Treating the underlying cause (vasodilation) with vasopressors would likely increase renal perfusion, urine output and help the kidney get rid of extra sodium (hypervolemic hypernatremia)
This actually happened! UOP, AKI and hypernatremia resolved with pressors!
/END
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👴 w Advanced Cirrhosis, hemorrhagic portal hypertension and hx of a heart block (w pacemaker).
Came to the ED w diarrhea 2/2 severe C. Diff.
Now in shock...
Initial resus with Norepinephrine 0.3 ug/kg/min, Crystalloid and albumin. Cr 3.8
1/7
18 hrs later, no renal improvement + oliguria.
MABP 70, CRT 2 seconds. 🧠 confused, + asterixis. No ascites or edema
Workup: hemodynamic AKI (⬆️SG, ⬇️UNa, ⬆️BUN/Cr, bland sediment)
Team wants to continue fluids, albumin and antibiotics... Dr. Harris, do you concur?
2/7
Obviously you are here for the #POCUS so here we go:
IVC: Plethoric (No subX window 2/2 intestinal air)
LV, RV: Relatively preserved systolic fx
Pacemaker lead seen causing important Tricuspid Regurgitation!
AKI Consult: 👵 ➡️ ED with severe DKA. CT Abdomen and Chest to look for infectious trigger: negative. Tx with IV insulin and balanced crystalloid + 6 L with obvious improvement. Cr was 2.7
Remained oliguric, now in sudden shock with increasing NE dose (0.5 ucg/kg/min) 🚨 1/12
#POCUS Very hyper-dynamic🫀 with increased contractility and no RV dysfunction.
🔎 Look carefully at color of flow exiting the LV:
Aliasing (green color): This means ultrasound system is trying to image an event that is occurring faster than the sample rate
2/12
This means flow is fast. But how fast? Choose the CW doppler setting and find out!
In this case acceleration was almost 6 m/s!
Flow acceleration occurs in the setting of obstruction (similar to putting your finger on the hose exit)
Pt w advanced liver cirrhosis. 🏥 Comes w worsening ascites. No fever🤒, no bleeding🩸. 🧠 ok, no asterixis. BP 91/50. Labs📈: AKI (Cr 3.0 mg/dl), UNa 7 mEq/L, bland sediment. #POCUS 👉small cirrhotic liver with significant ascites. Paracentesis ruled out PBE. 📊Poll below👇 1/11
What would your initial treatment be? 2/11
Don't treat reflexively. A thorough physical exam ♥️🩺revealed a systolic murmur at left lower sternal border. Neck exam 👇
📞 Nurse: Patient has a blood pressure of 226/118 mmHg!
📞 Resident: Nifedipine 30 mg STAT!
.....
📞 Me: About that last call, please hold Nifedipine until we assess the patient
A 🧵of some cases of Inpatient Hypertension 👇 1/15
🔎🖥️..This was a pt w ARDS on IMV. Other vitals 🆗. Previous BP= normal, no recent change in sedation, vent 🆗, no asynchronies. UOP = 0 for 2 hrs 🤔. Exam: Distended bladder!
After foley catheter change, BP normalised 😎
Why do we have this reflex to treat acute high BP? 2/15
A big component is the perceived expectation that we must do something! (In our minds, Are we trying to prevent organ injury?)