1/ @MGHAllergy @BWHAllergy @vumc_cdsi_rsch #vaccine and #drugallergy experts provide a clear and concise approach to safely evaluate those with a history of #anaphylaxis and anyone with an #allergicreaction reaction to the first dose of @Pfizer or @Moderna #CovidVaccine.
2/ See our updated manuscript @JACIInPractice that includes information on #skintesting using non-irritating skin test concentrations to #PEG and #polysorbate and when to consider #skintesting jaci-inpractice.org/action/showPdf…
3/ The potential life-saving benefit of vaccination makes it essential that we carefully evaluate every possible #allergicreaction to prevent denying access to the vaccine unnecessarily. Our knowledge is rapidly evolving and future recommendations may change with more data.
4/ Special thank you to my co-authors who supported this effort and helped get this across the finish line (a second time) despite quite a few hurdles. What a marathon! @KimberlyBlumen1 @AnnaWolfsonMD @rebeccasaff @PaigeWickner @LaceyRobinsonMD @AidanLongMD

• • •

Missing some Tweet in this thread? You can try to force a refresh

Keep Current with Aleena Banerji, MD

Aleena Banerji, MD Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!


Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @AleenaBanerjiMD

10 Jan
1/ New guidelines from the @US_HAEA Advisory Board are now available @JACIInPractice. We provide an update on classification, diagnosis, on-demand/prophylactic tx with special considerations for women/children along with guidance on development of a comprehensive management plan.
2/#HAE can be broadly divided into #HAE due to C1INH deficiency (type 1 and type 2) and HAE with normal labs (4 mutations now identified - factor XII, plasminogen,
angiopoetin-1, and kininogen). Early diagnosis is critical. If you suspect send C4, C1INH level and function.
3/All patients with #HAE must have ready access to effective on-demand medication and trained in self-administration. Encourage on-demand treatment of all #HAE attacks. Four FDA approved on-demand treatments available (ecallantide, icatibant, pdC1INH, or rhC1INH)
Read 5 tweets
1 Jan
1/ As #Allergists, built upon the recommendations of U.S. regulatory agencies, we can provide clear steps to the medical community on how to safely administer both doses of the #COVID vaccine in individuals with #allergic histories. #AIMedEd jaci-inpractice.org/article/S2213-…
2/ Neither the #PfizerBioNTech nor #Moderna #COVID19 mRNA vaccines are formulated with any food, drugs, or latex, but both contain the excipient #PEG. However, to date, confirmation that PEG is the cause of reactions to #CovidVaccines is lacking.
3/ Complement-activation-related pseudoallergy, vasovagal reactions (well known cause of hypotension), anxiety symptoms or vocal cord dysfunction can mimic symptoms of severe allergic reactions. Serum #tryptase, complement studies, and #PEG antibodies may be helpful.
Read 6 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!