2) “The war has changed” is very similar to the ‘Pandemic 2.0’ language that I have been warning for months and months now with #DeltaVariant. This is not your old slow Wuhan 1.0 strain anymore.
3) CDC internal report also reveals the results of an “CANARY IN A COAL MINE* unpublished Massachusetts contact tracing study revealing an outbreak of vaccinated to vaccinated transmission that was genomic sequencing confirmed. ➡️ why the hell is this not published yet?!?!?!
4) Worse, the internal CDC report declares in BOLD RED font that “Masking:
Given higher transmissibility and current vaccine coverage, ⚠️universal masking⚠️ is essential to reduce transmission of the #DeltaVariant”!!! UNIVERSAL MASKING—not just high risk areas. @CDCDirector?!?!
5) Am I exaggerating anything? No. My top post is essentially the same as the “Summary” conclusions on slide 22 of the CDC report. I am not exaggerating anything. And I am familiar with every single published study listed in this report. context-cdn.washingtonpost.com/notes/prod/def…
6) It cites a combination of recently obtained, still-unpublished data from outbreak investigations and outside studies showing that vaccinated individuals infected with delta may be able to transmit the virus as easily as those who are unvaccinated. washingtonpost.com/health/breakth…
7) Vaccinated people infected with delta have measurable viral loads similar to those who are unvaccinated and infected with the variant.
8) “I finished reading it significantly more concerned than when I began,” says @Bob_Wachter, chairman of the Department of Medicine at the University of California at San Francisco, wrote in an email.
9) “daunting task CDC faces—It must continue to emphasize efficacy of vaccines at preventing severe illness/death while acknowledging breakthrough infections may not be so rare after all, & that vaccinated individuals are transmitting—& move the goal posts in full public view.”
10) “Although it’s rare, we believe that at an individual level, vaccinated people may spread the virus, which is why we updated our recommendation,” according to the federal health official, who spoke on the condition of anonymity because not authorized to speak publicly.
11) “Waiting even days to publish the data could result in needless suffering and as public health professionals we cannot accept that.” ➡️ I complete agree.
12) why didn’t we know about breakthrough infections causing transmission earlier? Was the CDC lying or neglectful & derelict in their duty to monitor? ➡️Let’s rewind to May 2021–@CDCgov decided to ⚠️stop collecting & investigating⚠️ mild breakthroughs! 🔥 nytimes.com/2021/05/25/hea…
13) Also, the CDC is still also assuming basic cloth masks in this risk models — the CDC needs to start promoting PREMIUM MASKS ASAP!!! @kprather88@AbraarKaran@RanuDhillon and I have been pushing this for months to no avail! CDC rejected pushes for premium mask recommendations!
14) is the #DeltaVariant more severe of a strain? Yes. The CDC deck highlights 3 studies showing higher hospitalization risk and deaths. But it actually missed 2 other gigantic big studies that I’m aware of showing Delta more severe than Alpha🤦🏻♂️— c’mon @CDCgov - that is sloppy.
15) Sooooo, which 2 big #DeltaVariant studies did the @CDCgov miss? These two big ones from @PHE_uk and @P_H_S_Official … that found Delta to be 2.61x and 2.39x higher risk of hospitalization than Alpha #B117. What’s the date of the report? June 3rd 2021!!! That’s ~2 months ago!
16) Also we have long known vaccinated transmit. Singapore Delta outbreak proves that vaccinated still transmitted. In this #DeltaVariant cluster, among 29 vaccinated who got infected, 21 events were between vaccinated-to-vaccinated or unvaccinated—a lot! covid.viz.sg
17) and check out how the unvaccinated chain of transmission initially started from a vaccinated person!!! Even though most of transmission chain later was unvaccinated—it started from a vaccinated person who kick started the chain of cases. I warned about this before July 4th.
18) Oh cmon, when should @CDCgov have known? The data from Singapore Ministry of Health was all freely accessible online and updated **daily**… and you can see the above graph’s vaccine breakthrough #DeltaVariant cluster was already apparent by mid June!! covid.viz.sg
19) So how many breakthroughs were there in Singapore detailed contact tracing, including asymptomatic cases? ~125–or about ~30% of entire #DeltaVariant cluster. Almost 1/3 of cases were breakthroughs—and as shown above—dozens were transmitted from vaxxed. CDC was blind on this.
20) Oh gee, @CDCgov must have missed that 🇸🇬data—what about outbreak from a non-Asian country—Australian officials reported ~100% household transmission with #DeltaVariant. “even with vaccinated workforce there's still potential to transmit”. June 29th! 🔥 google.com/amp/s/www.bbc.…
21) Someone you know may have warned about vaccinated breakthrough cases still transmitting… July 2, 2021. When was the CDC internal memo acknowledging the same thing? July 29, 2021. 😞
22) but but but what about Israel and other highly vaccinated countries? Vaccines work well but their leaky transmission allows the virus to still circulate.
25) I’m worried about recent efficacy drop reports. Perhaps this Israel 🇮🇱 efficacy drop for #DeltaVariant might be on the high side but all studies finding it by now.
26) Bottomline is we need more NPI mitigation’s on top of masking. The @WHO was right— @doctorsoumya & her WHO team took the precautionary approach on #DeltaVariant declaring it a VOC in early May, and demanding masks in late June. CDC didn’t declare VOC for Delta until mid June.
27) Vaccinologist professor @PeterHotez thinks 3rd shot booster is now very likely based on where we are heading for Delta. I agree, as much as it sucks for developing countries who need vaccines urgently too — hence need faster WTO patient waiver and tech transfer.
28) 📍UPDATE—the CDC finally released that worrisome unpublished analysis from Massachusetts showing 74% of the mega outbreak being breakthroughs, and that among the breakthroughs— viral loads were similar in vaxxed and unvaxxed. This is why CDC ultimately had to reinstate masks.
30) I don’t quite know how to interpret this cartoon on @CDCgov anymore. @sacbee_news - HT.
31) @CDCDirector had this to say about transmission from an infected vaccinated person to someone else—she insists breakthrough infections are “rare”. But how do we really know? @CDCgov ordered not to track mild breakthroughs in May! We only have hospitalized breakthroughs data.
32) is it really rare? 74% of a mega outbreak on Cape Cod were fully vaccinated breakthrough infections. And Singapore outbreak had over 2 dozen breakthroughs that LED to transmission! In own cluster!
📺”Experts have been telling us that #COVIDisAirborne. Which means the dumbest thing you can do is bring healthy & infected people together breathing the *same air*” ➡️Best video all week! HT @thejuicemedia
2) This is also why “Florida of 🇨🇦” @CMOH_Alberta is so dangerously stupid and morally empty for allowing **INFECTED PEOPLE TO ROAM & MINGLE FREELY** even if they are known positive!!’
3) Every country has its own “morally empty” & “stupid” leaders. 🇨🇦 has 2—@DrBonnieHenry@CMOH_Alberta. ➡️Longtime mask-not-needed & airborne-denying Henry gloated that BC🇨🇦 had not seen #DeltaVariant "take off" when 7% of cases on June 5th—she then relaxed restrictions! Now? 61%
⚠️’CANARY IN COALMINE’ mega outbreak. Many large public events in Massachusetts town in early July led to 469 #COVID19 cases➡️ 74% in **fully vaccinated**; 90% sampled #DeltaVariant. *Viral loads similar* in fully vaccinated vs unvaccinated. CDC worried.🧵 cdc.gov/mmwr/volumes/7…
2) What are the implications for public health practice?
➡️ “expanded prevention strategies, including **universal masking** in indoor public settings, particularly for large public gatherings with travelers from many areas with differing levels of #SARSCoV2 transmission.”
3) People were jam packed on Cape Cod— “Persons with COVID-19 reported attending densely packed indoor and outdoor events at venues that included bars, restaurants, guest houses, and rental homes.” ➡️ 14 days later… local cases went from *zero* to 177 per 100,000 !! ⚠️
💡Problem with #DeltaVariant—while vaccine is good—“it is not a bulletproof vest against you (vaxxed) carrying the virus and you spreading it to others.” ➡️When did I warn folks? Filmed July 2, 2021. When did CDC internal memo leak? July 29th, 2021. 😞
2) Continuing on @60Mins— “Although they [Israel] are 60% fully vaccinated, guess what—the rest of the 40% that are not fully vaccinated are still spreading the virus… and it’s leaking through part of the vaccinated to those people as well.” ~July 2, 2021
3) here is the latest @CDCgov report… what a mess. So much drama and so many cases and so much suffering could have been prevented has we acted faster. And why the hell did it take a leaked CDC internal memo to warn the world?!?!
📍1 in 5–Breakthrough & “Persistent Symptoms”: in fully vaccinated health care workers, lower neutralizing antibody titers ➡️ breakthrough #SARSCoV2 infections. Most were mild, but persistent symptoms occurred in ~1 in 5 (19%) breakthroughs for >6 weeks. nejm.org/doi/full/10.10…
2) And this wasn’t even #DeltaVariant — this was the older winter #B117#alphaVariant from the UK 🇬🇧— so we expect #DeltaVariant to be maybe worse given the viral load. Also viral load only slightly higher in the breakthroughs.
3) Dr Hyde is right that it could be an overestimate since they probably missed a lot of asymptomatic cases. But still, even among symptomatic breakthroughs- that’s a lot.
🐘Smuggling elephant trophies & nonprofit corruption—LaPierres’ called for the elephants’ four front feet to be turned into “stools,” an “umbrella stand,” and a “trash can.” They deleted their names, shipped to a taxidermist, who trophied it for “free”. 🧵 newyorker.com/news/news-desk…
2) “Susan wrote back with a request: the shipment should have no clear links to the LaPierres. She told the shipping company to use the name of a taxidermist as “the consignee” for the items, and further requested that the company “not use our names anywhere if at all possible.”
3) “Susan noted that the couple also expected to receive, along with the elephant trophies, an assortment of skulls and skins from warthogs, impalas, a zebra, and a hyena.
I now crown Alberta as the new ‘Florida of Canada 🇨🇦’ … get a positive #COVID19 test? ➡️ No need to isolate says new horrible rules by heinously irresponsible @CMOH_Alberta. ⚠️Meanwhile, COVID now spreading faster (RT=1.48) in Alberta than during peak of 3rd wave. #COVID19AB
2) “Health and infectious disease experts say the rate at which COVID-19 cases are growing in Alberta is alarming, as it spreads faster than during the height of the pandemic's third wave.”
3) “The R-value, which represents the number of people infected by each infected person, was 1.48 (with a confidence interval of 1.38-1.59) in Alberta as of Sunday.
That number — which has doubled in recent weeks — means 100 people with the virus will spread it to 148 others.