1. In a bid to boost demand for shots, Sisonke investigators have widened the criteria for eligible #HealthWorker participants this week, opening the way for researchers, lab staff, care workers, health agency staff + medical schemes to get vaccinated. bit.ly/3tGpZOE
2. Glenda Gray, co-lead Sisonke investigator: “The two-week [Sisonke] pause caused a lot of vaccine hesitancy. We were concerned that ... sites were closing at 2pm or 3pm and doing only a few hundred people a day.” bit.ly/3tGpZOE
3. Sisonke vaccinated 18 000+ people on Tu - the highest nr since the start of the trial. Glenda Gray, co-lead investigator: “We have to close ... before the national roll-out commences. It would be a logistical nightmare [to run the two concurrently]." bit.ly/3tGpZOE

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More from @miamalan

13 May
[Thread] 1. Why did the #Sisonke trial researchers broaden the definition of #HealthWorkers who can get vaccinated and are people using it to jump the queue (so are non-health workers queuing up to get vaccinated)?
2. The #JandJ doses for the #Sisonke study are research doses specifically donated to vaccinate trial participants (#HealthWorkers). The trial ends on 15 May and unused doses would have to be returned to J&J.
Source: Keith Cloete, WC health dpt Image
3. Because #Sisonke doses can only be used for the trial, leftover doses can't be given to Phase 1B (#HealthWorkers not covered by Sisonke) or Phase 2 (people of 60+) of the roll-out. Sisonke either has to use the doses/return leftover ones.
Source: Keith Cloete, WC health dpt
Read 11 tweets
13 May
[Thread] 1. VACCINE ROLL-OUT UPDATE from the Western Cape: Keith Cloete, the head of the WC health department says the province today received just over 30 000 doses of the 1st batch of (325 260) Pfizer #CovidVaccines that arrived in SA on May 2. Image
2. .@WestCapeHealth expects to receive #JandJ jabs from May 28. Deliveries of both #Pfizer + J&J will be made each week (the nr of doses will increase with time — in line with national deliveries: SA will get 300 000 Pfizer doses each week in May and 600 000+ each week in June).
3. What will the 30 000 #Pfizer jabs in the WC be used for? To vaccinate #HealthWorkers not covered by the Sisonke trial and people of 60+ in old-age homes. So phase 2 (people of 60+) will start off in old-age homes, not at individual sites. When? Monday, 17 May.
Read 9 tweets
12 May
[Thread] 1. LATEST on #COVID19SA cases:
1. There was a 46% increase in new cases when the weeks of April 26th + May 3rd are compared.
2. Cases in all provinces increased in the last 7 days:
- Northern Cape: 68%
- Gauteng: 63%
- Limpopo: 47%
- North West: 42%
- Western Cape: 39% Image
2. #Covid19SA deaths increased by:
* 18.22% when the weeks of April 26th and May 3 are compared
* But when the last 14 days are compared, deaths decreased by about 30%
* KZN and the Western Cape account for 8 out of every 10 reported deaths Image
3. What about #HealthWorkers?
- They constitute 3.51% of all reported #COVID19SA cases
- Since the start of the pandemic, just over 56 000 have tested positive (there were 25 cases in the past 7 days)
- 874 health workers have died (1.56% of all cases) Image
Read 6 tweets
2 May
[Thread] 1. Just before midnight on Sunday, SA will receive its first batch of commercial #CovidVaccines: 325 260 #Pfizer doses (enough to fully vaccinate 162 630 people - each person needs 2 doses).
2. A small study of 800 people has shown that the #Pfizer jab is 100% effective in protecting against falling ill with #COVID19 in SA (the trial was conducted while the #501YV2 variant was the most common form of the #COVID virus circulating in SA). bit.ly/3eReBtU
3. What will happen to the #Pfizer doses when they touch down at OR Tambo? They'll be transported to a central warehouse. Samples of the doses will then be selected and transported to Bloemfontein to the National Control Lab so they can be tested for quality.
Read 10 tweets
26 Apr
[Thread]. 1. This morning @ZweliMkhize announced that the Sisonke trial, which uses #JohnsonandJohnson’s #COVID19 jab, will resume on Wednesday. So what happens now?
2. Up until now, the Sisonke trial has vaccinated about 300 000 #HealthWorkers. @SAHPRA1 paused the trial in April, after the FDA/CDC in the US temporarily halted its #JandJ roll-out due to the occurrence of 8 rare blood clotting disorders among about 7 million vaccinated people.
3. None of the blood clots that occurred in the US, occurred in SA's Sisonke trial (likely because it’s so rare and we’ve only vaccinated about 300 000 people vs. the US’s 7 mil). The US unpaused its #JandJ roll-out on Fri after the FDA cleared the jab. bit.ly/2PsRgGA
Read 19 tweets
22 Apr
[Thread] 1. Just in from Wednesday's cabinet briefing:
* The #CovidVaccine roll-out is still scheduled to start on May 17.
* There are now 3 338 vaccination sites (a list with the names hasn't been released).
2. When will can we start to use the 31 million #JohnsonandJohnson jabs that we've bought and will the first 1 million (from Aspen in SA) still land this week? We don't know. Neither @SAHPRA1 (our regulator; it needs to authorise use) nor @healthZA have made an announcement.
3. What do we know? Sahpra has recommended that the Sisonke trial (it uses J&J jabs) should resume. But before that can happen, Sahpra has to approve new docs submitted by the researchers (the study has to adhere to new rules set by Sahpra, e.g. better screening for blood clots).
Read 8 tweets

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