Investigation by our @serenatinari on @BMJ_latest The @EMA_News Covid-19 vaccine leak show that some early commercial batches of Pfizer-BioNTech’s vaccine had lower than expected levels of intact mRNA, prompting wider questions about how to assess this novel vaccine platform 1/4 
@EMA_news was victim of a cyberattack, the material delivered to journalists and academics. EMA was concerned about manufacturing not producing vaccines to the specifications expected, and unsure of the implications of low mRNA integrity on the vaccine safety and efficacy. 2/4
@BMJ_latest @serenatinari piece on mRNA integrity in Covid-19 vaccines raises questions about the lack of transparency. Companies and regulators said to the journal the specification limit acceptance criteria are commercially confidential @RecheckHealth 3/4
The documents offer the medical community a chance to reflect on the complexities of quality assurance for all mRNA vaccines and especially on RNA instability, one of the most important variables that has thus far received scant attention 4/4
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