Thread by @miamalan

[Thread] 1. How many #COVID19 #vaccine doses has SA received and used since the start of #VaccineRollOutSA?

@HealthZA :
The total number of #JnJ and #Pfizer doses received by Nov 8 = 37,764,320

2. What's the breakdown — how many #JnJ and #Pfizer doses has #VaccineRolloutSA received?

@HealthZA :
JnJ: 10,695,200

Pfizer: 27,069,120
- Pfizer (bilateral agreement): 17,799,210
- Pfizer (COVAX): 1,392,300
- Pfizer (US donated doses via COVAX): 7,877,610

3. How many #COVID19 vaccine doses did #VaccineRolloutSA buy via bilateral agreements with #JnJ and #Pfizer?

@HealthZA :
#JnJ: 30,738,250 in Feb (we’ve received 10,695,200, so 34,8%)

#Pfizer: 30,002,310 in March (we’ve received 17,799,210 so 59,3%)

4. How many #VaccineRollOutSA #COVID19 jabs has SA used and have we got left?

By Nov 8 (acc to the @heatlhza dashboard) we had used:

#JnJ: 4,985,956 (so we have 5,709,244 jabs left)

#Pfizer: 17,668,828 (so we have 9,400,292 jabs left)

5. @HealthZA's dashboard says we have 5,709,244 #JnJ + 9,400,292 #Pfizer doses left. Is this accurate?

Not entirely. The actual nr of doses left = lower as the dashboard only reflects the jabs entered in the #EVDS. Some sites capture doses on paper + only enter them later.

6. How many #JnJ doses are we expecting 4 the rest of Nov?

#JnJ = not given delivery dates 4 the entire Nov:

11 Nov: 1,195,200
Week beginning 15 November: 3,931,200
TOTAL: 5,126,400

(If all doses arrive = 15,821,600 by wk of Nov 15, we'll have 51% of the doses we bought)

7. How many #Pfizer doses are we expecting for the rest of Nov?

#Pfizer has given @heatlhza delivery dates until Nov 22:

Nov 15: 2,311,920
Nov 22: 601,380
TOTAL: 2,913,300

(If all doses arrive on time, we would have received 20,712,510, so 69% of procured doses by Nov 22)

8. On Nov 8 #Sisonke2 started giving #HealthWorkers who received a 1st #JnJ dose, a 2nd booster #JnJ dose. Do those doses come from #VaccineRollOutSA’s stock?

No. #JnJ = donating 450,000 research doses needed for the study. The doses = used interchangeably with procured doses.

9. What % of #VaccineRollOutSA doses go 2 waste?

@heatlhza:
10%

Why?

1. Cold chain failure
2. Expired doses (exacerbated by decreased demand after doses had already been sent 2 sites)
3. Opening vials close 2 the end of a day + not enough people arrive to use all doses

10. Any other reason why 10% of #VaccineRollOutSA doses go to waste?

Yes.

Pfizer doses arrive in 6-dose vials. It’s complicated to extract the doses, so we often only manage to get 5 doses out of the vials.

11. Fewer people than expected are coming forward to get vaccinated (we’re currently doing fewer than 200,000 doses per day). Do any of our current doses run the risk of expiring before they get used?

No.

Why not? Let’s first look at how expiry dates work (next tweet).

12.
#Pfizer expiry dates = 9 mnths from the date of manufacture when they’re stored at -70 °C, but when moved to 2-8 °C the expiry is reduced to 31 days.

#JnJ expiry dates: Two years from date of manufacture when stored at -20 °C or 4,5 months (135 days) when stored at 2-8 °C.

13. There are doses that do expire when moved to warmer storage conditions. But all stock which is kept centrally is stored at the lowest possible temperature to i.e. -70 °C for #Pfizer and -20 °C #JnJ so they last as long as possible.

14. Also, to prevent #Pfizer doses from expiring (we’ve received far more #Pfizer than #JnJ), @healthza had fewer Pfizer doses delivered in Oct, so that supply better matches demand.

15. Why did some of the doses (part of the 10% wastage) expire then? Because demand decreased rapidly over the last 2 months, there were some doses that had already been delivered to sites that did expire, but supply is now being matched to demand to prevent the expiry of doses.

16. What’s the average expiry date of our current #Pfizer doses?

@HealthZA:
31 March/30 April 2022

But once moved from -70 °C this changes. When stored @ -20 °C they last for 14 days + a further 31 days @ 2-8 °C.

How long doses last depends on which temp sites store jabs @.

16. What’s the average expiry date of our current #JnJ doses?

@healthza:
Jun/Jul 2023

But to last until then, the jabs must be stored at -20 °C. When they're stored at 2-8 °C, they last for 4,5 months (135 days). So when they expire depends on which temp they're stored at.