Is anyone planning to do some reading about hippocampal neuroanatomy over the holidays?
If you answered, "yes", this week's #SubfieldWednesday is for you! We will give you a list of "must read" atlas references about our favorite brain structure. 🍤❣️
Duvernoy's Chapter 7: "Sectional Anatomy and Magnetic Resonance Imaging" is especially helpful for helping the reader visualize the subfields on MRI and post-mortem sections.
Insausti & Amaral's, "The Hippocampal Formation" is another commonly cited atlas. The definitions in Figure 23.15 influenced a number of existing MRI protocols.
Insausti, R., & Amaral, D. G. (2004). The Human Nervous system. Hum. Nerv. Syst, 871-914.
The Atlas of the Human Brain by Mai and colleagues is another useful atlas. It contains both cell (Nissl) and fiber (Weigert) stains of the whole brain.
Ding, & Van Hoesen. (2015). Organization and detailed parcellation of human hippocampal head and body regions based on a combined analysis of cyto‐and chemoarchitecture. Journal of Comp Neurol, 523(15), 2233-2253.
Hello and happy #SubfieldWednesday! Today we are going to get a bit more familiar with how the hippocampal subfields differ in their composition of different cell types, cell sizes, and layer thickness. 🍤🔬
Here are some images taken from five different hippocampal subfields (CA1, CA2, CA3, dentate gyrus, and subiculum). Can you tell which number corresponds to which subfield? 🤔
Because a Nissl stain was applied to these slices, the cell bodies appear dark purple. This allows neuroanatomists to characterize the size, shape, and relative spacing of the cells.
This quiz even stumped some of us at @hipposubfields headquarters! We had to contact a neuroanatomist to confirm which answer is correct! (or at least "the most correct")
Braak and Braak (1985) originally described the transentorhinal cortex as a 'transition region between entorhinal cortex and temporal isocortex. This rules out answer A (part of ERC)
Hello subfield-fans! Last week's #SubfieldWednesday topic was the layered composition of the hippocampal subfields. We learned that the subfields contain three major cellular layers which makes them a part of the allocortex.
Even though the hippocampus sometimes gets grouped together with subcortical structures like the thalamus and basal ganglia, the dentate gyrus, CA fields, and subiculum are all part of a special type of cortex called the allocortex!