📍SCHOOL OUTBREAK OF #B117 in JAPAN 🇯🇵—Eleven people north of Tokyo have been infected with a new B117 #COVID19–none have any UK travel history. 6 cases were kids under 10. Ten of the infected all linked to a school for kids age <10. Matches kids trend. 🧵 mainichi.jp/english/articl…
2) This matches the latest UK 🇬🇧 data showing kids age 5-12 have the highest positivity of #COVID19. And in England, the #B117 is nearly 95-99% dominant variant.
3) Meanwhile, here is latest French data. Kids 0-9 have now the highest % of #B117 of any age group. And very sharp trend towards more B117 the younger one is.
5) We need to SAFELY REOPEN SCHOOLS. And to do that - we need not just masks - but also VENTILATION AND AIR DISINFECTION. See new CDC guidance released last week. Read thread 🧵
VARIANTS IN TEXAS—An awful lot of dangerous variants in the Houston metro area. We have the more contagious & severe 🇬🇧#B117, more reinfection prone 🇿🇦#B1351, super contagious 🇧🇷#P1 & worrisome #P2, plus 2 types of CA #B1429 & #1427. #COVID19
⚠️VERY WORRIED FOR FLORIDA/US—More contagious #B117 is rising quickly, & exponentially replacing the old dying #SARSCoV2 common strain. B117 affects kids, & 64% more severe. B117 now over 40%—dominant in days. A new surge is coming. Florida inaction= Florida ➡️ US surge. #COVID19
2) Been watching this B117 situation for 2 months. We already saw very worrisome signs in Miami Dade this week.
HORRIFYING #COVID19 death curve in one of wealthiest cities in Brazil— Porto Alegre is capital of Rio Grande do Sul— with many top-notch hospitals with better rating than most US🏥. And their health system still collapsed under #P1.
📍STARK WARNING—“Whatever #SARSCoV2 variants summit that peak could be a considerably bigger problem than any variants that we know”—with “any combinations of increased transmissibility, altered virulence and/or ⬆️ capacity to escape population immunity.” medrxiv.org/content/10.110…
2) “The emergence & rapid rise in prevalence of three independent #SARSCoV2 '501Y lineages' #B117#B1351#P1 has prompted renewed concerns about the evolutionarily capacity to adapt to both rising population immunity and public health interventions such as vaccines & distancing.”
3) “Viruses giving rise to 501Y lineages have, presumably under intense natural selection following a shift in host environment, independently acquired multiple unique & convergent mutations. As a consequence all have gained properties that likely complicate control of #COVID19.”