UNIVERSITY OUTBREAKS—In all 3 UK universities studied, #COVID19 cases increased amongst students shortly after term began—number of outbreaks identified. Following increased tests, use of remote learning & self-isolation by students—cases quickly dropped. cogconsortium.uk/investigating-…
2) In general, the outbreaks were observed to start from multiple introductions of the virus, with infections thought to originate from both students’ home residence communities and also the local communities in which the universities are found.
3) “Most outbreaks appeared to grow by student to student transmission of a subset of the initial infections. In Cambridge and Portsmouth, systematic testing allowed **asymptomatic spread** between students to be tracked and was **found to play a role in outbreak growth**. ⚠️
4) “There was some evidence consistent with onward transmission to local communities. Portsmouth in particular, found that infection rates amongst students were considerably lower than age-matched cases in the surrounding community.”
5) “At Cambridge, the largest cluster was examined in detail to understand how the spread had occurred. This cluster was found to include multiple colleges (which act both as accommodation and social hubs), multiple year groups and multiple courses.
6) “Stratification by year of study showed that first year students were by far the most likely to contract and spread the virus, with students in higher years and postgraduates remaining less affected.
7) “The investigation at Glasgow, led by the Health Protection Team at NHS Greater Glasgow and Clyde and Public Health Scotland in a collaboration with MRC-University of Glasgow Centre for Virus Research where sequencing was performed, presents an informative comparison.
8) “This outbreak was contained to off-campus accommodation, primarily student residential halls, highlighting the importance of considering the household, social, and academic context of the student population when assessing transmission risks and implementing control measures.”
9) While kids 5-12 have highest positivity, just behind that age group was college age group of 18-24. Naturally.
VARIANTS IN TEXAS—An awful lot of dangerous variants in the Houston metro area. We have the more contagious & severe 🇬🇧#B117, more reinfection prone 🇿🇦#B1351, super contagious 🇧🇷#P1 & worrisome #P2, plus 2 types of CA #B1429 & #1427. #COVID19
⚠️VERY WORRIED FOR FLORIDA/US—More contagious #B117 is rising quickly, & exponentially replacing the old dying #SARSCoV2 common strain. B117 affects kids, & 64% more severe. B117 now over 40%—dominant in days. A new surge is coming. Florida inaction= Florida ➡️ US surge. #COVID19
2) Been watching this B117 situation for 2 months. We already saw very worrisome signs in Miami Dade this week.
HORRIFYING #COVID19 death curve in one of wealthiest cities in Brazil— Porto Alegre is capital of Rio Grande do Sul— with many top-notch hospitals with better rating than most US🏥. And their health system still collapsed under #P1.
📍STARK WARNING—“Whatever #SARSCoV2 variants summit that peak could be a considerably bigger problem than any variants that we know”—with “any combinations of increased transmissibility, altered virulence and/or ⬆️ capacity to escape population immunity.” medrxiv.org/content/10.110…
2) “The emergence & rapid rise in prevalence of three independent #SARSCoV2 '501Y lineages' #B117#B1351#P1 has prompted renewed concerns about the evolutionarily capacity to adapt to both rising population immunity and public health interventions such as vaccines & distancing.”
3) “Viruses giving rise to 501Y lineages have, presumably under intense natural selection following a shift in host environment, independently acquired multiple unique & convergent mutations. As a consequence all have gained properties that likely complicate control of #COVID19.”