📍”It’s clear all the signals are that there are groups that need booster shots in a couple of months” says @Bob_Wachter. I agree. The groups most likely are: immunocompromised, have major risk factors, the elderly, and those who had gotten shots earliest.
2) “it’s up in the air… what is clear is that if you got J&J as your first and only shot, you shouldn’t get another J&J, you should get either Pfizer or Moderna” says UCSF chair of medicine, @Bob_Wachter, on need for booster for J&J.
3) Why boosters? Couple reasons: #DeltaVariant is more evasive, vaccinations wane after 6 months, and elderly need more protection. See detailed thread 🧵 on these issues… ⬇️
4) Boosters—Biden WH Officials Now Expect Vulnerable Americans to Need Booster Shots—The growing consensus that at least some Americans will need a booster is tied in part to research suggesting that Pfizer’s vaccine is less effective after ~6 months nytimes.com/2021/07/23/us/…

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More from @DrEricDing

30 Jul
⚠️Holy Mother—the worst CDC #DeltaVariant report ever:

📌MORE CONTAGIOUS than Smallpox*

📌DOUBLE transmission of Wuhan 1.0*

📌MORE SEVERE than ever*

📌 Vaccinated can transmit* & breakthrough viral loads ~ unvaxxed.

➡️*Ever item I have warned before🧵
context-cdn.washingtonpost.com/notes/prod/def… Image
2) “The war has changed” is very similar to the ‘Pandemic 2.0’ language that I have been warning for months and months now with #DeltaVariant. This is not your old slow Wuhan 1.0 strain anymore.

washingtonpost.com/health/2021/07… Image
3) CDC internal report also reveals the results of an “CANARY IN A COAL MINE* unpublished Massachusetts contact tracing study revealing an outbreak of vaccinated to vaccinated transmission that was genomic sequencing confirmed. ➡️ why the hell is this not published yet?!?!?! Image
Read 12 tweets
29 Jul
📍1 in 5–Breakthrough & “Persistent Symptoms”: in fully vaccinated health care workers, lower neutralizing antibody titers ➡️ breakthrough #SARSCoV2 infections. Most were mild, but persistent symptoms occurred in ~1 in 5 (19%) breakthroughs for >6 weeks.
nejm.org/doi/full/10.10… Image
2) And this wasn’t even #DeltaVariant — this was the older winter #B117 #alphaVariant from the UK 🇬🇧— so we expect #DeltaVariant to be maybe worse given the viral load. Also viral load only slightly higher in the breakthroughs. Image
3) Dr Hyde is right that it could be an overestimate since they probably missed a lot of asymptomatic cases. But still, even among symptomatic breakthroughs- that’s a lot.
Read 4 tweets
29 Jul
🐘Smuggling elephant trophies & nonprofit corruption—LaPierres’ called for the elephants’ four front feet to be turned into “stools,” an “umbrella stand,” and a “trash can.” They deleted their names, shipped to a taxidermist, who trophied it for “free”. 🧵
newyorker.com/news/news-desk… Image
2) “Susan wrote back with a request: the shipment should have no clear links to the LaPierres. She told the shipping company to use the name of a taxidermist as “the consignee” for the items, and further requested that the company “not use our names anywhere if at all possible.”
3) “Susan noted that the couple also expected to receive, along with the elephant trophies, an assortment of skulls and skins from warthogs, impalas, a zebra, and a hyena.
Read 10 tweets
29 Jul
I now crown Alberta as the new ‘Florida of Canada 🇨🇦’ … get a positive #COVID19 test? ➡️ No need to isolate says new horrible rules by heinously irresponsible @CMOH_Alberta. ⚠️Meanwhile, COVID now spreading faster (RT=1.48) in Alberta than during peak of 3rd wave. #COVID19AB Image
2) “Health and infectious disease experts say the rate at which COVID-19 cases are growing in Alberta is alarming, as it spreads faster than during the height of the pandemic's third wave.”

google.com/amp/s/www.cbc.…
3) “The R-value, which represents the number of people infected by each infected person, was 1.48 (with a confidence interval of 1.38-1.59) in Alberta as of Sunday.
That number — which has doubled in recent weeks — means 100 people with the virus will spread it to 148 others.
Read 7 tweets
27 Jul
📈NEW RULES—@CDCDirector Walensky announces new mask guidance, regardless of #COVID19 vaccination, due to surging #DeltaVariant:

📌Wear masks indoors, in public areas with ‘high transmission’ (why not all?)

📌All K-12 schools wear a mask indoors. More—🧵
2) “some vaccinated people infected with the #DeltaVariant after vaccination may be contagious and spread the virus to others.”

We have known this for MONTHS. A little late but better than never.
3) @CDCDirector: “the big concern is that the next variant that might emerge, just a few mutations potentially away, could eventually evade our vaccine… for hospitalization & death.”

note: breakthrough mild infections allows transmission too. #Maskup
Read 10 tweets
27 Jul
📍75% of hospital #COVID19 admissions were unvaccinated, 9% were fully vaccinated without immune deficiencies, 5% were vaccinated with immune deficiencies, 11% `unknown', for all #DeltaVariant-surge hospitalizations last week, says Dutch govt report. 🧵 nos.nl/artikel/239113…
2) No differences were detected among vaccines for breakthroughs in terms of the risk of being hospitalized while fully vaccinated. Netherlands 🇳🇱 uses 4: AstraZeneca, Pfizer, J&J, and Moderna -. ➡️ We need CDC to report this for the US now!
3) we are seeing #DeltaVariant penetrating vaccines a lot, even Pfizer, among one of the best vaccines out there. It’s still good for #DeltaVariant hospitalizations— 88% efficacy, but this is lower than 93% last month and 98% in May. Must stay vigilant.
Read 5 tweets

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