⚠️“dramatic rise in UK cases of a variant first discovered in India could undermine roadmap for reopening”, scientists caution. One of 3 key 🇮🇳variants, #B161712, now surged to 6% of all variants in UK, WHO & England both upgraded to “variant of concern”.🧵theguardian.com/world/2021/may…
2) Prof @chrischirp, of University College London and member of @IndependentSage experts, speaking in a personal capacity said rise in B.1.617.2 cases was concerning enough to delay the next stage of the roadmap scheduled for Monday, when a range of restrictions are to be lifted.
3) “the second most common variant in the UK. Wellcome Sanger Institute’s Covid-19 genomic surveillance data – **which excludes recent travellers and surge testing specimens** – suggests about 6.1% of Covid genomes in England sequenced in the 4 weeks to 24 April are B.1.617.2.
4) While the Kent variant is decreasing or stabilising, B.1.617.2 is flourishing. In some parts of the country, such as Bolton and Blackburn the variant accounts for over 50% of cases.
5) Pagel pointed out that, while B.1.617.2 numbers are not currently that big, they are doubling every week – and this is all within the space of three weeks.
6) “We’ve done this so many times – waited until things got really bad before we realised we should have acted several weeks ago,” she said. “So why don’t we actually act several weeks ago – which is now!” @chrischirp says.
7) “On Thursday, leaked Public Health England documents seen by the Guardian showed that 48 clusters of B.1.617.2 had been identified, including those linked to secondary schools, care homes and religious gatherings.” theguardian.com/world/2021/may…
8) there are now new analysis that show #B16172 is 2x faster transmission than even the faster #B117! And it will likely take over as the dominant strain in the UK in coming month or two.

9) And again, these @sangerinstitute genomic data excludes travel import cases and excludes aggressive surge testing cases!
10) some say 6% still low (some say it’s over 11% now, and over 50% in some cities in UK), but don’t forget the power of exponential growth. It start slow but can soon compound.
11) #B1617 family of lineages are now surging worldwide. And it’s clearly outpacing other variants. Ht @trvrb
12) Don’t dare say Indian #B16172 variant isn’t alarming. Keep in mind the UK is also heavily vaccinated too.
13 really bad trajectory of #B16172 India 🇮🇳 variant in England 🏴󠁧󠁢󠁥󠁮󠁧󠁿
14) Even wealthy Singapore also being hit by #B1617 variant.
15) Scotland is heavily vaccinated… yet…

We need over 90% vaccinated I think given how contagious #B1617 is.

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More from @DrEricDing

14 May
⚠️BREAKING—Singapore 🇸🇬 returning to lockdown mode for one month as #COVID19 cases rise, many #B16172 variants. Indoor dining suspended immediately. Travel bubble with HK🇭🇰 now unlikely. 31% of Singaporeans have >=1 shot, 22% fully vaccinated. Still surge.
bloomberg.com/news/articles/… Image
2) 🇸🇬 is returning to the lockdown-like conditions it last imposed a year ago, banning dining-in and limiting gatherings to two people, as a rising number of untraceable virus infections pressures one of the most successful places in the world at Covid containment.

➡️YET STILL!
3) “A pattern of local unlinked community cases has emerged and is persisting,” the statement said. “We need to act decisively to contain these risks as any one leak could result in an uncontrolled resurgence of cases.”
Read 7 tweets
14 May
Familiar? 80 years ago—one man (Wells) discovered viruses were airborne & UV light led to fewer sick kids. He was dismissed at the time—by chief epidemiologist of the CDC. The CDC panned the idea measles was airborne for many decades. They were dead wrong.
wired.com/story/the-teen… Image
2) The distinction between droplet and airborne transmission has enormous consequences. To combat droplets, a leading precaution is to wash hands. To fight infectious aerosols, the air itself is the enemy. In hospitals, that means expensive isolation wards and N95 masks for all.
3) “The books @linseymarr flipped through drew the line between droplets & aerosols at 5 microns. A micron is a unit of measurement equal to one-millionth of a meter. By this definition, any infectious particle <5 microns in diameter is an aerosol; bigger is a droplet.”
Read 44 tweets
14 May
FACT: Asymptomatic cases can still spread the coronavirus to someone vulnerable.

Vaccinate but still try to protect others who cannot / unable / unwilling (yes, let’s protect them too). #COVID19 #empathy Image
2) But homes, schools, and businesses are not HBO TV show sets with unlimited testing budgets. How many transmissions will there be if we ditch masks too early? variety.com/2021/tv/news/b…
3) We also aren’t rich like the Yankees— 8th member, shortstop Gleyber Torres, is positive for #COVID19 in latest team outbreak. All 8 members are fully vaccinated, thus “breakthrough positives.” Too early to ditch masks. Think of others not vaccinated yet.forbes.com/sites/joshuaco…
Read 4 tweets
14 May
Bill Maher has tested positive for #COVID19. HBO says he was “fully vaccinated”. HBO insists he “feels fine”, yet was forced to scrap Friday’s scheduled taping of @RealTimers.
variety.com/2021/tv/news/b…
2) To be clear—I am absolutely for vaccinations. But homes, schools, and businesses are not HBO TV show sets with unlimited testing budgets. How many transmissions will there be if we ditch masks too early?
3) NY Yankees announced 8th member, shortstop Gleyber Torres, is positive for #COVID19 in latest team outbreak. All 8 members are fully vaccinated, thus “breakthrough positives.” Plus, Torres had Covid in Dec 2020, so also a reinfection. By @JoshuaPCohen1
forbes.com/sites/joshuaco…
Read 4 tweets
13 May
Not pleased at all—In a sharp turnabout from previous advice, CDC on Thursday said fully vaccinated may stop wearing masks or maintaining social distance in most indoor and outdoor settings, regardless of size, regardless of others.

Too early. #COVID19
nytimes.com/2021/05/13/hea…
2) This is too risky in my opinion. asymptomatic transmission efficacy is only in the 70s-80s even for the best vaccines. Much lower for others and for some variants.
3) “Walensky's announcement have a few caveats. She warned that people who are immune compromised should speak with their doctors before giving up their masks.”
Read 18 tweets
13 May
📍My god… the upgraded warning #B16172 variant (magenta) is surging so fast. Epidemiologists now estimate it is 60% faster than even #B117 UK/Kent variant, which is already 50% faster. If true, it could make it fastest transmission one to be found worldwide. Thread 🧵. #COVID19 Image
2) #B1672 has become quite dominant in India 🇮🇳 sequenced samples in @GISAID data. And it is projected to take over further by June. Figure from @TWenseleers.

Some say it could be due to sampling, but Tom doesn’t think so because #B16171 wouldn’t be selectively withheld. Image
3) @TWenseleers used his methods from earlier paper to estimate the new #B16172 transmission being 60% fast than the U.K. Kent #B117 variant.
Read 13 tweets

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