Let's focus again on potentially preventable death from torso #hemorrhage.

Our paper in @ShockJournal highlighted the need to refocus our efforts on the prehospital setting (🧡here: )

But can we ID those patients successfully who might need ARC? 🧡
2/
We attempt to do so in this paper published in @JTraumAcuteSurg

Link here: journals.lww.com/jtrauma/Abstra…

Thanks to lead author @AhmerIrfanMBChB and coauthors at @uabmedicine for their hard work Image
3/
To recap: Advances of in-hospital care have been profound over the last >3 decades-those reaching alive & not in irreversible shock has a v reasonable survival chance.

A subset of patients (as high as 45% in some series) die in the field or w/i 1 hour of hospital arrival
4/
Death from high-grade torso bleeds occur w/i 30 min of point-of-injury (POI). There's an early peak w/i 1-2 hr for in-hospital death.

Holcomb showed time from POI to surgical hemorrhage control in some US trauma systems is a median 128 minutes...too late to help this group ImageImage
5/
Hence, our @ShockJournal paper pushed for considering (as the military as) specialist PH advanced resuscitative care (ARC) teams w/i trauma systems.

Critical for success is the ability to dispatch such a potential resource appropriately so it can arrive in time when needed Image
6/
The challenge with US #EMS is its decentralized & disparate nature-one area may be served by multiple call centers/agencies.
Training & experience of dispatchers can be limited. This places challenges on developing an ARC model in current US prehospital (PH) systems
7/
Our prospective observation/simulation study aimed to explore feasibility of early patient ID who might benefit from ARC in a typical US PH setting.

Two EMS agencies (serving about 100,000 people) & feeding into a single L1TC were chosen and evaluated over a 9 month period
8/
Both were asked to notify the L1TC/researchers (in real time) of actual patients who might benefit from the activation of a hypothetical trauma center-based ARC team (which could provide skills such as e.g. PH advanced airway/access/blood/#REBOA/thoracotomy) Image
9/
Agencies approached this task differently.

-Push notification of @Active911 scene/patient info to a senior paramedic, who would then decide on ARC team activation
-training the dispatcher on clinical scenarios (e.g. abd GSW w/ AMS) where the ARC team should be dispatched
10/
The study team would link PH and in-hospital data on these real patients. These were reviewed by experience investigators on appropriateness of the hypothetical ARC team activation & the potential benefit of that activation

PH times were calculated using geospatial data
11/
Results:
-63 calls
-peak times 4p-midnight
-70% call-outs w/i 2 min of 911 call
-33 patients taken to study L1TC (remainder presumed to have gone to another center - data missing)
-injury mechanisms/characteristics in table

Detailed PH data not available in 40 patients Image
12/
Of patients transported to L1TC
-5% intubated at scene
-10% intubated in ED
-2 patients arrested PH
-4 received chest tubes
-1 required thoracotomy
-38.3% required OR
-4 patients died (3 w/i 6 hours of POI)-all penetrating trauma patients
13/
Of our patient cohort, 10% were determined to possibly benefit from the hypothetical PH ARC team (table) to provide:
-surgical airway or difficult airway management
-thoracotomy
-transfusion
-chest decompression
-REBOA Image
14/
But would the team have arrived in time?
Data available for 31 patients
-median ARC ground travel time 22.9 min
-median air travel time 14.6 min

For the 6 who would benefit from ARC
-median predicted ground travel time 23.5 min
-median predicted air travel time 14.6 mins
15/
We showed partial success in testing of the organizational elements critical to ARC team success (appropriate patient ID & dispatch to allow timely arrival)

What did we learn?

When ID'd, majority (70%) ARC team call-outs occurred w/i 2 min of 911 call
16/
Although only 10% of our cohort would have benefited from ARC, likely this represents overtriage (inevitable as a system matures). This may be more refined with experience

We could not account for those just not ID'd by PH personnel or who may have died on scene
17/
Dispatcher training is crucial. To ID the patient who'd benefit from ARC team dispatch based on limited 911 call info under pressure requires experience.

Others have addressed this through having senior PH clinicians in dispatch centers, or even centralizing these centers Image
18/
Although our study had limitations, we do highlight
-the need to address potentially preventable PH hemorrhage
-consideration for ARC teams
-the need for organizational change/support to implement such change
-the challenges/barriers in current US #EMS set up
19/
I'll wrap it up by saying (again) that if we want to move the needle regarding potentially preventable mortality from torso/massive hemorrhage, we need to start taking steps to change/improve our current approach. Image

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More from @ResusOne

5 Oct 20
1/
Just out today (free) in @JAMASurgery
@Guyettef @Jjasonsperrymd @joshua_b_brown et al.
#TXA During Prehospital Transport in Patients at Risk for Hemorrhage After Injury: A Double-blind, Placebo-Controlled, Randomized Clinical Trial

jamanetwork.com/journals/jamas…

#staamptrial
2/
The role of #TXA has been the subject of varying debate.

This study asks if giving #TXA to #bleeding trauma patients in the #prehospital setting affects 30-day outcomes

This is a critical questions as #trauma remains a leading cause of death around the world

#StopTheBleed
3/
It is crucial we look at point-of-injury methods to control hemorrhage and hopefully affect outcome.

Remember, as this paper shows, there is a significant portion of patients in the prehospital setting that suffer potentially preventable death

pubmed.ncbi.nlm.nih.gov/25058244/
Read 18 tweets
6 Jul 20
1/
How does a city's trauma system come together to both prepare for the expected surge of the #COVIDー19 #pandemic & manage the ongoing #epidemic of #gunviolence & other trauma?

Through a great collaborative effort, we published the #Philadelphia experience in @JTraumAcuteSurg
2/

The full paper is published ahead of print here: journals.lww.com/jtrauma/Citati…

It represents the importance of #teamwork in ensuring a robust, rapid, coordinated effort to manage an evolving threat
3/

Our publication timing coincides with a brutal #July4th weekend where #Philadelphia saw over 30 people shot including several children

But how did the #pandemic and #socialdistancing mandate affect trauma volume in our centers?
Read 15 tweets
2 Jul 20
Important paper in @NEJM coming out of #Pakistan

RCT of amoxicillin for pneumonia in #Pakistan - the world’s largest community-based assessment of the use or withholding of antibiotics in children with mild pneumonia

Fantastic to see @FyezahJehan as 1st author

#welldone
2/
.@WHO recommendations for pneumonia recommend amoxicillin, but this conflicts with trial data showing possibility noninferiority of using amoxicillin.

Overuse of course leads to antibiotic resistance
3/
In this RCT
Kids 2-59 months (all from #Pakistan) who met @WHO criteria for nonsevere pneumonia with tachypnea
Assigned to either amoxicillin for 3 days or placebo

4002 children enrolled
Read 8 tweets
21 Dec 19
Recently our team had to manage a patient who presented critically unwell from post-tonsillectomy hemorrhage - something you may not see that often but can be a true life-threat!

(pictured is only one of several buckets)

My tips here:

1/x

#tweetorial
#foamed Image
Tip 1: Call for help early!

This patient did well because of excellent #teamwork from scene to OR. We received an alert from the EMS team, and informed ENT early (not in house) to the situation and need for OR. Anesthesia and OR team were also informed to prepare for this

2/x
Tip 2: Keep the patient sitting upright

Position is key. This patient was awake & alert, and keeping them upright allowed them to spit out the blood. Give them the suction to use also.

3/x
Read 9 tweets
22 Sep 19
Just released in @TSACO_AAST: Clinical use of #REBOA in civilian trauma systems in the USA: joint statement from @ACSTrauma @EmergencyDocs @NAEMSP @NAEMSP (utilizing best available evidence & expert consensus opinion)

Full text: tsaco.bmj.com/content/4/1/e0…

Key points (thread): 1/x
This document focuses on the use of REBOA
in civilian trauma patients & integration w/i
civilian trauma systems in the US. Emphasis
is on patient safety as the most important principle
while recognizing the variability in trauma systems, centers, and clinician training 2/x
The quality of clinical evidence to support REBOA use in trauma
patients is poor with no Class I or II data demonstrating that it improves outcomes or survival compared with standard
treatment.

Many studies also do not report patient outcomes beyond the
initial resuscitation 3/x
Read 15 tweets

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