[Thread] 1. SA's #Omicron#COVID19 wave seems to have turned (cautiously optimistic view). @rid1tweets: 1. Much steeper wave than previous waves, but also much shorter 2. Half the nr of days to reach the Omicron peak vs. peaks of other waves
2. The 7 day moving average of new #COVID19 cases for #Omicron (at what seems/could be the peak of the wave) = 23 4237 vs.
- #Delta peak 19,956
- Beta peak 19,042
- D614G peak 12,584
3. Here are the 7-day moving averages of new #COVID19SA cases, hospitalisations and in-hospital #COVID deaths up until 19 Dec (via @CAPRISAOfficial, @nicd_sa and DATCOV):
- Hospital admissions and deaths, at this stage, still significantly lower than in previous waves.
4. Test positivity rates (% of tests coming out +) until 19 Dec: 1. Mostly 30% + 2. Tu's 7 day-moving average (via @nicd_sa) = 30.1%
5. Provinces: LP, MP, FS, KZN = all show EARLY signs of their #Omicron waves turning.
- Data via @CAPRISAOfficial and @heatlhza)
6. WC, EC = early signs of turning; GP = confirmed to have turned. @hivepi, @nicd_sa:
- GP cases peaked on 9 Dec @ 97% of #Delta
- GP admissions peaked on 12 Dec @ 46% of Delta
- Deaths peaked @ 8% of Delta (still rising) bit.ly/3spGthq
7. Northern Cape = no signs of new #COVID19SA cases decreasing by 19 Dec.
8. @Dr_Groome, @nicd_sa:
Diffs between 3rd and 4th wave:
- In 3rd (#Delta) wave provinces started their waves at very different points in time
- In 4th (#Omicron) wave provinces = seeing their increase in cases and start of waves at a much closer point in time
9. Reasons behind fewer hospitalisations/deaths (so less severe disease, at this stage) could be: 1. Up to 70% of population in some provinces = previously infected (natural immunity) 2. Vaccination (44.5% of adults = 1 dose of vaccine) 3. Most hospitalisations = unvaccinated
10. #COVID19 vaccination coverage of adults (18+) in SA up until 19 Dec (via @CAPRISAOfficial and @HealthZA):
- 1 dose: 44%
- fully vaccinated: 39%
11. For the latest data on #Omicron hospitalisations, severity of cases, % of children admitted to hospital in SA, etc, @nicd_sa media briefing at 12 pm today. I'll be live tweeting.
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[Thread] 1. BREAKING: Treasury has awarded @healthza emergency funds of R753 528-mil via section 16 of the Public Finance Management Act to help fill the gap of the #Trump administration's cutting of #HIV and #TB grants.
2. R590 407-mil of the total of R753 528-mil will go to provinces for #HIV service delivery.
R32 121-mil will go to @healthza to support the CCMDD programme (this delivers chronic meds such as #ARin communities so people don't have to line up at clinics)
3. R132-mil of the total of R753 528-mil will go to the SA Medical Research Council to support medical research (lots of US grants were lost, especially from the NIH, although it looks like some of cuts may now be recversed by the NIH. science.org/content/articl…
🧵1. BREAKING: The peer-reviewed results of the study of a 6-monthly jab, #lenacapavir, in which not a single of the 2134 women between 16-25 years who received the jab contracted #HIV, were released at #Aids2024.
2. Women often find it hard to adhere to daily #oralPrEP. In the Purpose 1 trial, 91.5% of women returned on time for their next #lenacapavir jab at 26 weeks and 92.8% at week 52.
3. Only 4 women out of 2134 (0.2%) who received #lenacapavir dropped out of the trial because of injection-site reactions.
[Thread] 12 things to know about the the proportion of pregnant women infected with #HIV from SA’s latest antenatal HIV survey. The survey is conducted by the @nicd_sa.
(Analysis of our 95-95-95 goals in my next thread later in Jan).
1/12
2. What is the antenatal #HIV survey?
1. It measures the % of HIV+ pregnant women between the ages of 15 + 49. 2. Only women using state pregnancy clinics take part. 3. The survey has been conducted each year between 1990-2015, then in 2017, 2019 +2022.
3. How many pregnant women between 15-49’s blood was tested for #HIV? 37 828 out of 40 542 collected samples.
- 37 7171 = Black African women
- 37 541 didn’t live with the dad of their child
- 35,635 of dads were 5 years+ older than moms (this makes them more likely to get HIV)
JUST IN [Thread]:
1.@healthza's Lesley Broomberg:
An extra #COVID19 booster jab for people of 18+ in SA will become available towards the end of JANUARY
- People of 50+ qualify for a 5th dose
- People of 18+ qualify for a 4th dose
2. Lesley Broomberg: Can you mix and match with additional boosters? Yes. You can choose whether you want a #JnJ or #Pfizer booster.
3. Lesley Broomberg:
Will teens of 12-17 qualify for boosters? Not at this stage. Why not? The #VMAC = not recommended booster doses for 12-17, based on an understanding that the protection provided by 2 #Pfizer doses = adequate, as 12-17 = @ low risk of severe #COVID19 illness
[Thread] #JoePhaahla:
- Genomic surveillance Network reported the detection of the new subvariant XBB.1.5 in SA of a sample of a patient tested on 22 Dec
- Details of the patient = not known, it was a random sample taken for testing
- XBB.1.5 = also common in US
2. XBB.1.5 = common in US
#JoePhaahla:
- 97%+ of #COVID19 cases worldwide = still #Omicron
- XBB.1.5 cases = no major change in hospitalisations or deaths
- Immunity of SAs (vax and natural immunity) = still strong, so that is why we haven't seen much change in terms of hospital admissions/deaths
Which APIs will Aspen use?
India's Serum Institute's
2. Why is it NB that an African company makes these jabs?
#Africa imports almost all its jabs. #COVID19 showed us this results in Africa being last in line to get vaccines during pandemics. The grant to Aspen is 1 of the 1st steps to change that.
3. What's the goal?
By 2040, the African Union wants #Africa to make 60% of the jabs the continent uses.
Why?
So that Africa is better equipped 2 respond 2 outbreaks (by developing the ability to make jabs + have technology in place to also make new jabs during pandemics).