables, or legumes. (3/7)
How does #VitaminD prevent complications in severely affected #COVID19 patients (approx. 20% of hospitalized patients develop serious symptoms) by managing the cytokine/bradykinin storm, ARDS, and organ damage? Thread
1. Cytokine Storm:
a. Vitamin D decreases the production of Th1 cells. Thus, it can suppress the progression of inflammation through reducing the generation of inflammatory cytokines such as IL-6, IL-8, IL-12, and IL-17. pubmed.ncbi.nlm.nih.gov/16142846/ pubmed.ncbi.nlm.nih.gov/21047796/
b. Vitamin D also decreases the generation of TNFα and nuclear factor-κB (NFκB). Moreover, 1,25(OH)2D, a biologically active form of vitamin D, directly inhibits gamma interferon (IFN-γ) and IL-2. pubmed.ncbi.nlm.nih.gov/18717824/ pubmed.ncbi.nlm.nih.gov/6427926/
Delhi LNJP Hospital set an example by treating 8,000 #COVID19 patients, the highest by any state-run facility in the country so far. Congratulations to the doctors, paramedics, State Health Ministry, & CM Shri @ArvindKejriwal. Thread on LNJP's contribution during COVID 19. (1/5)
Plasma bank & plasma therapy: Delhi’s second plasma bank for COVID-19 patients treated 114 patients with oxygen saturation level below 93% and it improved the oxygen levels from 85 to 95%. (2/5) ndtv.com/india-news/pla…
To ensure fulfillment of the need of wards, departments & patients, LNJP installed a new state-of-the-art Live Patient Monitoring System to support all the frontline healthcare warriors working at the dedicated COVID facility. (3/5) newindianexpress.com/cities/delhi/2…