Indiana University Infectious Diseases Fellowship
11 Feb,
6 tweets, 3 min read
#idboardreview 30 F return from (2wk visit to) Togo 🇹🇬 3d ago now/fever, chills, rigors. Thin smear shown. Diagnosis? #medEd #idmedEd #IDtwitter 
#plasmodium #ovale moderately enlarged fimbriated red cells with shuffner stippling, amioboid trophozites
P. #ovale #malaria is endemic to tropical Western Africa. It is relatively unusual outside of Africa and comprises less than 1% of isolates where found. It is also seen in the Philippines, Indonesia, and Papua New Guinea, but is relatively rare in these areas
The life cycle of P. #ovale includes hypnozoites, which are dormant stages in the liver. These stages can be reactivated in weeks, months, or years after the initial infection, causing disease relapse.
#ovale Chloroquine and or an artemisinin combination therapy. After fever has subsided: Primaquine is required to eradicate the hypnozoite liver stages
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