Thread by @MJGriksaitis

Allan Doctor discusses the functional assessment of haemostasis and anticoagulation therapy during critical illness

#PedsICU #WFPICCS20

let’s look at normal #coagulation system #physiology...

New ways of thinking at a cellular level moves from the classic intrinsic and extrinsic a pathway to a cell based process consisting of:
- Initiation
- amplification phase
- propagation phase

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And fibrinolysis is an important part of #coagulation #physiology to prevent excess clot growth and clot break down after healing...

It is this process we accelerate with thrombolysis

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So how do we monitor anticoagulation?

Each has pro and cons, and often you need multimodal monitoring

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This is a great slide: how to integrate #TEG interpretation with your patient who is bleeding or clotting (From Dr Allan Doctor)

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