Explosion of #B117 across Europe.

We epidemiologists have been shouting from the rooftops since December to no avail. Evidence was clear as day. Now we are in middle of another global surge for the 8th week in a row. #COVID19
2) And it’s not just Europe... India 🇮🇳 and Brazil and countless other places seeing surges driven likely by variants.
3) Anyone remember this damn thread?! How there is a new emerging pandemic surge because variants like #B117 is bifurcating the pandemic into two? Countless didn’t listen.
4) And remember these stark outbreak canary in the coal mine warnings about #B117?
5) So Italy mostly ignored that outbreak in one village. What soon happened? #B117 infecting tons of kids and adults alike. But more kids than last year
6) Not just in Europe, but also #B117 driven outbreaks in British Columbia Canada 🇨🇦 too months ago. Ignored.
7) how quickly we also forget many other #B117 school outbreaks.
8) And they aren’t isolated. These #B117 outbreaks have been around for months in countless places.
9) Show me a nationwide analysis indicating schools. All these anecdotal outbreaks and local data not enough?

Okay... national data analysis of schools in Italy...
10) still don’t believe the mountains of data unless you see how glorious Sweden 🇸🇪 is handling #B117 and cases? Well here you go... Sweden today... also overrun by #B117 and surging.

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More from @DrEricDing

12 Apr
Sweden 🇸🇪 has the highest #COVID19 per capita in Europe for the past week! Its Scandinavian neighbors that didn’t negligently go for natural infection herd... all among the lowest.

Swedish pandemic leadership is an utter failure and likely responsible for pandemicide. 🧵 Image
2) Proof is also in the Swedish excess deaths.... Sweden is the only country in Scandinavia with any.
3) How bad is Swedish excess mortality? 100+ year record bad!
Read 6 tweets
12 Apr
Ummm, HOLY SHIT!

“pretty fucked up that eukaryotic and prokaryotic DNA polymerases arent homologous” ~@halvorz

Trying to now ponder—if humans & archaea share DNA polymerase, but not bacteria, then where the hell did bacteria learn their DNA 🧬 copying system?! Like, WTF.
2) More translation— “completely independently” is an eye popping 😳 phrase.
3) I’m trying to digest this... “super fucked up” is how an evolutionary biologist is describing this.
Read 7 tweets
12 Apr
US Pentagon has funded a blood filter for a dialysis machine that removes the #SARSCoV2 coronavirus from the blood - FDA has approved it for emergency use. It has been used to treat nearly 300 patients. #COVID19
2) Dr. Matt Hepburn: This is a filter that you can put on a dialysis machine.
"Patient 16", a military spouse, was in the ICU, near death with organ failure and septic shock when she was entered into a Defense Department COVID-19 study (video above)

cbsn.ws/3237WqI
3) Dr. Gaeta: She's liberated from veso-active medications and her septic shock resolved. We also see improvements in her markers of inflammation. Those are all positive prognostic signs.

Bill Whitaker: You pass someone's blood through this--
Read 11 tweets
12 Apr
The most important vaccine in Latin America—SinoVac’s CoronaVac reports new trial results from Brazil 🇧🇷—

Efficacy against symptomatic #COVID19–50.7%. Moderate & severe: 83.7% / 100%. Delayed 2nd dose no issue. Neut. titres lower in age>=60 against #P1.🧵
papers.ssrn.com/sol3/papers.cf… Image
2) Results 12,396 people randomized in Brazil. It seems 2nd dose efficacy wasn’t much diff than 14 days after 1st dose. And delaying 2nd dose didn’t seem to hurt. And a second dose >21 days actually showed no drop in efficacy. ImageImage
3) As for lab antibody neutralization titres, vaccinated people had no real difference for seroconverting (having antibodies) against different variants. That said, among those who seroconverted, neutralization titres was lower among those age 60 and above against #P1 🇧🇷 variant. Image
Read 18 tweets
11 Apr
What’s worse than losing school days during pandemic? Losing a parent.

Nearly ~40,000 children have lost a parent to #COVID19, black children even more.
"The number of children experiencing a parent dying of Covid-19 is staggering.”

cnn.com/2021/04/05/hea…
2) "Black children are disproportionately affected, comprising only 14% of children in the US but 20% of those losing a parent to Covid-19."
3) “The model suggests that each Covid-19 death leaves 0.078 children aged between 0 and 17 parentally bereaved, representing a 17.5% to 20.2% increase in parental bereavement absent of Covid-19”
Read 12 tweets
11 Apr
My god India 🇮🇳... and it’s not just more testing, because positivity had quintupled (5x) in recent month. India could be the next Brazil 🇧🇷 in terms of #COVID19 crisis scale. Image
2) India crisis is also due to mixed messages and complacency, writes @AmyKazmin.

“Mixed messages from the prime minister and health authorities left the public playing down the risk of the virus”
3) I hope people realizes how important India is... it’s also the world’s largest maker of vaccines for COVID. But it recent halted all exports due to this surge. Hence Canada 🇨🇦 is now delayed in its vaccine deliveries due to the crisis there in India. amp.ft.com/content/6f6705… Image
Read 7 tweets

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