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Eric Feigl-Ding Profile picture
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15 Jun, 13 tweets, 8 min read
BREAKING—CDC now officially declares #DeltaVariant a “variant of concern”—because much more transmissible (50% faster than #B117, 2x than original strain), more severe (2.5x hospitalization risk than B117, 4x original) & 1 dose vaccine evasive.🧵 #COVID19
cdc.gov/coronavirus/20…
2) This comes on the heels of the urgent advocacy by many to demand CDC upgrade to VOC. Even WHO and UK 🇬🇧 raised #DeltaVariant to VOC weeks ago. CDC is very late on this.
3) We have known #DeltaVariant has been rising fast in the Us for quite a while. Over a week ago, we already knew it was exponentially rising across the US. It’s doubling every 2 weeks overall, but doubling every week in certain states.
4) UK 🇬🇧 experts from @IndependentSage have been warning about #DeltaVariant for a while now too. Delta is now 90-96% to all new cases of #COVID19 in the UK.
5) UK scientists found #DeltaVariant to have 2.4-2.6x higher risk of hospitalization than B117 #AlphaVariant. But Alpha is 64% higher risk than original for hospitalization. So 1.6*2.5= 4.1x. That’s why we think Delta is 4x higher hospitalization than original.
6) Here is the biggest worry… that 1 vaccine dose isn’t sufficiently high enough protection anymore. Larger studies confirm this.
7) Why is the Delta variant so bad? How did it become a menace to the UK 🇬🇧 and the world? Here is how it snuck up on many countries.
8) #DeltaVariant can “take us back to square one” if we are not careful. We must not let it mutate out of control and evade vaccines further by letting it replicate and mutate more.

Watch video part 2 by @IndependentSage @VickiGSP
9) No one wants another lockdown damnit. But that is where it’s heading if we don’t act quickly with mitigation measures fast.
10) with #DeltaVariant you need two doses. Even Dr Fauci warns on this. 1 dose protection too low is a “problem”— much lower than than 2 doses. Vaccines work but we need two doses for sure.

As for the one dose J&J, I don’t have yet an official answer.
11) the UK, where #DeltaVariant is 90-96% of new cases, has some difficult times ahead. It’s a matter of how bad it can get… mitigation is now key. Vaccination surge will mostly mainly help those getting 2 doses.
12) the Delta variant’s contagiousness and risks of hospitalization explained here… how much more depends on whether compared to the previous #AlphaVariant B117 or the original.
13) Why nursing home staff don’t vaccinate is beyond me. Welp—More Florida nursing home residents are becoming infected with the virus. ➡️Only 42% of nursing home staff are even vaccinated in Florida! 🤦🏻‍♂️ FL asking for trouble.
tampabay.com/news/health/20…

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Eric Feigl-Ding Profile picture
17 Jun
Top question asked right now: what to do about J&J 1-shot #COVID19 vaccine & rise of #DeltaVariant? Not medical advice: lots of immunologists are hypothesizing & predicting mixing vaccines of different types could yield equal/better response. Trials TBD.🧵
bloombergquint.com/coronavirus-ou…
2) “If you can mix and match, it’s going to look better, something that immunologists have known for decades” said Danny Altmann, professor of immunology. “I’d bet my house on working hypothesis that it’s doable and would produce immunity that’s at least as good if not better.”
3) “After years of reading research on mixing vaccine types -- known as heterologous prime-boosting -- Morgon concluded that getting one dose of the AstraZeneca shot, and another from Moderna Inc.’s or Pfizer Inc.’s newer messenger RNA technology would pack the most punch.”
Read 9 tweets
Eric Feigl-Ding Profile picture
17 Jun
Jeez—an explosive 968% spike in #COVID19 in just one week—where the G7 Summit recently took place (and many security planners arrived 2 weeks ago). Is this related to the #G7Cornwall #G7Summit2021? Hmm, but a ~1000% increase is not something seen everyday.

HT @Dr_D_Robertson. Image
2) We can debate whether it’s because it started from a low base. But going up that fast is not normal at all. UK is very concerned about the spike there too. google.com/amp/s/www.bbc.…
3) Dr Ruth Goldstein said they were mainly Delta variant cases in under-30s.

Public health consultant, Dr Goldstein, said the rise was thought to be down to people from Cornwall travelling out and back during the school half-term break, as well as people coming in.
Read 10 tweets
Eric Feigl-Ding Profile picture
17 Jun
“Double wave” is coming—An internal NHS email sent to hospitals warn them to prepare for a 3rd #COVID19 wave with the 96% dominant #DeltaVariant - at the same time as a spike in serious infections among very young children. 🧵
channel4.com/news/hospitals…
2) The email, sent by a London NHS trust to clinical staff, says “national guidance on planning” has been issued telling hospitals to expect 50 per cent of the Covid cases seen in the first wave of the pandemic.
3) At the same time the third wave of severe Covid cases is likely to peak in hospitals, in early August, NHS leaders are also predicting a national wave of Respiratory Syncytial Virus or RSV infections.
Read 10 tweets
Eric Feigl-Ding Profile picture
16 Jun
Over 500 fully vaccinated tested positive for #COVID19 in Massachusetts in <3 weeks. As of June 5, 3,641 cases among ~3.5 mil fully vaccinated in MA–likely undercount due to lower testing in vaccinated. Yet CDC stopped counting unless hospitalized/dead🧵
nbcboston.com/news/local/mor…
2) According to the U.S. Centers for Disease Control and Prevention, a total of 10,262 breakthrough infections were reported throughout the country as of April 30, at which time 101 million people had been vaccinated.
3) More cases have likely gone unreported, federal officials have said, because they only have data from 46 states and territories. Additionally, most vaccinated people don't show symptoms that are serious enough to get tested.
Read 10 tweets
Eric Feigl-Ding Profile picture
16 Jun
Outbreak of 232 active #COVID19 cases in Ontario 🇨🇦 First Nation area of Kashechewan—majority are children under 12, those who aren’t yet eligible for vaccine, & kids <18 who are 1-dose vaccinated. A 12-year old is hospitalized too. ➡️Vaccinate kids ASAP.
theglobeandmail.com/canada/article…
2) Do kids get infected? Oh yes they do. Don’t listen to naysayers who say they don’t. And don’t listen to those who say kids don’t get sick. #LongCovidKids is real too.
3) let this sink in — 1% of all #COVID19 confirmed cases in kids lead to hospitalization.

Is that really an “acceptable” level of kids morbidity that we will allow in society?

?
Read 6 tweets
Eric Feigl-Ding Profile picture
16 Jun
DIFFERENT SYMPTOMS—‘Loss of smell’ is no longer a top 10 symptom of the new #DeltaVariant. A headache, sore throat & runny nose are now the most common. New study says catching Delta #COVID19 can feel different— "more like a bad cold" for younger people.🧵
bbc.com/news/health-57…
2) Since the start of May, we have been looking at the top symptoms in the app users - and they are not the same as they were," he says.
The change appears linked to the rise in the Delta variant, first identified in India and now accounting for 90% of Covid cases in the UK.
3) Fever remains quite common but loss of smell no longer appears in the top 10 symptoms, Prof Spector says.

"This variant seems to be working slightly differently," he says.
Read 11 tweets

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