@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden Regarding India, I first noted in July 2020 that we would eventually see bad news due to comorbidites (in the context of poverty and inequality), but that overall deaths per capita would be limited by the low population age - similar to current events

@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden It is a tragedy, in the sense of the "remorseless working" of well-understood factors underlying public health in general, e.g. poverty

India spends <$30 AUD per capita on health

Australia spends >$7000 per capita
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden Few people cared about the inequitable infectious disease burden in poor countries until it became fear pornography in the media

I have written, for example, about how deaths due to drug resistance are massively underestimated in countries like India

link.springer.com/chapter/10.100…
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden Life expectancy in India is ~69 years, and many people die with poor health for multiple reasons

Worse still, young people die of drug resistant infections and tuberculosis en masse

E.g. ~50,000 newborns of resistant sepsis per year

sciencedirect.com/science/articl…
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden In this context, I know #covid19 seems more urgent, but it remains a disease that mainly kills older members of the population (India vs. US data below, from July 2020)

medrxiv.org/content/10.110…
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden My own view is that public health should aim to maximize public health, broadly conceived and in the long term

Short term thinking often harms public health in the long term, and India has many public health issues that will outweigh #covid19 in the long term
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden I find it particularly unacceptable when commentators:

- racialise #covid19 (e.g. Indian double mutant)

- claim that poor countries are a melting pot for dangerous variants that could harm rich countries

- claim that #zerocovid was ever a realistic strategy in India
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden Despite the enormous death toll in India, the country is not even in the top 50 in terms per capita deaths

This is not to minimize the awful human consequences, but to put them in context, which is difficult when watching current news reports

statista.com/statistics/110…
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden Meanwhile, Indian children have been out of school for over a year

Child marriages have dramatically increased due to the response to #covid19

This is is a long term public health catastrophe on a massive scale

@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden I strongly support global action by rich countries to support poor countries, but not just for #COVID19 - we should focus on helping improve global public health in the long term

In my view, we should also prioritize children, who have their whole lives ahead of them
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden We should not focus on providing things like ventilators for the current crisis, which might sound like a good idea, but will achieve little benefit - among other things due to lack of staffing and resistant bacterial ventilator-associated pneumonia
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden On lack of staffing, there is an enormous "brain drain" of many (though by no means all) Indian scientists, doctors, and nurses who move to rich countries for a better life after being educated in India

This, too, is a tragedy - and by no means the fault of these individuals
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden On #covid19, if we had to pick one intervention, it would be providing vaccines to older people or those with commodities everywhere in the world - rather than vaccinating young healthy people in richer countries before older people in poorer countries

This was predictable.
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden The spread of the false and unscientific message that young healthy people face high risks due to #covid19 arguably undermined global equitable vaccine provision, especially once effectiveness in risk groups was known.

This, too, was a predictable tragedy.
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden As I mentioned earlier, India spends around 1,600 rupees (<$30) per capita on health/year

A #covid19 test often costs over 1,000 rupees

Think about what appropriate long-term health resource allocation would look like for these >1.3 billion human beings

indianexpress.com/article/india/…
@COVID_questions @bergerbell @pgodfreysmith @NahasNewman @WesPegden I am done talking about India for now, suffice it to say that I think we should prioritize:

- the whole of public health > one cause of harm
- long term > short term
- children > older adults
- global mutual aid > fearmongering & xenophobia
- science > magical thinking

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Infectious Disease Ethics

Infectious Disease Ethics Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @ID_ethics

2 Mar
1/ We reviewed Australian medical guidelines:

Some medical decisions are evidence-based, but many are not - and this varies by specialty

E.g., Australian antibiotic guidelines do not state the level of evidence for recommendations (which is often low)

onlinelibrary.wiley.com/doi/full/10.11…
2/ Previous reviews of American Infectious Diseases Guidelines found that only 14% of recommendations were based on the highest level of evidence

jamanetwork.com/journals/jamai…
3/ One problem with a lack of evidence is that it leads to overtreatment:

Many antibiotic courses are longer than they need to be - sometimes because shorter courses haven't been tested in randomized trials

jamanetwork.com/journals/jamai…
Read 4 tweets
25 Feb
Post-lockdown rebound of infectious diseases:

RSV is back in Australia with a vengeance - current cases in red below, usual incidence in black

Note that #RSV is far more dangerous to infants & young children than #covid19

academic.oup.com/cid/advance-ar…
To get a sense of #RSV vs. #covid19 in children:

In the UK:

- #RSV : usually kills 28-79 children per year

- #covid19 : a total of 7 children had died in paediatric intensive care up to November 2020

RSV data: jech.bmj.com/content/59/7/5…
covid19 data: picanet.org.uk/covid-19/
Post-lockdown rebound of #RSV will also harm adults, especially older adults:

RSV usually causes ~10,000 deaths per year among US adults aged >65

RSV in nursing homes has a fatality risk of 2-5%

Imagine if incidence doubles, as it has in Australia?

ncbi.nlm.nih.gov/pmc/articles/P…
Read 6 tweets
23 Feb
Article title: coronavirus immunity is "short-lasting"

Article figure: median time to re-infection ~ 2.5 years

(Median = black vertical line below)

Most people would be happy with >2 years to reinfection, especially with reduced clinical severity...

nature.com/articles/s4159…
The above is an example of how scientists and journal editors could better communicate findings and risks

The widespread and baseless fears that there would not be immunity to #covid19 could have been reduced, rather than increased, by more careful reporting of the same data
From the same study:

~50% of people infected with endemic coronaviruses still have higher levels of antibodies after 4 years

No reason to think that #covid19 would be wildly different

(antibodies don't necessarily = clinical protection, but still good data)
Read 5 tweets
26 Jan
Terminology thread:

rate ≠ risk
infection ≠ disease
quarantine ≠ isolation
social distancing ≠ physical distancing
prolonged PCR positivity ≠ shedding
virulence ≠ transmissibility

References to follow
1/ rate ≠ risk

A risk is a probability of a harm (of a given magnitude)

A rate is something that varies over time

journals.lww.com/epidem/Fulltex…
2.1/ infection ≠ disease

Many infections are asymptomatic or even beneficial!

An infectious disease only occurs when the host-pathogen interaction results in harm (i.e., a harmful disturbance of normal host function)

link.springer.com/article/10.100…
Read 10 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!