THREAD

1/

The other day, I tweeted about a recent study that adds to a growing body of evidence demonstrating the effectiveness of masks in preventing the spread of COVID-19...

2/

Here it is again--note that it's not a naturalistic or epidemiologic study, but a modeling study based on known information about the penetration of SARS-CoV-2 sized particles through N95/KN95 masks.

pnas.org/content/118/49…
3/

Now, my tweet only got 178 engagements, 22 likes, 18 retweets, and 2 replies to date, so it didn't make it very far in the Twitterverse.

But it did catch the attention of this one guy who responded: "lol. k"...

4/

...and retweeted this graph (w/ >1000 likes & 366 retweets to date) of COVID cases rising sharply in Nov in Germany, where they've had N95/K95 mask mandates in place for awhile, and used that to claim that their commitment to "science" had "failed."

5/

But let's take a closer look at this claim. First of all, no one claims that masks, or social distancing, or lockdowns, or even vaccines are magic armor reducing COVID risk to zero.

So, what we want to know is just how much such interventions reduce the risk, if at all.
6/

For Germany, we'd want to know how many COVID cases would've occurred had they not been "following science."

One rough way to estimate that is to look at COVID cases per capita in Germany compared its 7 neighboring border countries.

Suddenly, Germany's looking pretty good.
7/

And here's another study of the actual effects of mask mandates in Germany, published in Dec. 2020.

"Weighing various estimates, we conclude that 20 days after becoming mandatory, face masks have reduced the number of new infections by around 45%."

pnas.org/content/117/51…
8/

Meanwhile, in the US, here's @maolesen's comparison of COVID death rates in "red" vs. "blue" states.

The reason for this difference isn't clear, but it's likely due, at least in part, to partisan differences in mask wearing and vaccination rates.

9/

So yeah, #WearADamnMask. #GetVaccinatedNow. #GetBoostedNow. #trustscience.

And no, the rise of cases in Germany last month doesn't support the claim that following science is a fail.

im Gegenteil. or, in plainer English, "that's bullshit."
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More from @psychunseen

14 Oct
1/ THREAD

This story of COVID disinformation grift deserves much wider coverage.

Back in July 2020, #AmericasFrontlineDoctors stood on the SCOTUS steps and gave a press conference spreading misinformation about #COVID19

cnn.com/2020/07/28/tec…
2/ They claimed COVID was less deadly than the flu. WRONG!

They said masks don't help prevent COVID spread. NOPE!

They endorsed conspiracy that studies showing hydroxychloroquine was ineffective were "fake science" by "fake pharma companies." NOT TRUE!

rev.com/blog/transcrip…
3/

After Trump retweeted their video, it went viral and sparked a deluge of false claims on Twitter about #HydroxyChloroquine effectiveness for treating COVID19, with 84% of 2.7 million tweets about the drug over 9-day period containing misinformation.

thelancet.com/journals/landi…
Read 11 tweets
23 Mar
1/

Was just thinking there were few mass shootings during the pandemic.

Unfortunately, it looks like we're getting "back to normal" now.

This thread has some of my thoughts on mass shootings, #guns , & #GunReform through the years:

#Boulder #Atlanta

aeon.co/essays/does-a-…
2/

psychologytoday.com/us/blog/psych-…

"Guns make gun owners feel safer"
3/

"...while a few mass shooters in history have had serious mental illnesses, the more typical shooter has experienced the kind of milder difficulties with mood, anxiety, and social interactions with which most of us have some personal familiarity."

psychologytoday.com/us/blog/psych-…
Read 11 tweets
10 Mar
THREAD 1/

Do antipsychotics shrink the brain? No!

At long last, we have RCT data in 1st episode psychosis to disentangle effects of meds vs. disease.

nature.com/articles/s4138…
2/

Here are the striking findings.

At 3 months:

- no grey matter volume change in controls
- volume *loss* w/ placebo/psychosocial tx
- volume *increase* w/ meds
3/

The authors found no evidence to support confounding factors and therefore concluded that antipsychotic medications "prevent or perhaps even reverse" illness-related volume loss, consistent with a possible neuroprotective effect of 2nd generation medications.
Read 13 tweets
2 Mar
THREAD 1/

Harrow et al. have published another study demonstrating an association between antipsychotic treatment and poorer outcomes compared to non-antipsychotic treatment, this time for both schizophrenia and affective psychosis.
2/

To date, no RCT (no, not even Wunderink) exists to address potential causality or more precisely *direction* of causality. The million $$ question is whether antipsychotic discontinuation leads to recovery or whether recovery leads to discontinuation.

psychologytoday.com/us/blog/psych-…
3/

Harrow often uses baseline prognosis as a proxy of severity to address this question, but the only thing that really matters is *actual* disease severity. Why were meds stopped?

This is a chicken-egg issue as I discuss w/@awaisaftab here:

psychiatrictimes.com/view/there-bac…
Read 13 tweets
24 Feb
THREAD 1/

This article on "addiction as a brain disease" is a must-read update on an age-old debate.

IMO, much of it equally applies to "addiction" as other mental disorders.

(thanks to @zivacooper for sending).
2/

A few points worth discussing. First, addiction as disease is a counter-narrative in response to the:

"prevailing nonscientific, moralizing, and stigmatizing attitudes to addiction [that framed it as a] moral failing or weakness of character, rather than a 'real' disease.
3/

"This argument was particularly targeted to the public, policymakers and health care professionals, many of whom held that since addiction was a misery people brought on themselves, it fell beyond the scope of medicine..."
Read 21 tweets
14 Feb
THREAD 1/

Finally got around to reading and really enjoyed this new paper by @JasperFeyaerts et al. that offers a critical view of traditional conceptualizations of delusions and the (mis)assumption of a delusional continuum.

pubmed.ncbi.nlm.nih.gov/33485408/
2/

It affirms my view that firmly distinguishing between delusions and delusion-like (and shared) beliefs is ultimately doomed, because we do not have coherent existing definitions of "delusions" nor for that matter "beliefs"

Here are my favorite quotations from this paper:
3/

"Jaspers... points towards the experiential context within which primary delusions originate. Whereas delusion-like ideas arise in intelligible ways from everyday experience, primary delusions develop... as "a transformation in our total awareness of reality."
Read 10 tweets

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