[Thread] 1. This graph shows how the Delta variant is spreading in SA (the green dots = the Delta variant). The yellow dots are the Beta variant, which has been dominating up until now. @Tuliodna says the Delta variant is likely to start dominating the global #COVID19 pandemic.
2. The Delta variant spreads faster than any other #COVID variant, including the Beta variant. It spreads 2x as fast as the original form of SARS-CoV-2 and 30-60-% faster than the Beta variant. It has been detected in 85 countries and causes 95% of infection in the UK.
3. The Delta variant is likely to dominate SA's #COVID19 pandemic. It presents a higher risk of reinfection, but there's no evidence that it reduces the efficacy of vaccines. The Delta variant is likely why we're seeing so many more infections in SA's 3rd wave vs. the 2nd wave.
4. The kind of symptoms that the Delta variant causes could be different to those of other variants. Mostly it is associated with headaches, a sore throat, runny nose and sneezing.
5. There is, however, no clear evidence that the Delta variant causes more severe disease. But because it spreads to much faster, it does result in more hospitalizations (because it causes more infections).
6. What effect does the Delta variant have on vaccines? Once you have had two doses of Pfizer or AstraZeneca, the jabs remain effective against the Delta variant. Pfizer provides more than 90% protection against hospitalization for #COVID caused by the Delta variant.
7. There isn't clear data yet, but it might be that people who have been infected with the Beta variant, can get reinfected with the Delta variant, says @rjlessells.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
🧵1. BREAKING: The peer-reviewed results of the study of a 6-monthly jab, #lenacapavir, in which not a single of the 2134 women between 16-25 years who received the jab contracted #HIV, were released at #Aids2024.
2. Women often find it hard to adhere to daily #oralPrEP. In the Purpose 1 trial, 91.5% of women returned on time for their next #lenacapavir jab at 26 weeks and 92.8% at week 52.
3. Only 4 women out of 2134 (0.2%) who received #lenacapavir dropped out of the trial because of injection-site reactions.
[Thread] 12 things to know about the the proportion of pregnant women infected with #HIV from SA’s latest antenatal HIV survey. The survey is conducted by the @nicd_sa.
(Analysis of our 95-95-95 goals in my next thread later in Jan).
1/12
2. What is the antenatal #HIV survey?
1. It measures the % of HIV+ pregnant women between the ages of 15 + 49. 2. Only women using state pregnancy clinics take part. 3. The survey has been conducted each year between 1990-2015, then in 2017, 2019 +2022.
3. How many pregnant women between 15-49’s blood was tested for #HIV? 37 828 out of 40 542 collected samples.
- 37 7171 = Black African women
- 37 541 didn’t live with the dad of their child
- 35,635 of dads were 5 years+ older than moms (this makes them more likely to get HIV)
JUST IN [Thread]:
1.@healthza's Lesley Broomberg:
An extra #COVID19 booster jab for people of 18+ in SA will become available towards the end of JANUARY
- People of 50+ qualify for a 5th dose
- People of 18+ qualify for a 4th dose
2. Lesley Broomberg: Can you mix and match with additional boosters? Yes. You can choose whether you want a #JnJ or #Pfizer booster.
3. Lesley Broomberg:
Will teens of 12-17 qualify for boosters? Not at this stage. Why not? The #VMAC = not recommended booster doses for 12-17, based on an understanding that the protection provided by 2 #Pfizer doses = adequate, as 12-17 = @ low risk of severe #COVID19 illness
[Thread] #JoePhaahla:
- Genomic surveillance Network reported the detection of the new subvariant XBB.1.5 in SA of a sample of a patient tested on 22 Dec
- Details of the patient = not known, it was a random sample taken for testing
- XBB.1.5 = also common in US
2. XBB.1.5 = common in US
#JoePhaahla:
- 97%+ of #COVID19 cases worldwide = still #Omicron
- XBB.1.5 cases = no major change in hospitalisations or deaths
- Immunity of SAs (vax and natural immunity) = still strong, so that is why we haven't seen much change in terms of hospital admissions/deaths
Which APIs will Aspen use?
India's Serum Institute's
2. Why is it NB that an African company makes these jabs?
#Africa imports almost all its jabs. #COVID19 showed us this results in Africa being last in line to get vaccines during pandemics. The grant to Aspen is 1 of the 1st steps to change that.
3. What's the goal?
By 2040, the African Union wants #Africa to make 60% of the jabs the continent uses.
Why?
So that Africa is better equipped 2 respond 2 outbreaks (by developing the ability to make jabs + have technology in place to also make new jabs during pandemics).
🧵1. BREAKING: @SAHPRA1 has confirmed the registration of the #HIV prevention jab, #CABLA in South Africa. On Thursday, #ViiVHealthcare issued their statement.
2. Who can use the jab? @SAHPRA1 didn't specify restrictions for use in their statement, only that it is "a highly effective option for people at substantial risk of #HIV infection."
3. How does the jab work? It uses an #ARV called cabotegravir that prevents #HIV from replicating and entering someone’s cells. It’s taken every two months. Read my latest story for more. bit.ly/3ER7ejq