Discover and read the best of Twitter Threads about #smallpox

Most recents (24)

Fernando Simón en @ranm_es #monkeypox: "lo más probable es que este brote no se extenga mucho más allá en el tiempo". "Un infectólogo podría haber diagnosticado una lesión individual en la mano de un paciente" #siespecialidadEEII @SEIMC_
"Esto no ha pasado por casualidad, vivimos en un mundo cada vez más pequeñito" #OneHealth
Paz Sánchez Seco:"la prueba diagnóstica se desarrolló originalmente para diagnóstico de viruela en el contexto de un ataque #CBRN"
Read 9 tweets
Multi-country #monkeypox #outbreak: situation update

780 laboratory confirmed cases of monkeypox have been reported to or identified by #WHO from 27 Member States across four WHO regions that are not endemic for monkeypox virus.
#Monkeypox outbreaks in endemic countries in the #African región, 2022.

1408 suspected and 44 confirmed cases including 66 deaths were reported from seven endemic countries
WHO #Risk assessment: MODERATE considering this is the first time that many #monkeypox cases and clusters are reported concurrently in non-endemic and endemic countries in widely disparate WHO geographical areas.
Read 9 tweets
Was muss ich über #Affenpocken wissen?

1. Was sind Affenpocken❓

Affenpocken sind eine seltene, vermutlich vor allem von Nagetieren auf den Menschen übertragene Viruserkrankung. Übertragungen von Mensch-zu-Mensch sind selten, aber möglich, vor allem bei engem Kontakt.
#Affenpocken werden ausgelöst durch das Affenpockenvirus Orthopoxvirus simiae (auch #Monkeypox virus, #MPXV) aus der Gattung Orthopoxvirus. Das Virus ist verwandt mit den klassischen humanen Pockenviren (Variola, #Smallpox)
#Affenpocken beim Menschen wurden erstmals 1970 in der Demokratischen Republik Kongo bei einem 9 Monate alten Jungen identifiziert.
Im Frühjahr 2003 kam es zum ersten Nachweis von Affenpocken außerhalb des afrikanischen Kontinents.
Read 13 tweets
Why I feel we will have a much bigger outbreak of #MonkeyPox & top 70 updates ( we had 50 yesterday ) in the thread below . Let's start by what we already know & then go further

51/n Spain is seriously looking at whether the 80K strong LGBT community get together was a super spreader , they are also trying to find if one of the Saunas ( where gay men go for sex) has been the source , so the consequences are not due to genital spread but congregation ctd)
52/n The problem is its large number of likely reservoirs and things we probably can't entirely avoid including animal droppings : rats, mice, squirrels, shrews, opossums, ground hogs etc . So once it gets into a geographical location #monkeypox will be a tough nut ctd)
Read 21 tweets
#ฝีดาษลิง #monkeypox จริงๆเป็นคำเรียกที่ผิด (misnomer) นะครับ แต่เรื่องจาดเจอครั้งแรกในลิงเลยอนุโลม เอาเข้าจริงเราเจอมากในสัตว์ฟันแทะ (เช่น หนู) เมื่อเกือบ 20 ปีที่แล้ว มีการระบาดของฝีดาษลิง 47 คนที่อเมริกาเนื่องจากนำหนูแพรรี (prairie dog -รูป) จากประเทศกาน่ามาเลี้ยง ครั้งแรก 1/ Image
ที่เรารู้จักฝีดาษลิงย้อนไปหลายสิบปี 1958 แต่มาพบในคนเมื่อ 1970 ที่คองโก โรคนี้มีไข้ ตุ่มหนอง และต่อมน้ำเหลืองโต ถ้าไม่มีอาการแทรกซ้อนก็สามารถหายได้เอง ในอดีตเมื่อมีผู้เสียชีวิตจากฝีดาษลิง แต่นั่นต้องคิดว่าเป็นหลายสิบปีที่แล้วซึ่งการแพทย์ยังไม่พัฒนามาก หลังจากการระบาด 2/
ครั้งแรกที่ดูเหมือนมีคนเสียชีวิตมากหน่อย ก็มีการระบาดประปรายในแอฟริกา แต่มีคนตายลดลง แต่ระบาดนอกแอฟริกาครั้งแรกที่อเมริกา 47 เคสดังที่ผมเล่าให้ฟังข้างบนไม่มีผู้ใดเสียชีวิต (มีผู้ป่วยป่วยเด็กที่มีอาการหนัก 2 รายแต่รอดชีวิต) ผู้ติดเชื้อเกือบทั้งหมดสัมผัสหนูแพรรี่ หรือที่อยู่มัน 3/
Read 9 tweets
As far as The Third Strain of #MonkeyPox, the cure can be found within Planet Of The Apes #OR CONGO …

If you should happen to come down with #SmallPox Strain Number 3, Find ‘Tarzan’ & ask him for help …
Tarzan is the only one who can/is allowed to Swing from Branch to Branch
Within the Biblical Bloodline Tree of life …
Tarzan keeps the peace with ALL Biblical Bloodline Families on EVERY branch, including the TRUNK of the Tree …
Tarzan = Pure

Read 5 tweets
Mousepox, caused by orthopoxvirus ectromelia virus, closely related to #smallpox only infects mice. In mice it causes a mild illness. In 2001 Australian scientists were developing a contraceptive vaccine for mice. But it killed all the mice. (Thread)…
The vaccine was to help control mouse breeding and reduce agricultural damage . They used ectromelia virus as a vector to carry mouse egg proteins so the mice would develop antibodies to their own eggs and thereby become infertile.
They inserted a gene for production of interleukin-4, a cytokine that stimulates the immune system, hoping this would accelerate the production of antibodies. When they vaccinated the mice with smallpox vaccine (which also protects against ectromelia virus),
Read 6 tweets
Monkeypox is an Orthopoxvirus like Small Pox or Vaccinia virus. They are brick shaped linear dsDNA viruses that replicate in cytoplasm. They bind to glycosaminoglycans to enter cells or are taken up by apoptotic mimicry #monkeypox #orthopoxvirus 1/n…
Small Pox is the archetypal orthopoxvirus infection of humans which infected humans from prehistory until its eradication in the 20th century through Vaccination. First true success of Vaccines 2/n #Variola #SmallPox #orthopoxvirus…
History of Small Pox Vaccination is the history of Vaccination itself. Life long immunity produced against Small Pox, which could be mimicked by attenuated cowpox (Vaccinia) was the key to Small Pox eradication 3/n #Vaccinia #SmallPox #orthopoxvirus…
Read 37 tweets
MPX is an orthopoxvirus closely related to #smallpox. It has 2 clades- the milder one has a fatality rate similar to #SARSCoV2 - the other, closer to SARS1 at 10%. UK outbreak caused by the milder clade. #monkeypox has surged since 2017 due to (thread)…
A combination of waning immunity from smallpox vaccines - mass vaccination stopped by 1980, when SPX declared eradicated; population growth and ecological factors as we explored…
Smallpox vaccines work against MPX, and also work as post-exposure prophylaxis in a strategy devised during the eradication campaign called "ring vaccination" because of a long incubation period.…
Read 7 tweets
LIVE: Media briefing on #COVID19 and other global health issues with @DrTedros…
"Over the last week, #COVID19 cases have risen in four out of the six WHO regions. Due to testing and sequencing reducing in many countries, it is increasingly difficult to know where the virus is and how it’s mutating"-@DrTedros
"The Democratic People’s Republic of Korea has announced, through their state media, their first outbreak of #COVID19, with more than 1.4 million suspected cases since late April"-@DrTedros
Read 31 tweets
The UK #monkeypox outbreak is very interesting. A 🧵of some key points
- typically very limited human-to-human transmission, needs very close contact
- therefore, transmission is nothing like #COVID19
- to add to other #publichealth voices, very very low risks to wider general public
- if close contact, then public health teams will follow up
- monkeypox can be very nasty (case fatality rates upwards of 1%, albeit most outbreaks in areas where healthcare is v limited)
- UK has several specialist facilities for handling unusual tropical medicine cases. NHS is very good at this.
- Name is a bit misleading. First identified in monkeys, but small animals like rats/other rodents a more common host (typically in parts of West/Central Africa)
Read 12 tweets
It’s #WorldImmunizationWeek!

If you could see viruses you would know that they are all around. Vaccines provide opportunity and hope for all of us to enjoy ​a more fulfilling life. ​That's something we should all be fighting for.​ Vaccines, in the pursuit of a #LongLifeForAll.
This #WorldImmunizationWeek, let's celebrate life’s relatable moments that make us happy to be alive.
Dinner with friends.
A first kiss.
A first dance.
An early start to the day.
A family reunited.

#LongLifeForAll Image
Ever since the 1st vaccine was developed for #smallpox in 1796, the 🌍 has seen their unparalleled impact on health and wellbeing. People have been vaccinated for centuries, leading to the eradication of smallpox and driving down polio cases to an all-time low. #LongLifeForAll Image
Read 9 tweets
Daily Bookmarks to GAVNet 12/09/2021…
Merck's COVID-19 pill significantly less effective in new analysis…

#COVID19 #pill #effectiveness
The superfoods that fueled ancient Andeans through 2,500 years of turmoil…

#IndigenousDiets #superfoods #agriculture #EnvironmentalImpact
Read 13 tweets
Daily Bookmarks to GAVNet 11/28/2021…
Smallpox vials found at Montgomery County lab, but ‘there is no basis for being worried’…

#smallpox #laboratories #InfectionRisk
Satellites offer new ways to study ecosystems—and maybe even save them…

#RemoteSensing #SatelliteTechnology #EcosystemsHealth #CorrectiveAction
Read 13 tweets
just about 1 year after the 2001 anthrax attacks
#Newsweek magazine runs a cover:

Operation Smallpox, Inside the Emergency Plan to Innoculate Every American

check out the entire scanned article in this thread (cont) Image
October 2002 #Newsweek article about #smallpox bioterrorism and the plan to vaccinate every American in the event of a smallpox virus attack

(cont) Image
'The Team' designated to head this smallpox bioterrorism prevention plan included NIAID head Dr. Anthony Fauci, Jerome Hauer (Kroll, SAIC) & HHS head Tommy Thompson

(cont) ImageImage
Read 7 tweets
Eugene Debs - Secret Agent Man
We get most of the standard red flags on #Debs, including coming from a family of old wealth. It is admitted his father came from a wealthy French family. It looks like Debs may also have been Jewish.
The Socialist Party was led in those decades by five men: Morris #Hillquit (who was really Morris Hillkowitz), Victor #Berger, Daniel #deLeon, Eduard #Bernstein and Eugene #Debs. The first four are admitted to be Jewish.
Debs' grandmother on his father's side was Catherine Marguerite Hoffman. Her parents have been scrubbed, but the surname is Jewish. Debs' mother was Marguerite Marie Betterich and her genealogy has also been scrubbed. We do not know who her parents were.
Read 151 tweets
There’s been a lot of discussion recently about #SARSCoV2 #vaccine effectiveness, hospitalisation, and the reason for increasing case numbers, in spite of our high rates of vaccination. This thread will not provide a definitive explanation for the above 1/n
However, I’m hopeful it will provide context to inform the discussion. TL:DR The vaccines are not 100% effective so our current level of uptake – measured across the entire population – will not be sufficient, in isolation, to suppress #SARSCoV2 transmission in the community 2/n
Over the last 18 months, the concept of “herd immunity” has been frequently referenced in public discourse: I prefer, and will use, the term “community level protection (CLP)”, thereby illustrating the concept that immunising the community is capable of 3/n
Read 18 tweets
#Vaccines appreciation post courtesy of
#ChathamCounty public health department. Each of these is a reminder of the miracle of vaccination and the millions of lives saved.
1) #Polio - wild Polio was eliminated in Africa last year. Global #Eradication is the goal.
2) #Smallpox - #eradicated through vaccination since 1980
3) #Varicella #Chickenpox - effective vaccines have reduced hospitalization from this childhood disease by the thousands.
Read 8 tweets
"Finding the #smallpox to be spreading much and fearing that no precaution can prevent it from running through the whole of our Army...", General #GeorgeWashington instituted the first mandatory widespread #inoculation order in #militaryhistory on Feb 6 1777. #COVID19 #vaccines
2. GW recognized the risks especially that inoculation, unlike vaccines, led to the contraction of a "less" virulent case. "This Expedient may be attended with some inconveniences and some disadvantages, but yet I trust in its consequences will have the most happy effects."
3. But for GW it was a military necessity and an order that was needed to be given to save the army, the Revolution, and the nation.
Read 22 tweets

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