2/ In late September 1918, Dr. Ernest Goodpasture admitted a patient to the hospital with what initially appeared to be a quote “typical attack of influenza.” He presented with a 3 day history of cough, dyspnea and fever to 103.0.
3/ He had no clinical evidence of pneumonia. His fever resolved and he was discharged home 3 days later. He felt ill after discharge, but returned to work. His cough persisted though, and weight loss and fatigue worsened.
3/ 3% of the general population >50 years old has MGUS and only a small percentage (1%) progress to malignancy such as myeloma or lymphoplasmacytic lymphoma. These patients are observed over time and no chemotherapy is given