Discover and read the best of Twitter Threads about #JandJ

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[Thread] 11. LATEST #VaccineRolloutSA figures:
1. The total nr of #JandJ + #Pfizer 1st (of 2) shots by Wed: 1 193 352
2. Nr of #Pfizer shots on Wed: 1 193 352 - 1 117 569 = 75 783 (on Tue 72 456 shots were given).
3. Total nr of Pfizer shots: 637 801 (Wed) + 75 783 = 713 584
2. Can we do more than +/- 75 000 shots/day?
@HealthZA's Nicholas Crisp says no, not until we get our #JandJ jabs (or additional Pfizer/other brands). Why? Otherwise we run the risk of using up the jabs before the next #Pfizer batch arrives, and will have to stop and start.
3. How many #Pfizer jabs have we got?
* By Jun 1 we had 1,937,520 doses
* Of the 1,937,520 doses, 1,294,020 have been distributed to sites (we had used 713 584 of the 1,294, 020 by Wed)
* The batch of 636,480 of 31 May is still under quarantine
* Next batch: 636 480 on 7 Jun
Read 5 tweets
[Thread] 1. When will we hear if Aspen can release SA’s #JandJ jabs from their Gqebera plant and why can’t the country itself just give the go ahead? @healthza’s Nicholas Crisp says the #FDA has told him they’ll make an announcement on Fri (tomorrow).
2. The FDA can decide:
1. Our #JandJ jabs haven’t been contaminated + can be released.
2. Some batches are fine, some not. Only some can be released.
2. All jabs = contaminated +can’t be used.
3. Our jabs can't be used the US, but Sahpra can decide if we can use them in SA.
3. Why is the #FDA making this decision and not SA? Because Aspen has a contract with #JandJ and a US factory which manufactured the key ingredient (API) for our jabs is being investigated by the FDA.
Read 10 tweets
[Thread] 1. SUNDAY #VaccineRolloutSA figures:
* Total #Pfizer doses by end of Sun: 490 680 (everyone still needs a 2nd shot, 42 days after the 1st one)
* Pfizer doses given on Sun: 2 129
* Pfizer doses from 24 May (Mo) - 30 May (Su): 318 820 (vs. the previous week's 171 860)
2. What's the total number of #CovidVaccinations we've done so far?
* #Pfizer: 490 680 (these people aren't fully vaccinated, they still need second shots)
* #JandJ (via #Sisonke): 479 768 (these #HealthWorkers are fully vaccinated)
* Total nr of Pfizer and J&J shots: 970 448
3. How many #Pfizer doses do we have? @healthza's Nicholas Crisp says:
- 1.3 mil have been distributed to sites
- We had used +/- 500 000 by Sun, so we had +/- 700 000 left
- We got 636 000 more on Mon. They can only be used in a wk's time after quality testing had been done
Read 5 tweets
1. #CyrilRampahosa: 67% of health workers have been vaccinated. IN total: 960 000 people in SA have received 1 #COVID vaccination dose (either #Pfizer or #JandJ). Over the next days, we would have administered 1 vaccination dose to more than 1-million of the most vulnerable SAs.
2. #CyrilRampahosa: SA has secured enough vaccines to cover all adults:
* 31 million #JandJ doses (this is a single dose jab)
* 20 million #Pfizer doses (this vaccine requires two doses, 42 days apart)
3. #CyrilRampahosa: SA's #JandJ jabs have been delayed because of a lack of adherence to proper standards at a US factory. We're waiting for these issues to be resolved before our J&J jabs can be released from Aspen in EC. We are in constant contact with the relevant authorities.
Read 5 tweets
[Thread] 1. Is #VaccineRolloutSA moving fast enough to consume the jabs that SA will receive over the next 5-6 weeks? To answer that, we need to look at how many jabs we’ll have and how many daily vaccinations we would need to do to use the shots.
2. How many jabs will we (likely) have for the next 5-6 weeks?
* Business SA on Fri said we'll have 3 mil #JandJ doses by the end of June (if the FDA authorises the release of the jabs in time)
* 4.5 mil #Pfizer doses by the end of June (#Mkhize announced this in May)
3. Business SA/health dpt calculated:
* For the wk of May 17 we needed to do 54 200 vaccinations/day
* For the wk of May 24 we need to do 109 200 vaccinations/day
* For the other weeks until the end of June we need to do 192 500 vaccinations/day
(this is based on 6 days/wk)
Read 19 tweets
[Thread]. 1. How many #CovidVaccine doses has #VaccineRolloutSA administered so far?
1. 480 665 (#Sisonke, #JandJ) + 77 505 (Phase1B and #Phase2, #Pfizer) = 558 170
2. NB: For Pfizer the 77 505 are just the 1st of 2 doses, so those people have not yet been fully vaccinated.
2. The number of people getting their 1st #Pfizer dose today = 38 134. That means in one day (Wed) we vaccinated as many people as in the previous two days (Mon + Tu = 39 371), so we're picking up speed.
3. The total number of #Sisonke #CovidVaccinations has increased by 897 (from 479 768 to 480 665), probably because of final vaccination data that was coming in after the trial had ended.
Read 3 tweets
[Thread] 1. #ZweliMkhize: The Sisonke programme is now finished. 478 733 doses of 500 000 doses were used. The leftover doses will be used by the SAMRC to conduct studies (HIV, people with comorbidities, pregnant women, etc). The doses can't be used for Phase 2.
2. #ZweliMkhize: We will receive another just over 300 000 #Pfizer doses by tomorrow morning. This will bring our total number of #Pfizer doses to 975 780.
3. #ZweliMkhize: We will have vaccinated 5 million people by the end of June, provided that the vaccine supply flow as anticipated. By the end of June we will have 4.5 million #PFizer doses and 2.2 #JandJ doses.
Read 8 tweets
[Thread] 1. What can a #CovidVaccine site (e.g. Dischem) charge for? This health dpt memo, that was sent to providers + published by B4SA (businessforsa.org/wp-content/upl…), says:
* #Pfizer: R354.75 (R308,48 + VAT) per dose
* #JandJ: R330.00 (R286,96 + VAT) per dose
* R70 admin fee/dose
2. The #CovidVaccines arrive at sites in multi-dose vials. What do these cost?
* #Pfizer (you need 2 doses, 21 days apart): There are 6 doses in a vial, so a vial costs R1 850,88 [without VAT]
* #JandJ: There are 5 doses in a vial; so a vial costs R1 434,80 [without VAT]
3. Can a provider ask you to pay for the R70 #CovidVacine administration fee at the counter? NO. They have to bill your medical aid (if you're insured) or the government (if you're not insured) directly.
Read 5 tweets
[Thread] 1. Why did the #Sisonke trial researchers broaden the definition of #HealthWorkers who can get vaccinated and are people using it to jump the queue (so are non-health workers queuing up to get vaccinated)?
2. The #JandJ doses for the #Sisonke study are research doses specifically donated to vaccinate trial participants (#HealthWorkers). The trial ends on 15 May and unused doses would have to be returned to J&J.
Source: Keith Cloete, WC health dpt
3. Because #Sisonke doses can only be used for the trial, leftover doses can't be given to Phase 1B (#HealthWorkers not covered by Sisonke) or Phase 2 (people of 60+) of the roll-out. Sisonke either has to use the doses/return leftover ones.
Source: Keith Cloete, WC health dpt
Read 11 tweets
[Thread] 1. VACCINE ROLL-OUT UPDATE from the Western Cape: Keith Cloete, the head of the WC health department says the province today received just over 30 000 doses of the 1st batch of (325 260) Pfizer #CovidVaccines that arrived in SA on May 2.
2. .@WestCapeHealth expects to receive #JandJ jabs from May 28. Deliveries of both #Pfizer + J&J will be made each week (the nr of doses will increase with time — in line with national deliveries: SA will get 300 000 Pfizer doses each week in May and 600 000+ each week in June).
3. What will the 30 000 #Pfizer jabs in the WC be used for? To vaccinate #HealthWorkers not covered by the Sisonke trial and people of 60+ in old-age homes. So phase 2 (people of 60+) will start off in old-age homes, not at individual sites. When? Monday, 17 May.
Read 9 tweets
[Thread] 1. Just before midnight on Sunday, SA will receive its first batch of commercial #CovidVaccines: 325 260 #Pfizer doses (enough to fully vaccinate 162 630 people - each person needs 2 doses).
2. A small study of 800 people has shown that the #Pfizer jab is 100% effective in protecting against falling ill with #COVID19 in SA (the trial was conducted while the #501YV2 variant was the most common form of the #COVID virus circulating in SA). bit.ly/3eReBtU
3. What will happen to the #Pfizer doses when they touch down at OR Tambo? They'll be transported to a central warehouse. Samples of the doses will then be selected and transported to Bloemfontein to the National Control Lab so they can be tested for quality.
Read 10 tweets
[Thread]. 1. This morning @ZweliMkhize announced that the Sisonke trial, which uses #JohnsonandJohnson’s #COVID19 jab, will resume on Wednesday. So what happens now?
2. Up until now, the Sisonke trial has vaccinated about 300 000 #HealthWorkers. @SAHPRA1 paused the trial in April, after the FDA/CDC in the US temporarily halted its #JandJ roll-out due to the occurrence of 8 rare blood clotting disorders among about 7 million vaccinated people.
3. None of the blood clots that occurred in the US, occurred in SA's Sisonke trial (likely because it’s so rare and we’ve only vaccinated about 300 000 people vs. the US’s 7 mil). The US unpaused its #JandJ roll-out on Fri after the FDA cleared the jab. bit.ly/2PsRgGA
Read 19 tweets
1/ Breaking news: Federal officials hit the pause button on #JohnsonandJohnson vaccine.

Giving themselves runway to perform all appropriate due diligence, the @US_FDA & @CDCgov have called for a temporary pause in the use of the #JandJ vaccine. Image
2/ Their diligence will analyze the cases of 6 U.S. women who developed very rare blood clots after receiving the J&J vaccine. Nearly seven million people have received this vaccine to-date in the U.S.
3/ Clinical notes:

All 6 events happened in women ages 18-48. All happened within three weeks post-vaccination. The pause is specific to the #JohnsonandJohnson vaccine, & not the #Pfizer & #Moderna vaccines.
Read 8 tweets

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