Thread by @DrMarthaGulati

#mSToPs Study presented at #AHA20 #LBCT @SteveSteinhubl @EricTopol
💫Lifetime risk of Afib ⬆️ (.40%)
💥Risk of #Afib is stroke but also Heart Failure and CV Mortality is even ⬆️⬆️
🥅 was to assess ECG patch in diagnosis of Afib & improve outcomes

Study Design of #mSToPs was direct to participants @Aetna patients with #ziopatch worn for a median time of 24.7 days #AHA20

🔺3 year clinical outcomes
🔺Control arm (standard of care)
🔺Pre-specified Primary Outcome time to 1st event
💥Time to diagnosis af #Afib greater in intervention arm
w/ 32% by patch/68% clinically
🔺OAC in ~40%
💃40% female
#aha20 #LBCT

So here are the findings of #mSToPs #AHA20 #LBCT @AHAMeetings:
💥⬇️death, MI, Stroke, emboli in monitored arm
💥 Greatest ⬇️ in those with #afib diagnosed by patch

#mSToPs #AHA20 #LBCT
💥Impressive findings mostly due to reduction in mortality
💥Less bleeding in active monitor arm (?)
💥Certainly some confounding based on who chose to wear this, claims data etc
💥pragmatic study: needs replication but shows how trials can be done