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Hannah Davis 🌈 Profile picture
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28 Aug, 4 tweets, 2 min read
This age-adjusted data from Israel shows a deep decrease in vaccine effectiveness against symptomatic COVID infection for people who got vaccinated in January-February. #LongCovid

1/ Image
This was measured 2 months ago. Now that it's almost Sept, vaccine effectiveness for those vaccinated in April is likely close to the Feb numbers here.

And in the past few weeks, we've started seeing more breakthroughs from people who got vaccinated in April. #LongCOVID

2/
h/t @DanOfAmerica!
None of this should make people skeptical against vaccines. 6 months of protection against an *awful* virus with multisystemic effects is absolutely worth taking.

*And* it’s important to have knowledge like this to protect yourself. 3/

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More from @ahandvanish

Hannah Davis 🌈 Profile picture
31 Aug
Let's talk about...herpesviruses! And other reactivations in #LongCOVID.

When most people hear "herpesvirus" they think of STDs. But herpesviruses are a virus family, like coronaviruses.

Mono is a herpesvirus. So are shingles & chicken pox. All humans have at least one!

1/
Less familiar herpesviruses include: Cytomegalovirus (CMV, which ~50% of people have by age 40), Human-Herpesvirus-6 (HHV-6, which ~100% of people have), and Human-Herpesvirus-8 (HHV-8).

(Side note that this is all an explanation for laypeople, so I'll be simplifying a bit.)

2/
Herpesviruses are lifelong infections, but are usually latent, meaning they aren't "active". When the immune system is healthy, most people can keep them at bay. During times of illness/stress or in response to certain triggers (food, heat, hormones), these can flare up.

3/
Read 12 tweets
Hannah Davis 🌈 Profile picture
30 Aug
New CDC study finds that 36% of COVID patients *never seroconvert*, meaning they NEVER make antibodies! #LongCovid

This is a huge finding which we need to amplify broadly! Please retweet & send to providers, patients, support groups, #MedTwitter, etc.

wwwnc.cdc.gov/eid/article/27…
1/
They found two major risk factors that predicted a lack of seroconversion:

A) Age: people under 40 are statistically less likely to make antibodies. #LongCovid

2/
B) Small viral load: people who had higher PCR Ct values (meaning the test had to run more cycles before returning positive) were also less likely to seroconvert. This implies mild and asymptomatic cases are less likely to seroconvert. #LongCovid

3/ Image
Read 7 tweets
Hannah Davis 🌈 Profile picture
30 Jul
This seems to be the leaked data the CDC used to change the mask mandate this week:

context-cdn.washingtonpost.com/notes/prod/def…

There's a lot to dig in here but a few things that jump out about Delta particularly:

1/
Delta objectively spreads faster than the original COVID strain. The original strain was less transmissible than polio & smallpox; Delta is more transmissible than those as well as Ebola, MERS, SARS, & the Spanish Flu.

Delta is *as* transmissible as chicken pox.

2/
Delta is associated with a higher viral load and longer duration of shedding.

3/
Read 11 tweets
Hannah Davis 🌈 Profile picture
28 Jul
There are many ways to engage with #LongCOVID patients as a researcher without joining support groups, which compromises patients' privacy.

In addition to @patientled (associated with the @itsbodypolitic support group), here are a few options researchers may not know about.

1/
The COVID-19 Research Involvement Group has been around since spring 2020 and run by patient-researcher @Know_HG. It's associated with @long_covid support group and has over 2500 patients and researchers discussing Long COVID.

facebook.com/groups/2590602…

2/
The Medical & Scientific Collaboration group has been around since summer 2020 & is run by the renowned Long Haul COVID Fighters support group (@Amy_Ant, @katemeredithp). It also has about 2500 researchers & patients discussing avenues of research:

facebook.com/groups/3018438…

3/
Read 8 tweets
Hannah Davis 🌈 Profile picture
14 Jul
Happening now! I'll try to live tweet as I'm able.

Note: there are a few times where Q&As are welcome from the public! Questions can be pasted in the chat and will be answered during specific time slots. See the agenda for those times.

#LongCOVID

1/
First up Dr. Stanley Perlman on neurologic complications of coronaviruses generally (not just this one).

This study (from 20 years ago!!) shows that there is a discrepancy when the body tries to get rid of the virus, it causes inflammation/damage.

2/
-A specific coronavirus is theorized to be the initiator of multiple sclerosis (this is still at the theory stage)

3/
Read 59 tweets
Hannah Davis 🌈 Profile picture
25 Jun
Proud to have been a Subject Matter Expert to the POTUS Health Equity Task Force!

They're presenting today on what they learned about #LongCOVID (hhs.gov/live) & their presentation is so full of good recommendations that I can't even keep up.

1/
I'm thrilled at their takeaways, including 1) lab confirmation of COVID can't be required for care, 2) creating a federal advisory committee including LC patients, ME experts, & disability advocates, 3) help patients navigate the disability system & expediting claims, & others 2/
Excellent public comments from Michael Sieverts on how biases in PCR and antibody testing will trickle their way into research. Super important as research plans for #LongCOVID are currently being decided....

3/
Read 4 tweets

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