[Thread] 1. Helen Rees (Sahpra board chair): SA can only approve #COVID jabs for use if they've applied with @SAHPRA1.
* SA has approved: #AstraZeneca, #JnJ, #Pfizer
* @SAHPRA1 is looking at applications from Sinovac and Sputnik
* No other jabs have applied for approval
2. Where is @SAHPRA1 at with Sputnik? Sahpra has requested more data - Sputnik hasn't submitted all the data that is required for a complete review of the safety and efficacy of the jab.
3. One of the issues with the Sputnik jab is that the type of adenovirus it uses is similar to one used an an HIV vaccine trial that was stopped early because there was data which suggested that it led to an increased risk of HIV infection among uncircumcised men.
4. Where is @SAHPRA1 with Sinovac? Sahpra has requested more data from Sinovac. In the past 48 hours, Sahpra received a WHO dossier with data the WHO used to approve Sinovac for emergency listing. Sahpra will now review that data.
5. No #COVID19 vaccines are 100% effective. None were developed to specifically be effective @ the Beta variant (rather against the original form of the SARS-CoV-2 virus). The Beta variant (the main form of the virus circulating in SA) alter the effectiveness of all jabs.
6. When SA looks at which vaccines to procure, it is important to select jabs that show efficacy against the Beta variant (because that's the dominant variant in SA). Although the Beta variant reduces the efficacy of all jabs, it reduces the efficacy of some more than others.
7. After Sahpra approves a #COVID jab, it monitors what's happening in the general population (with the help of the SAMRC). It, for instance, monitors for safety signals that emerges in large roll-outs among millions of people (vs. clinical trials conducted among smaller groups).
8. Because of the Beta variant, Sahpra needs as much data as possible that shows if a vaccine is effective against the variant (as the Beta variant is dominant in SA). It's developing a protocol to use to monitor the effectiveness of all vaccines when they're rolled-out in SA.

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More from @miamalan

19 Jun
[Thread] 1. LATEST details re the teacher/school staff #VaccineRollOutSA.

1. Which jab will be used? #JNJ
2. How many doses are needed? 1 per person
3. When will it start? Wed, 23 Jun
4. When will it end? Thurs, 8 Jul
5. How many school staff need to get vaccinated? 582 564 ImageImage
2. Who qualifies?

1. EVERYONE at gov schools
- 395 682 teachers
- 104 111 support staff
- 42 671 teachers/early childhood development staff

2. EDUCATORS working at (legally registered) private schools
- 42 671 teachers, but no support staff

3. Education dpt office staff ImageImage
3. Who else at government schools can get vaccinated?

1. Staff who transport children to and from schools
2. School feeding scheme staff
3. Staff who do remote learning programmes
4. Teacher union, security, cleaning staff Image
Read 8 tweets
18 Jun
[Thread] 1. Nicholas Crisp from @HealthZA: Since the start of #VaccineRolloutSA the lack of availability of jabs has constrained us. SA got 300 000 #JnJ jabs on Thu and will now (next week) start to vaccinate 582 000 school staff (public +private).

bit.ly/3gDp12K
2. School staff will be vaccinated within 10 working days. All provincial health/edu dpts will focus on vaccinating school staff during this period. 300 000 jabs are not enough, but we're getting more next week, also on a short exirry date (11 August).
3. The education departments will arrange transport for teachers and other school staff to special vaccination sites. They need to take their ID docs and also their medical aid cards, if they belong to one, to the sites.
Read 6 tweets
17 Jun
[Thread] 1. What do we know so far from @HealthZA about #CovidVaccinations for school staff:
1. 300 000 #JnJ jabs will be in SA by Fri (tomorrow)
2. Another batch from the US will arrive next week (nr of doses = not yet known)
3. Vaccinations will start on Wed, 23 Jun
2. Who qualifies?
1. All school staff (so not just teachers, cleaners, etc too) will be covered, regardless of age
2. Both public and private schools qualify
3. @healthza says between 550 000 and 580 000 staff need to be vaccinated.
3. When do the jabs expire?
@healthza says = 11 August (the FDA and Sahpra have approved an extension from 28 June to 11 August), but the aim is to try and vaccinate school staff within 10 days.
Read 4 tweets
15 Jun
1. [Thread] #CyrilRamaphosa on #VaccineRolloutSA: #JnJ will deliver 2 million jabs to SA by the end of June (so the 2 million doses we can’t use will all be replaced by the end of the month). Read our @Bhekisisa_MG story about this. bit.ly/3cFxdgo
2. #CyrilRamaphosa: Our first 300 000 #JnJ doses will be used to vaccinate teachers and school staff. Thereafter the next essential workers group that will be prioritised will be security personnel on the frontline. BUT: Our immediate task is to vaccinate people of 60+.
3. #CyrilRamaphosa : SA has the capacity to vaccinate 150 000 people/day (we’re currently doing 80 000 because of a lack of jabs - until our #JnJ jabs arrive).
Read 6 tweets
15 Jun
[Thread] 1. #CyrilRamaphosa: Restrictions are effective in bringing down #COVID infections. But although we have reason to hope, we still have a mountain to climb.
2. #CyrilRamaphosa: A third wave of infections are upon us. Since my last family meeting (2 weeks ago), the average nr of new infections has doubled from 3 700 daily infections to over 7500. Deaths have increased by 48% from 535 to 791 in the past 7 days.
3. #CyrilRamaphosa: Gauteng is particularly bad. The increase in #COVID infections in Gauteng is now worse than they were in previous waves at the same stage of the wave.
Read 8 tweets
13 Jun
[Thread] 1. BREAKING: Both President #CyrilRamaphosa and acting health minister Mamoloko Kubayi-Ngubane have confirmed that the FDA found SA's 2 million #JnJ jabs at Aspen in Gqeberha unsuitable for use. They can therefore not be released.
2. Mamoloko Kubayi-Ngubane (sent to me 17:45):
"I can confirm that 2 mil doses at Gqeberha have been affected + will not be used. Only 1 batch was regarded contaminated from USA + the other 1 was not but because they were stored together, it’s difficult to isolate one batch."
3. #CyrilRamaphosa at the G7 summit this afternoon: “I’m told they [Aspen] have to dispose of those they have already manufactured. They are going to start all over again with another batch.
bit.ly/3ghaCcf
Read 4 tweets

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