Michael Head Profile picture
May 17 12 tweets 5 min read
The UK #monkeypox outbreak is very interesting. A 🧵of some key points
- typically very limited human-to-human transmission, needs very close contact
- therefore, transmission is nothing like #COVID19
- to add to other #publichealth voices, very very low risks to wider general public
- if close contact, then public health teams will follow up
- monkeypox can be very nasty (case fatality rates upwards of 1%, albeit most outbreaks in areas where healthcare is v limited)
- UK has several specialist facilities for handling unusual tropical medicine cases. NHS is very good at this.
- Name is a bit misleading. First identified in monkeys, but small animals like rats/other rodents a more common host (typically in parts of West/Central Africa)
- interesting hypotheses that less #smallpox vaccination means lower population immunity against the related-but-different monkeypox virus, and thus outbreaks may become more common.
- that's very much tbc, but is plausible and interesting
- imported cases do indicate a wider burden of disease elsewhere in the world.
- we should be giving more consideration to understanding local and global implications of #LassaFever, #monkeypoxvirus, #Ebola and other rare but serious pathogens.
(/end)
To add, and follow up on another thread (with useful context) & this point around sexual contact

No evidence that #monkeypox is a sexually-transmitted infection. But, prolonged close contact required for intimacy or sexual activity may allow transmission
We do see similar with other infections, for example scabies (cc @jackiecassell) .
That is a skin infection transmitted by mites. The clinical presentation is sometimes in the groin, & the disease itself can be transmitted via the close contact of sexual or intimate activity.
Here, with #MonkeypoxVirus , implications around potential sexual contact between cases are not so significant, in that we know close contact is required for transmission, and therefore that is possibly what happened here
However, the social dynamics around transmission of infectious diseases means this may be useful consideration for the #publichealth teams involved in the contact tracing process. (/end_of_thread_for_now)
Well now independent.co.uk/news/health/mo…
#monkeypox confirmed in Portugal and possibly Spain. Suggestion is sexual networks, and "characteristics of the eight suspected [Spain] cases point towards fluid contact"
So not respiratory transmission, if so.
More to come on this story, then. Biggest European outbreak of monkeypox.
Contact tracing and outbreak investigation crucial, in understanding if any links between the countries, or multiple importations with subsequent community transmission etc...

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More from @michaelghead

Nov 1, 2021
Quick summation of thoughts around JCVI. Broadly agree with the concerns 👇, but have other comments

I also agree with views that 12-15 years vaccination should have been implemented a lot earlier. So much evidence in favour, never been much against.
(1/n)
I think a lot of the concerns could have been resolved by clearer comms.
Though bear in mind the top-level comms comes from Dept of Health & Social Care. Including decisions around publishing minutes, and what to publish/redact.
Consensus statements trump individual comments, that could have happened here with JCVI.
Where individual comments are ambiguous (for whatever reason) that can (and has here) muddied the waters.
Among the things that could be made clearer…
Read 20 tweets
Oct 23, 2020
SAGE have now put out a statement, highlighting that segmentation (trying to reach #herdimmunity by letting the virus rip through a population) is not a good idea.

assets.publishing.service.gov.uk/government/upl…
(1/n)
This follows on from many other expert groups saying the same. And there has been suggestions that scientists are divided on this topic.
Individually and collectively, they/we're really not... here's a few more examples...
The WHO, who called the idea ‘scientifically problematic and unethical’.
who.int/news-room/q-a-…
Read 14 tweets
Aug 29, 2020
Pleased to announce new #beatNTDs paper published, covering our 2019 study on #scabies and skin infections in #Ghana.
Published in Transactions @RSTMH, with equity in authorship - academic.oup.com/trstmh/advance…

#globalhealth (/1)
We trained healthcare staff on recognising scabies & other skin infections. Over 6-month period, study clinics recorded and reviewed 385 cases of skin infections. There were 45 diagnosed scabies cases (3rd most common skin infection, behind bacterial #dermatitis and #tinea) (/2)
We also assessed how far the patient travelled from home to clinic. There was a lot of ‘bypassing’ (i.e. they did not attend their nearest health centre, they travelled further than in theory they needed to) (/3)
Read 11 tweets

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