Tro Profile picture
31 Jan, 10 tweets, 2 min read
THREAD ALERT 🚨🚨

Let's play the game where I call out all the dogma in an editorial against meat consumption from a plant-based proponent

I wish I was joking, but "environment/TMAO" both mentioned in the paper 🤔

doi.org/10.1093/ajcn/n…
DOGMA #1

"The absence of RCTs on this topic is explained by insurmountable challenges"

We have plenty of trials with ketogenic diets, rich in red meat that improve glycemia and metabolic syndrome.
DOGMA #2

"The time frame is daunting due to the nature of chronic diseases that develop over decades before they present as incident cases."

Thankfully we can use CGMs & not dogma to demonstrate that glycaemia in DM2 is immediately ameliorated by adding meat & removing carbs
DOGMA #3

"The sample size needed ... is in the thousands."

Wrong. You can prove the opposite quite easily and elegantly. Take 10 poorly controlled diabetics and feed them meat versus your vegan progananda, wait 12 hours, follow for as long as you need, days, weeks, months....
DOGMA #4

"Accurate monitoring of adherence is beyond the capacity of currently available assessment tools"

Wrong, remotely monitored weight, CGMs, breath ketones and serum ketones could easily monitor adherence. Some of us already do this.
DOGMA #5

"RCTs of red meat consumption and incident chronic disease clinical outcomes have never been conducted, and likely never will."

So, stop publishing shit trials, confounded by healthy user bias, to peddle dogma and start publishing trials that will matter
DOGMA #6

"Mechanistic plausibility of beneficial effects on glucose and insulin dynamics, or inflammation, from substitution of specific comparators for red meat..."

bullshit. Eat meat, use a CGM, check crp, not hard to disprove, its been done u are just ignoring the data
DOGMA #7
"It is beyond the scope of this editorial to build an evidence-based mechanistic case for each comparator based on the unique differences each one has in the set of nutrients and dietary components listed above."

Because its all lies and dogma.
DOGMA #8
"Another relevant line of evidence—planetary health"

PEOPLE's NUTRITION BEFORE YOUR DOGMA

Children IQ benefits from meat, MetS/diabetic patients benefit from meat (see Virta), plant-based dogma associated with poor mental health, osteoporosis/sacropenia.
DOGMA #9

"CG received gift funds from Beyond Meat in 2019 that were used to conduct an RCT comparing red meat to Beyond Meat products."

Lets be clear, I am biased. I heal people with meat. Lets also be clear. You are biased.

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More from @DoctorTro

12 Nov 20
THREAD 🚨

tears roll down my face right now

I just saw a patient who had a gastric bypass 10 years ago, who regained all her weight & the surgeon “upgraded” her to a duodenal switch

1/
She has been re-hospitalized several times after the procedure several months prior with multiple complications

2/
I asked her if anyone had ever talked to her about diet and she said yes the nutritionist told her to count calories and review the myplate

I asked her, given her history of diabetes had anybody mentioned low carb dieting, she said no.

3/
Read 11 tweets
29 Sep 20
Let’s talk about LDL and low carb diets.

🚨 THREAD FOR DOCTORS 🚨

Let’s first address the issues, you have no clue what you are looking at on a lipid panel.

Now since that’s out of the way, let’s let the education begin.
The conventional medical knowledge is that LDL is causative for CVD.

Many models have shown this, namely drug trials, Mendelian randomization, gene defect analyses and population association data
This is aggregated data from primary and secondary prevention trials

It appears that in both primary prevention there is a nominal improvement in CVD with LDL lowering whereas in secondary the benefit seems more robust

Nnt 200-500 in 1*
NNT 100-200 in 2* Image
Read 18 tweets
29 Sep 20
THREAD 🚨

Let’s talk about the headlines about time restriction!

Firstly I want to commend @ethanjweiss and all for a well designed study.

I poured through the data and wanted to share my thoughts.

jamanetwork.com/journals/jamai…
Basically the TRE group had more weight loss and fat loss although it wasn’t statistically significant.

Interesting on DXA it appears that there was a statistically significant reduction in lean mass.

Where did this come from?
Do we think that eating 12-16 hours of the standard diet would lead to significantly more lean mass than 8 hours?

It doesn’t seem likely.

So where did it come from?

The answers may be in the supplemental.
Read 7 tweets
29 Sep 20
Review of the supplemental from @ethanjweiss lead to some interesting findings.

EXERCISE:
The late TRF group had decreased activity, daily movement, METS, steps, high activity, training frequency and training volume

The TRF group exercised less! Much less!

1/4
SLEEP:
They also had worsened sleep timing/efficiency & more awake time

This could be an issue with meal timing close to sleep. eTRF versus lateTRF

2/4
HEAD SCRATCHERS...literally

Interestingly, the HEAD AREA of the TRE group also shrunk (statistical significance) 🤔

Also TRE preferentially decreases right arm lean mass 🤔

I talked with Dr. Weiss to access the data to correlate LBM with BIA, stay tuned

3/4
Read 6 tweets
27 Sep 20
Total Sugar Intake and Macro and Micronutrients in Children Aged 6-8 Years: The ANIVA Study. Morales-Suarez-Varela M, Peraita-Costa I, Llopis-Morales A, Picó Y, Bes-Rastrollo M, Llopis-Gonzalez A. Nutrients. 2020;12(2):349. Published 2020 Jan 29. doi:10.3390/nu12020349

💥💥💥💥
Synergistic effects of fructose and glucose on lipoprotein risk factors for cardiovascular disease in young adults. Hieronimus B, Medici V, Bremer AA, et al. Metabolism. 2020;154356. doi:10.1016/j.metabol.2020.154356
Added sugar intake and cardiovascular diseases mortality among US adults. Yang Q, Zhang Z, Gregg EW, Flanders WD, Merritt R, Hu FB. JAMA Intern Med. 2014;174(4):516-524. doi:10.1001/jamainternmed.2013.13563

💥💥💥💥
Read 8 tweets
26 Sep 20
🚨 THREAD ON COVID (it’s going to get ugly) 🚨

•no politics 🙏
•no crazies 🙏

Today I watched segments of an interview with a prominent immunologist (name rhymes with ouchy)

This scientist said he doesn’t believe in T-cell immunity for the novel coronavirus

1/11
Now, I’m certainly no expert in immunology but I decided to educate myself

I started here and here

bmj.com/content/370/bm…

nature.com/articles/s4158…

I also read these key citations below on T cell immunity

2/11 Image
How can a prominent immunologist not consider this early body of research? So I thought about potential roadblocks to accepting new data... a process called anchoring bias

This is a bias that’s created when you commit to an outcome & don’t assimilate new info as it arises

3/11
Read 12 tweets

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