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Krutika Kuppalli, MD FIDSA Profile picture
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14 Apr, 8 tweets, 3 min read
1/
Information regarding the six patients who have developed CVST after the #JohnsonandJohnson #CovidVaccine
- All were white females
- Only one was on oral contraceptives
2/ Clinical features of the patients
3/ Location of CVST
4/ All patients were #COVID19 Negative
5/ All patients had thrombocytopenic and 5/6 had a PF4 HIT Ab positive
6/ At this time, 1 has died, 3 remain hospitalized, 2 discharged home
7/
8/
Take Home Messages
- CVST is a rare event
- All patients had thrombocytopenia and positive PF4 Ab
- All patients were COVID-19 Negative
- Does not appear to be any patterns or risk factors
- If concern that patient has CVST should check PF4 Ab and consult with hematology

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More from @KrutikaKuppalli

Krutika Kuppalli, MD FIDSA Profile picture
10 Jan
Thoughts on #CovidVaccine Rollout

I see a lot of suggestions/posts about #vaccine rollout and since I have been involved with this thought I would provide insight based on my experiences

See thread below 👇

1/
1. Expecting our hospitals/healthcare systems to absorb the #CovidVaccine rollout without support is unreasonable.

- Hospitals are running on empty and short staffed trying to manage caring for patients
- Rolling out this vaccine takes a lot of support and planning

2/
2. The lack of federal coordination is making this increasingly complex

- Each state has its own plan and within each state each hospital has its own plan
- There is no uniformity
- This leads to disparities between and within states

3/
Read 9 tweets
Krutika Kuppalli, MD FIDSA Profile picture
13 Dec 20
Since I am helping lead the #Pfizer #CovidVaccine rollout at our institution I have spent a lot of time doing town halls and engaging with people on the vaccine.

One of the most common questions I get is in regards to side effects so I thought I would post my slides
Overall localized side effects of the #CovidVaccine
Overall systemic side effects of the #CovidVaccine
Read 4 tweets
Krutika Kuppalli, MD FIDSA Profile picture
7 Nov 20
I want people to understand what we mean when we say that hospitals are at "capacity"

- That means there are no more beds for patients
- If you are in a trauma and need care there is not a bed
- Your elective surgery cardiac cath, or biopsy is will be postponed
- When you come to the Emergency Room you are going to wait much longer because doctors and nurses are busy trying to manage all the patients
- You may have to stay in a bed in a hall (if you are lucky)
- Nurses will be further stretched and have less time to tend to you
- It will take longer to get your x-ray, blood draws, and any other tests you need
- Doctors will have more patients to take care of and are unable to spend as much time thinking about your care

Normally we would be able to get backup from other areas, but not in a pandemic
Read 4 tweets
Krutika Kuppalli, MD FIDSA Profile picture
7 Nov 20
Given the #surge of #COVID19 in the US we need to focus on containing the pandemic. Here are some things we need
1. We need a #NationalPlan to combat this infection
- Right now we have 50 states doing 50 different things
2. Scale up testing
- Use of PCR, saliva, rapid, Ag
1/
3. Focus on community engagement at the local, state, and national level
- Empower communities and people to be proactive
4. Statewide #MaskMandates
5. Limitations on crowd and gathering sizes
6. Support of I&Q
- Paid sick leave, mental health, and healthcare
-Food delivery
2/
7. Scale up of contact tracing once we get case counts lower
8. Support for public health departments and schools so they can carry out recommendations
9. Support for heathcare workers who are burned out
10. Scale up PPE production
11. Financial support for small businesses
3/
Read 4 tweets
Krutika Kuppalli, MD FIDSA Profile picture
3 Aug 20
This statement made concerns for a "October surprise" alive and well. I can't believe I am typing words that say we may have a #vaccine for the greatest public health tragedy of the modern day that may not be vetted through the @US_FDA advisory panel of experts.
The continued politicization of this pandemic is a grave danger to the health and wellbeing of not just the public but to the very foundation of our democracy. I keep saying we need to let science lead and that is no where more true than with the development of a #vaccine.
Developing a safe and efficacious #vaccine is paramount to having the public uptake this important intervention. If there is perception science has been "skipped" over then we have already defeated ourselves out the door.

People will not get a vaccine that doesn't appear safe.
Read 4 tweets
Krutika Kuppalli, MD FIDSA Profile picture
27 Jul 20
I recognize that $22,200,000,000 a year to prevent a pandemic sounds astronomical, but honestly we should have been proactive and been doing this way before the #SARSCoV2 pandemic. We have had numerous warning signs over the years this was coming and did not take them. (1/9)
We have seen re/emerging infections increase over the past 40 years. We have had SARS, MERS, Zika, and numerous Ebola outbreaks as warnings this was coming. Yes we did invest after the 2014 W Africa outbreak but it was not on the scale needed to prevent, prepare, for this (2/9)
Look at the world right now, in addition to the #COVIDー19 pandemic we have ongoing outbreaks of Ebola, measles, cholera, plague, monkeypox, drug resistant typhoid along with others being battled which could become a regional epidemic or evolve into a pandemic as well. (3/9)
Read 9 tweets

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