Dr. David Williams speaking at #AHA20
💸Pay gap for Black Americans is 59 cents vs $1 for White Americans
🛑Same as 1978!
Racial differences haven't changed in all this time
At every level of education, gap persists: income and education matter but race overrides this
Racial Segregation is real #AHA20 and was part of racial regulation
💔2/3 of all Black Americans live in very low opportunity neighborhoods
💔This access to opportunity (or lack thereof) is a driver of racial ethnic differences
The consequences of lack of opportunities increases all level of stressors and the consequences are real:
▶️Accelerated aging
▶️Premature aging
▶️Earlier onset of chronic diseases #AHA20@AHAMeetings#racism#racisminmedicine
MLK Jr Said it best:
“It may well be that we will have to repent in this generation. Not merely for the vitriolic words and the violent actions of the bad people, but for the appalling silence and indifference of the good people who sit around and say, "Wait on time.” #AHA20
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#AHA20#preeclampsia
🤰Preeclampsia is an exaggerated response of pregnancy induced inflammation, hyperlipidemia and hypercoagulation
⬆️ risk of:
🧠seizures
🧠stroke
🧠cognitive decline
🤰⬇️seizure threshold
🧠#preeclampsia ⬆️ this susceptibility
Dr. Peter Rothwell: Paul Dudley White lecture & reminds us that PDW was ahead of his time, believing lifestyle was key. The Pathway along the Charles River is named after him #AHA20
Best quote " I wish we could do something useful with tobacco- like making fertilizer out of it"
Profound effect BP on Risk of Stroke #AHA20
🧠🫀 #BloodPressure... #PDWLecture
16 Fold risk association with mean BP and stroke
#mSToPs Study presented at #AHA20#LBCT@SteveSteinhubl@EricTopol
💫Lifetime risk of Afib ⬆️ (.40%)
💥Risk of #Afib is stroke but also Heart Failure and CV Mortality is even ⬆️⬆️
🥅 was to assess ECG patch in diagnosis of Afib & improve outcomes
Study Design of #mSToPs was direct to participants @Aetna patients with #ziopatch worn for a median time of 24.7 days #AHA20
🔺3 year clinical outcomes
🔺Control arm (standard of care)
🔺Pre-specified Primary Outcome time to 1st event
💥Time to diagnosis af #Afib greater in intervention arm
w/ 32% by patch/68% clinically
🔺OAC in ~40%
💃40% female #aha20#LBCT
@AnastasiaSMihai@loriannpeterso1 & I will be presenting Poster #1432 at #AHA20. It will be presented at 9am CT (soon) but before it is, I want to thank you all for filling out my survey on #cardioTwitter because this is what our poster is based on.
We wanted to find our how you measure #bloodpressure & how reliable you felt your clinical BPs were. I regret to inform you despite you liking your BP reads & trusting them, most of you don't check it correctly @HeartBobH#AHA20 Thanks to @Heart_SCCT@ASPCardio@HBPRCA for help
When you measure #BP this is how we need to do in clinic @HeartNews but most people don't #AHA20
#ESCCongress#LoDoCo2 Results #LBCT
Colchicine also a winner of @escardio 2020
This study was building on COLCOT results in secondary prevention in patients w/ chronic CAD
🔺5522 patients enrolled
🔺Randomized to Colchicine 0.5 mg vs Placebo
🔺Excluded advanced CKD, HF, valve ds
Characteristics of #LoDoCo2#ESCCongress
🔺90% of patients tolerated medication
🔺Mostly men (84%)
🔺Most had prior revascularization
🔺 Most well treated
Results of #LoDoCo2 show dramatic effect of colchicine in these patients with chronic CAD
♥️30% reduction in treatment arm for Primary Outcome
♥️28% ⤵️ in MACE
♥️subgroup analysis shown #ESCCongress#residualrisk#colchicine#inflammation
#ESCCongress@MaasAngela presenting on IHD in perimenopause:
So Who is at risk? And why?
♥️Hormones fluctuate over a lifetime in BOTH men &💃♥️There are benefits of estrogen in women protecting them but at menopause it changes and more risk factors ⤴️the risk for ♥️ disease
@MaasAngela#ESCCongress
🔺⤴️insulin resistance
🔺⤴️inflammation
🔺⤴️ adverse cardiometabolic risk profile
All seen in menopause, increasing the risk of CVD in 💃
#ESCCongress@MaasAngela
✅we know a lot about obstructive CAD
❎WE do not know enough about Coronary Vasomotor disorders or Microvascular disorders (INOCA/MINOCA)- these affect 💃
Our knowledge about assessment & treatment of non obstructive CAD remains limited @Drroxmehran