📍ITALY 🇮🇹 SCHOOL REOPENING: Nationwide in Italy, 15-20 days after schools reopened, #COVID19 surged. The “rate of growth of daily #SARSCoV2 cases in all Italian regions provides some evidence in favor of a link between school reopening and resurgence”.

Detailed 🧵 by @DGBassani
2) 70% of Italy region saw surges after reopening. The mean time delay was just 16 days!
3) the other regions still had increases. Just longer or shorter time delays.
4) the authors note that “while a 10% increase in in-person work also happened around the same time schools reopened, that affects the contact patterns of 2.5M people, while school reopening affects contact patterns of 11M people (school staff/students).”

➡️Hence mainly schools.
5) Best evidence of school driven outbreaks in the world? Quebec 🇨🇦...

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More from @DrEricDing

12 Apr
US Pentagon has funded a blood filter for a dialysis machine that removes the #SARSCoV2 coronavirus from the blood - FDA has approved it for emergency use. It has been used to treat nearly 300 patients. #COVID19
2) Dr. Matt Hepburn: This is a filter that you can put on a dialysis machine.
"Patient 16", a military spouse, was in the ICU, near death with organ failure and septic shock when she was entered into a Defense Department COVID-19 study (video above)

cbsn.ws/3237WqI
3) Dr. Gaeta: She's liberated from veso-active medications and her septic shock resolved. We also see improvements in her markers of inflammation. Those are all positive prognostic signs.

Bill Whitaker: You pass someone's blood through this--
Read 11 tweets
12 Apr
The most important vaccine in Latin America—SinoVac’s CoronaVac reports new trial results from Brazil 🇧🇷—

Efficacy against symptomatic #COVID19–50.7%. Moderate & severe: 83.7% / 100%. Delayed 2nd dose no issue. Neut. titres lower in age>=60 against #P1.🧵
papers.ssrn.com/sol3/papers.cf… Image
2) Results 12,396 people randomized in Brazil. It seems 2nd dose efficacy wasn’t much diff than 14 days after 1st dose. And delaying 2nd dose didn’t seem to hurt. And a second dose >21 days actually showed no drop in efficacy. ImageImage
3) As for lab antibody neutralization titres, vaccinated people had no real difference for seroconverting (having antibodies) against different variants. That said, among those who seroconverted, neutralization titres was lower among those age 60 and above against #P1 🇧🇷 variant. Image
Read 12 tweets
11 Apr
What’s worse than losing school days during pandemic? Losing a parent.

Nearly ~40,000 children have lost a parent to #COVID19, black children even more.
"The number of children experiencing a parent dying of Covid-19 is staggering.”

cnn.com/2021/04/05/hea…
2) "Black children are disproportionately affected, comprising only 14% of children in the US but 20% of those losing a parent to Covid-19."
3) “The model suggests that each Covid-19 death leaves 0.078 children aged between 0 and 17 parentally bereaved, representing a 17.5% to 20.2% increase in parental bereavement absent of Covid-19”
Read 12 tweets
11 Apr
My god India 🇮🇳... and it’s not just more testing, because positivity had quintupled (5x) in recent month. India could be the next Brazil 🇧🇷 in terms of #COVID19 crisis scale. Image
2) India crisis is also due to mixed messages and complacency, writes @AmyKazmin.

“Mixed messages from the prime minister and health authorities left the public playing down the risk of the virus”
3) I hope people realizes how important India is... it’s also the world’s largest maker of vaccines for COVID. But it recent halted all exports due to this surge. Hence Canada 🇨🇦 is now delayed in its vaccine deliveries due to the crisis there in India. amp.ft.com/content/6f6705… Image
Read 5 tweets
10 Apr
📍You can install more ICU beds & buy more ventilators in a surge. But healthcare workers, you cannot.

📍Equipment is replaceable. Doctors and nurses are not.

📍You can try to pay more to HCW to work more hours, but you can’t if HCWs burn out.

#COVID19 #vaccinate  #ZeroCovid Image
2) Oh but COVID isn’t real some of you say? But next time you get into a car accident and need to goto the ER and get surgery... guess what—ambulance late, ER is over capacity, no operating room or surgeons available to repair that sliced aorta...

Don’t dare say it’s not real.
3) Rose are red... violent are blue...
Read 4 tweets
10 Apr
At least 2700 inmates have died from #COVID19. None deserved it. A month after Bruce Norris had a life sentence commuted, he died of COVID while waiting release. In TX, a new mom w/ only 2-year term, died shortly after giving birth while on a ventilator.🧵
nytimes.com/interactive/20… Image
2) “The virus shot through many institutions, leaving inmates desperate for ways to avoid getting sick. At Pickaway Correctional in Ohio, which housed about 1,900 inmates, they tried to turn bed sheets into tents to separate themselves; four in five inmates were infected anyway.”
3) “At an immigration detention center in Farmville, Va., nearly every detainee — 339 in all — was infected. And at the Fresno County Jail in California, where most inmates are held on charges for which they have not yet been convicted, more than 3,800 were sickened.”
Read 14 tweets

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