[Thread] 1. SA's #Omicron#COVID19 wave seems to have turned (cautiously optimistic view). @rid1tweets: 1. Much steeper wave than previous waves, but also much shorter 2. Half the nr of days to reach the Omicron peak vs. peaks of other waves
2. The 7 day moving average of new #COVID19 cases for #Omicron (at what seems/could be the peak of the wave) = 23 4237 vs.
- #Delta peak 19,956
- Beta peak 19,042
- D614G peak 12,584
3. Here are the 7-day moving averages of new #COVID19SA cases, hospitalisations and in-hospital #COVID deaths up until 19 Dec (via @CAPRISAOfficial, @nicd_sa and DATCOV):
- Hospital admissions and deaths, at this stage, still significantly lower than in previous waves.
4. Test positivity rates (% of tests coming out +) until 19 Dec: 1. Mostly 30% + 2. Tu's 7 day-moving average (via @nicd_sa) = 30.1%
5. Provinces: LP, MP, FS, KZN = all show EARLY signs of their #Omicron waves turning.
- Data via @CAPRISAOfficial and @heatlhza)
6. WC, EC = early signs of turning; GP = confirmed to have turned. @hivepi, @nicd_sa:
- GP cases peaked on 9 Dec @ 97% of #Delta
- GP admissions peaked on 12 Dec @ 46% of Delta
- Deaths peaked @ 8% of Delta (still rising) bit.ly/3spGthq
7. Northern Cape = no signs of new #COVID19SA cases decreasing by 19 Dec.
8. @Dr_Groome, @nicd_sa:
Diffs between 3rd and 4th wave:
- In 3rd (#Delta) wave provinces started their waves at very different points in time
- In 4th (#Omicron) wave provinces = seeing their increase in cases and start of waves at a much closer point in time
9. Reasons behind fewer hospitalisations/deaths (so less severe disease, at this stage) could be: 1. Up to 70% of population in some provinces = previously infected (natural immunity) 2. Vaccination (44.5% of adults = 1 dose of vaccine) 3. Most hospitalisations = unvaccinated
10. #COVID19 vaccination coverage of adults (18+) in SA up until 19 Dec (via @CAPRISAOfficial and @HealthZA):
- 1 dose: 44%
- fully vaccinated: 39%
11. For the latest data on #Omicron hospitalisations, severity of cases, % of children admitted to hospital in SA, etc, @nicd_sa media briefing at 12 pm today. I'll be live tweeting.
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🧵1. BREAKING: The peer-reviewed results of the study of a 6-monthly jab, #lenacapavir, in which not a single of the 2134 women between 16-25 years who received the jab contracted #HIV, were released at #Aids2024.
2. Women often find it hard to adhere to daily #oralPrEP. In the Purpose 1 trial, 91.5% of women returned on time for their next #lenacapavir jab at 26 weeks and 92.8% at week 52.
3. Only 4 women out of 2134 (0.2%) who received #lenacapavir dropped out of the trial because of injection-site reactions.
[Thread] 12 things to know about the the proportion of pregnant women infected with #HIV from SA’s latest antenatal HIV survey. The survey is conducted by the @nicd_sa.
(Analysis of our 95-95-95 goals in my next thread later in Jan).
1/12
2. What is the antenatal #HIV survey?
1. It measures the % of HIV+ pregnant women between the ages of 15 + 49. 2. Only women using state pregnancy clinics take part. 3. The survey has been conducted each year between 1990-2015, then in 2017, 2019 +2022.
3. How many pregnant women between 15-49’s blood was tested for #HIV? 37 828 out of 40 542 collected samples.
- 37 7171 = Black African women
- 37 541 didn’t live with the dad of their child
- 35,635 of dads were 5 years+ older than moms (this makes them more likely to get HIV)
JUST IN [Thread]:
1.@healthza's Lesley Broomberg:
An extra #COVID19 booster jab for people of 18+ in SA will become available towards the end of JANUARY
- People of 50+ qualify for a 5th dose
- People of 18+ qualify for a 4th dose
2. Lesley Broomberg: Can you mix and match with additional boosters? Yes. You can choose whether you want a #JnJ or #Pfizer booster.
3. Lesley Broomberg:
Will teens of 12-17 qualify for boosters? Not at this stage. Why not? The #VMAC = not recommended booster doses for 12-17, based on an understanding that the protection provided by 2 #Pfizer doses = adequate, as 12-17 = @ low risk of severe #COVID19 illness
[Thread] #JoePhaahla:
- Genomic surveillance Network reported the detection of the new subvariant XBB.1.5 in SA of a sample of a patient tested on 22 Dec
- Details of the patient = not known, it was a random sample taken for testing
- XBB.1.5 = also common in US
2. XBB.1.5 = common in US
#JoePhaahla:
- 97%+ of #COVID19 cases worldwide = still #Omicron
- XBB.1.5 cases = no major change in hospitalisations or deaths
- Immunity of SAs (vax and natural immunity) = still strong, so that is why we haven't seen much change in terms of hospital admissions/deaths
Which APIs will Aspen use?
India's Serum Institute's
2. Why is it NB that an African company makes these jabs?
#Africa imports almost all its jabs. #COVID19 showed us this results in Africa being last in line to get vaccines during pandemics. The grant to Aspen is 1 of the 1st steps to change that.
3. What's the goal?
By 2040, the African Union wants #Africa to make 60% of the jabs the continent uses.
Why?
So that Africa is better equipped 2 respond 2 outbreaks (by developing the ability to make jabs + have technology in place to also make new jabs during pandemics).
🧵1. BREAKING: @SAHPRA1 has confirmed the registration of the #HIV prevention jab, #CABLA in South Africa. On Thursday, #ViiVHealthcare issued their statement.
2. Who can use the jab? @SAHPRA1 didn't specify restrictions for use in their statement, only that it is "a highly effective option for people at substantial risk of #HIV infection."
3. How does the jab work? It uses an #ARV called cabotegravir that prevents #HIV from replicating and entering someone’s cells. It’s taken every two months. Read my latest story for more. bit.ly/3ER7ejq