⛓️Let's talk about vaccine supply chains! (yay!) 💉🌍✌️
If we are to make 11bn doses of vaccine this year, there is an urgent need to address supply chain issues or we will not be able to make all these doses. 🧵
If we are to make 11bn doses of vaccine this year, there is an urgent need to address supply chain issues or we will not be able to make all these doses. 🧵
⛓️Recap: in March many firms in the sector met at Chatham House and talked about their concerns over vaccine supply chains.
At the time there were no stated impacts on covid vaccines but the signs were ominous. (Problems on lines that make drugs using the same equipment.)
At the time there were no stated impacts on covid vaccines but the signs were ominous. (Problems on lines that make drugs using the same equipment.)
⛓️Concerns were focused on, but not limited to, America's use of the Defense Production Act which was already having a knock-on impact on lead times for key ingredients.
⛓️Then April 15th @adarpoonawalla of @SerumInstIndia tweeted a plea @POTUS.
I wrote about this the next day, explaining that the...
💉@AstraZeneca & 🇮🇳
💉@Novavax lines were threatened and that 37 items had been requested from the US government. 🇮🇳
I wrote about this the next day, explaining that the...
💉@AstraZeneca & 🇮🇳
💉@Novavax lines were threatened and that 37 items had been requested from the US government. 🇮🇳
https://twitter.com/adarpoonawalla/status/1382978713302683653?s=20
⛓️(This piece was updated for print on 22nd and now appears online as this piece.)
economist.com/science-and-te…
economist.com/science-and-te…
⛓️Since then there has been more news. Lots of it.
May 4th: Germany 🇩🇪
💉@CureVacRNA the German maker of a promising new mRNA vaccine says its rollout is threatened by US export restrictions.
reuters.com/business/healt…
May 4th: Germany 🇩🇪
💉@CureVacRNA the German maker of a promising new mRNA vaccine says its rollout is threatened by US export restrictions.
reuters.com/business/healt…
⛓️May 7th: South Africa 🇿🇦
💉Biovac says it is short on biobags thanks to delays from its US supplier.
nasdaq.com/articles/insig…
💉Biovac says it is short on biobags thanks to delays from its US supplier.
nasdaq.com/articles/insig…
⛓️May 10th: Although the US has sent supplies to help the AZ line the...
💉@Novavax line in India has not been fixed and remains running at a fraction of its capacity. 🇮🇳
💉Another line in the UK has also been hit by shortages 🇬🇧
💉@Novavax line in India has not been fixed and remains running at a fraction of its capacity. 🇮🇳
💉Another line in the UK has also been hit by shortages 🇬🇧
https://twitter.com/natashaloder/status/1391881762926628867
⛓️May 12th: Brazil 🇧🇷
Two more lines hit by shortages:
@astrazeneca line in Brazil @fiocruz_en
@Sinovac line in Brazil @butantanoficial
Problems with one line also include delays in receiving items from China due to export controls there.
bloomberg.com/news/articles/…
Two more lines hit by shortages:
@astrazeneca line in Brazil @fiocruz_en
@Sinovac line in Brazil @butantanoficial
Problems with one line also include delays in receiving items from China due to export controls there.
bloomberg.com/news/articles/…
⛓️These problems are serious, appear to be getting worse, and are not going to vanish.
We need multilateral efforts between the US, EU, etc and firms in the sector.
We need multilateral efforts between the US, EU, etc and firms in the sector.
⛓️They also raise the question of whether vaccine makers that have come later, like @CureVacRNA, @Novavax are facing these restrictions at a critical time when they should be scaling up production?
And if all their 2021 output now needs to be adjusted downwards? 🤯
And if all their 2021 output now needs to be adjusted downwards? 🤯
⛓️They also make me wonder how the international scale-up of the J&J vaccine @JNJGlobalHealth is faring...
... and how a firm like @sanofi is going to obtain what it needs to scale up when it arrives.
... and how a firm like @sanofi is going to obtain what it needs to scale up when it arrives.
⛓️In short, are those 11bn doses even still realistic?
And I'm also wondering whether the vaccine makers themselves even know the answers right now?
Because I've been told that nobody really has good oversight of all the supply chains.
And I'm also wondering whether the vaccine makers themselves even know the answers right now?
Because I've been told that nobody really has good oversight of all the supply chains.
⛓️The industry is clear about what needs to happen.
All the trade and regulatory barriers need to be identified and governments need to work with @wto to ensure there are policies that expedite cross-border supply of key items.
For more see: ifpma.org/resource-centr…
All the trade and regulatory barriers need to be identified and governments need to work with @wto to ensure there are policies that expedite cross-border supply of key items.
For more see: ifpma.org/resource-centr…
⛓️Sort that lot out then let us talk about how an IP waiver is going to increase the vaccine supply........... 💉💉💉💉💉💉💉💉💉
⛓️ Paging: @GaviSeth @BroadGavin @CEPIvaccines @DrTedros @drrhatchett @PhRMA @EFPIA @IAmBiotech @ABPI_UK @VaccinesEurope @NathalieMoll
#VaccineShortage #VaccineEquality #VaccinesWork #vaccinate #India #brazil
#VaccineShortage #VaccineEquality #VaccinesWork #vaccinate #India #brazil
⛓️P.S. DM me with supply chain issues (customs, tariffs, or export controls) and production delays related to these. 💉🌏✌️
April 30th: Mexico 🇲🇽
This story reports that a Mexico 🇲🇽packing plant was unable to finish @AstraZeneca vaccine for Argentina 🇦🇷because of delays to the export of supplies from US. 🇺🇸 #supplychains
france24.com/es/minuto-a-mi…
This story reports that a Mexico 🇲🇽packing plant was unable to finish @AstraZeneca vaccine for Argentina 🇦🇷because of delays to the export of supplies from US. 🇺🇸 #supplychains
france24.com/es/minuto-a-mi…
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