This may be the right direction, in fact our recombinant protein vaccine might be a great booster. Problem is this: Zero experimental evidence. While it’s something I’ve suggested in lab meetings, zoom calls, without actual data in hand it’s a non-starter nytimes.com/2021/01/01/hea…
Op Warp Speed delivered vaccines, but they went heavy in the direction of new technologies oblivious to a reality that we don’t have a health system in place to deliver them high throughput. We’re opening 40 million IKEA boxes, just now reading the “assembly required”stickers
It’s why we pushed for our low cost, easy to deliver recombinant protein vaccines now being scaled for production and tested across India 🇮🇳 , a 40 year old well tested technology, safe for use in kids.
In the meantime, by not launching a national COVID19 control strategy, our backs are against the wall. We have no choice but to vaccinate ourselves out of this mess. The numbers are daunting: I estimate 240 million people must be immunized by September, one million people per day
Relying on pharmacy chains and supermarkets won’t deliver on the scale required. And certainly not in pharmacy deserts 🌵 in low-income areas. We need to call an audible that focuses on large stadiums well staffed with medical personnel and approve vaccines that go beyond mRNA
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Texas hospitals have received over 600,000 doses yet only about 100,000 vaccinated so far? These aren’t bottles of Cabernet Sauvignon. We don’t need age vaccines, are we overthinking this? Texas 1b lots of adults with underlying conditions, vaccinate them houstonchronicle.com/news/article/T…
There’s no reason to hang on to vaccine stocks (except for second doses), just move them out and get people vaccinated ASAP. More vaccine is coming
Maybe I’m too subtle. So here it goes: 1. In 2020 we royally messed up COVID19 control, failing to launch a US strategy causing 350,000 deaths 2. By failing, we backed ourselves into a corner 3. Our last hope is to now vaccinate our way out of this. 4. Ignore antivax conspiracies
THREAD 1/5: I know this is not very nice just a couple of days before Christmas but I have to say I'm concerned about the CDC press release today, and the status our virus genomics surveillance program SPHERE
THREAD 2/5: Here's the statement: "Given the small fraction of US infections that have been sequenced, the variant could already be in the United States without having been detected"
THREAD 3/5: And this one: "The VOC 202012/01 variant has not been identified through sequencing efforts in the United States, although viruses have only been sequenced from about 51,000 of the 17 million US cases"
1/5: Many thanks @EricaRHill @JohnBerman for hosting me on @NewDay: I voiced strong opinions this AM on how to proceed regarding the emergence of the the SARS CoV2 variant B.1.1.7. Bottom line: Not a question of opinion, it’s an evidence based decision
2/5: Over the Summer the CDC launched SPHERES, a virus genomics sequencing consortium, a similar approach led the UK to discover variant 1.1.1.7. We should therefore already know if the new variant has entered the country. cdc.gov/coronavirus/20…
3/5: My expectation is that by COB today, the CDC will inform the American people: 1) If indeed the virus has entered the US, 2) its extent, where and if it's outcompeting other virus strains, 3) epidemiologic models showing how quickly it is expected to spread, and...
2/4: Also with mixed emotions X3. 1. Sadness & Grief: Reflecting on the 300,000 Americans who lost their lives from #COVID19. Those who never had this opportunity, because our nation could never organize a national plan roadmap. How I tried to push WH to implement an Oct 1 Plan
3/4: Gratitude: Thankful to @pfizer@BioNTech_Group and to the leadership of OpWarpSpeed, including our @HHSGov agencies: @US_FDA@CDCgov and to the @NIH supporting more than a decade of R&D on coronavirus vaccines including ours now being produced and tested in India 🇮🇳
Many thanks @AymanM hosting me @MSNBC on this first full day of #covid19 vaccination in America. I explained why the Pfizer-BioNTech vaccine is both effect and safe and = the culmination of 17 years of R&D from a community of CoV virologists including our group
The vaccine then went through a rigorous phase 1 and 2 trials, showing that we need to 2 doses to get the virus 🦠 neutralizing antibodies up, and then a large 44,000 person phase 3 trial equivalent in size to any typical vaccine trial in the US
After that it will go through rigorous post EUA monitoring through VAERS VSD and additional FDA and CDC monitoring.
1/3: Always an honor to be on @CNNTonight with @donlemon the night before possible first release of #covid19 vaccines to the American people. Recent polls show high rates of vaccine hesitancy and refusal, here are the + and - forces...
2/3: On the + side I think as people see their family, friends, colleagues get vaccinated, things will pick up. Also the high level of reported protective immunity will be a driver...
3/3: On the - side there is no real communication strategy from OWS even though it is a strong program scientifically. The void is filled with pharma CEOs who are mostly poor and tone deaf communicators + powerful antivaccine groups dominating internet + Russian disinformation