NEW—CDC warns #COVID19 is "on the cusp" of potential resurgence, with cases & deaths rising. Highly-transmissible #B117 variant can "hijack our successes", as fatigue leads precautions being "flagrantly ignored".
Been warning for over a month. So tired.
2) The #B117 is serious. It is not only 40-60% more contagious, but also more severe. And it also might be causing kids outbreaks worldwide. Italy 🇮🇹 is just one. Israel too.
4) #B117 is currently 20-25% of all #COVID19 cases now in the US. It’s looking bad. Likely 50% by end of the month - maybe March 20-25th. Mark my words. It will cause a serious surge in April. helix.com/pages/helix-co…
5) This was #B117 last month once schools reopened in UK... notice how much it diverged. They were dropping in lockdown... but clearly kids stood out differently.
8) We were warned a resurgence is coming once #B117 takes over. Denmark’s CDC predicted it. They tried to warn very harshly. Now we reap the neglect that we sow...
10) We all want kids back in school, but SAFE SCHOOL is the key. Luckily the CDC just released guidelines last Friday on safe school and ventilation...
📍STARK WARNING—“Whatever #SARSCoV2 variants summit that peak could be a considerably bigger problem than any variants that we know”—with “any combinations of increased transmissibility, altered virulence and/or ⬆️ capacity to escape population immunity.” medrxiv.org/content/10.110…
2) “The emergence & rapid rise in prevalence of three independent #SARSCoV2 '501Y lineages' #B117#B1351#P1 has prompted renewed concerns about the evolutionarily capacity to adapt to both rising population immunity and public health interventions such as vaccines & distancing.”
3) “Viruses giving rise to 501Y lineages have, presumably under intense natural selection following a shift in host environment, independently acquired multiple unique & convergent mutations. As a consequence all have gained properties that likely complicate control of #COVID19.”
💡EFFECTIVE—Single-dose Oxford–AstraZeneca #COVID19 vaccine followed by a 12-week booster. Vaccine efficacy was significantly higher at 81·3% after two standard doses given at an interval of >=12 weeks, versus 55·1% when doses <6 weeks apart. Good news! 🧵 thelancet.com/journals/lance…
2) “findings were supported by immunogenicity studies done in participants who were younger than 55 years, showing anti-SARS-CoV-2 spike IgG antibody responses more than two-fold higher in those who had a dose interval of >=12 weeks than in those who had an interval of <6 weeks”
3) “Notably, efficacy against any nucleic acid amplification test-positive cases, including symptomatic and asymptomatic or unknown cases, was 63·9% (46·0 to 75·9) after a single standard dose, suggesting the possibility of reducing viral transmission.”
JAPAN 🇯🇵 WARNS OF POTENTIAL “FOURTH WAVE”—Over 230 cases of highly infectious variant strains of the novel coronavirus have been confirmed in in Japan. Experts warning of a potential "fourth wave" should they continue to spread across the country. #COVID19 english.kyodonews.net/news/2021/03/0…
2) Here is one of the new Japan outbreaks of #B117 —linked to a school for kids under 10. This matches a lot of other trends on elevated B117 risk in kids.
This is the most worrisome article on anti-vaxxer movement in a long time. It’s so insane... it makes my blood boil how prevalent science denialism is in evangelical community. And it’s hurting pandemic mitigation. #COVID19 google.com/amp/s/www.wash…
2) “on TikTok, young Christians act out biblically inspired scenes in which they are forced to take a vaccine, only to end up splattered in fake blood and on the brink of death—to represent how the introduction of coronavirus vaccines could herald the biblical End Time.”
3) “Along with hundreds of thousands of other vaccine-questioning posts by social media users all over the world, they’re demonstrating the ways in which health misinformation is targeting Christians, some reaching sizable audiences.
📍SCHOOL OUTBREAK OF #B117 in JAPAN 🇯🇵—Eleven people north of Tokyo have been infected with a new B117 #COVID19–none have any UK travel history. 6 cases were kids under 10. Ten of the infected all linked to a school for kids age <10. Matches kids trend. 🧵 mainichi.jp/english/articl…
2) This matches the latest UK 🇬🇧 data showing kids age 5-12 have the highest positivity of #COVID19. And in England, the #B117 is nearly 95-99% dominant variant.
3) Meanwhile, here is latest French data. Kids 0-9 have now the highest % of #B117 of any age group. And very sharp trend towards more B117 the younger one is.
UNIVERSITY OUTBREAKS—In all 3 UK universities studied, #COVID19 cases increased amongst students shortly after term began—number of outbreaks identified. Following increased tests, use of remote learning & self-isolation by students—cases quickly dropped. cogconsortium.uk/investigating-…
2) In general, the outbreaks were observed to start from multiple introductions of the virus, with infections thought to originate from both students’ home residence communities and also the local communities in which the universities are found.
3) “Most outbreaks appeared to grow by student to student transmission of a subset of the initial infections. In Cambridge and Portsmouth, systematic testing allowed **asymptomatic spread** between students to be tracked and was **found to play a role in outbreak growth**. ⚠️