Can't Find a C19 test?
Low supply, Fiat Demand...

I am shocked at how expensive these C19 tests are ($100-$300).

And no...The free ones are not free!

They are printing money, diluting yours and paying a heavy price you just can't see.

Diagnostic PCR is usually $30.
Even with 10X higher margins on C19 PCR, there are still droughts after 2 years?

Why?

This is the story of central planning where the market gets run by whimsical gov diktat and pricing signals are destroyed.

When pricing signals are destroyed companies dont know how to plan
Will Biden have an aneurism or an epiphany today and order 500M tests they fumble?

Will schools panic on Omicron and order more school testing of asympto kids who don't get sick?

When you run the market by Fiat, you create artificial demand but you don't create supply.
Supply is forecasted with pricing signals.
If you can't get a C19 test that is marked up 10X from traditional PCR costs.... good luck getting a cancer PCR test that is competing for the same nucleotides and polymerases.

These deaths wont be televised
Central planning always leads to starvation.

Today, we get to see how the central planners starve society of polymerases and nucleotides by destroying price signals.
But this topic is a century old and power hungry people always try to bury it
mises.org/library/econom…

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More from @Kevin_McKernan

29 Dec
I’m in the process of updating this for submission (2,000 downloads before submission)
Several details people have brought up in support of this.

Will walk through them.

osf.io/bcsa6/
1)Some folks at NIH reached out pointed out the work on ribosomal pausing that we missed.
It’s very relevant.

Just the codon change in the FCS is enough to pause the ribosomes and alter 3D structure of spike.
Just 2 codons!

mdpi.com/1422-0067/22/1…
They changed many codons.

2)pseudouridine and N1-methyl should be better spelled out. Xia et al conflates the two and we will spell this out more.
PseudoU wobbles more the methylpseudoU but both significantly alter Tm and thus are ‘stickier’ bases than disrupt translation.
Read 11 tweets
22 Dec
230 days RNA positive post infection.

Turn off the asymptomatic PCR pipeline or we’ll never get out of this.
Tissue specific viral heteroplasmy.
That’s wild.
Very thorough.
Not only applied a live-dead like PCR looking at sgRNA, they also cultured the virus and looked for immune histochemistry confirmation of proteins.
Read 8 tweets
22 Dec
Great chat with @jjcouey
I have some errors to confess to as I spoke to fast.
1)I was enrolled in a PhD program at UW but dropped out to focus on my job when the HGP starting racing with Craig Venter. So No PhD.

twitch.tv/videos/1239989…
2)nsp13 should be nsp3. It interacts with quadruplex G
academic.oup.com/nar/article/49…
3)The vaccines have N1-Methyl Pseudouridine and I shouldn't shorthand this to Pseudouridine as the former has less wobble than the latter. N1-Methyl does alter the Tm and increase base stacking in RNA but its methyl group steals one potential H-bond.

ncbi.nlm.nih.gov/labs/pmc/artic…
Read 9 tweets
16 Dec
Here we can see honest virologists being confronted by ones that might have been named in Fauci’s email.

The later amplify flawed preprints from Drosten.

The reads are not out yet (of course), so there is not much to say about this headline whore print.
Let’s have a look at the methods section of the paper.

2 rounds of 45 cycles of PCR?

This is what you do if you want to make polymerase slippage errors near GC rich triplet repeats.

People this library illiterate shouldn’t have the keys to $20K NovaSeq runs.
Having engineered very accurate sequencers, to address PCR polymerase error, you must utilize DNA barcodes that get attached to your PCR products in the first cycle of PCR. Any barcode that over amplifies through the PCR process is discounted.

For rare variants
This is the way
Read 6 tweets
14 Dec
The first author of this paper is the patient.

Raw deal. Vax may have accelerated oncogenesis? And he still has cordial things to say about the vaccines risk/reward.

It’s a preprint

frontiersin.org/files/Articles…
We touch on some of hypothetical pathways for this in this paper with the now Joe Rogan Pal Peter McCullough.

osf.io/bcsa6/
Link to the paper that has that image here.

frontiersin.org/articles/10.33…
Read 7 tweets
11 Dec
Of the many mutations in omicron the most interesting two are in the SEB domain.

Staphylococcus Enterotoxin B is a peptide that is classified as a bioweapon.

When ingested it creates symptoms very similar to COVID and it’s know to trigger cytokine storms Image
It’s well described in Cheng et al.

This known toxin was warp sped into spike only Vaccines.
SEB is directly adjacent to the FCS.

Let’s have a look at what Ahanotu et al has to say about SEB exposure and it’s capacity as a bioweapon.

pnas.org/content/117/41… Image
Exposure to these peptides has been known to cause cytokine storms.
They are superantigens.

liebertpub.com/doi/pdfplus/10… Image
Read 14 tweets

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