Discover and read the best of Twitter Threads about #smallpox

Most recents (24)

LIVE: Opening of the 76th World Health Assembly with @DrTedros. #WHA76…
@DrTedros "In 1977, Ali Maow Maalin was a 23-year-old working as a hospital cook in the port of Merca, #Somalia.

In addition to his duties in the kitchen, Maalin had worked as a vaccinator in WHO’s #smallpox eradication programme, which had hunted down the last remaining cases of smallpox……
@DrTedros "In October of that year, two children with #smallpox from a nomadic group were sent to an isolation camp near Merca. The driver who was transporting them stopped at the hospital where Maalin worked to ask for directions.

Maalin offered to accompany them. The driver asked if he……
Read 51 tweets
Dr Edward Jenner, who invented vaccination, died 200 years ago today. Jenner created the first-ever vaccine when he found out people infected with cowpox were immune to #smallpox. This discovery ultimately led the world to eradicate this deadly disease & save millions of lives ⬇
At first, not everyone agreed with Dr Jenner and his #smallpox vaccine. Rumours & #misinformation circulated at the time that the vaccine would turn people into cows.

📸 @WellcomeLibrary
#Smallpox was eradicated in 1980, thanks to an extended global effort, spearheaded by WHO and involving all countries. Thousands of #healthworkers administered half a billion vaccinations to stamp out the disease. #VaccinesWork
Read 5 tweets
Two #smallpox #vaccines may be used for #monkeypox: efficacy unknown. In the U.S. now the Norwegian JYNNEOS 2-dose vax is used for #MPX but it's assumed prior ACAM2000 Sanofi smallpox vax protects.
Here, the case of an ACAM2000-vaxed man who got MPX.
"We report a patient in Washington who contracted #monkeypox despite being successfully immunized against #smallpox with the ACAM2000 #vaccine 8 years earlier.
The patient was a previously healthy 34-year-old man who had sex with men...came to a clinic because of..."
3/ "...a 4-day history of malaise, fatigue & headache & 4 painless penile lesions.
"...this case highlights that #vaccination alone does not guarantee immunity from #monkeypox. Public health leaders should taper expectations that vaccination alone will end the outbreak."
Read 4 tweets
The @WhiteHouse #monkeypox #MPX briefing was mostly very good news. New cases reports are way down across most of the US, and globally. But in the last week the demographics shifted, from a predominately white male outbreak to:
- 38% black men
- 25% Hispanic
- 26% white
About 540,000 doses of #Jynneos #vaccine have been admin'ed in USA, and some men are now getting their 2nd doses -- which are essential for effective protection.
But there is a mismatch.
While 38% of new cases are black men, only 12% of vax uptake is in that group.
The @CDCgov is shifting from from education/#vaccination campaigns at large gay pride events, to smaller, targeted efforts aimed at less-served groups.
Meanwhile, CDC says MPX "travels with" other STDs & #HIV -- 61% of diagnosed #monkeypox cases are co-infected.
Read 7 tweets
Updated #monkeypox vaccines & immunization guidance:

📌 Vaccines and immunization for monkeypox: Interim guidance
What's 🆕

1⃣Men who have sex with men reinforced as group at high risk, are recommended for vaccination 💉

2⃣Revised terms:
Instead of pre-exposure prophylaxis (PrEP) 👉 use primary preventive vax (PPV)

Instead of post-exposure prophylaxis (PEP) 👉 use post-exposure vax (PEPV) A vaccine vial is on a black table.
What’s the same:

1⃣ Mass vaccination is still not recommended for #monkeypox at this time.

2⃣ Maximum immunity is usually reached 2 weeks after a complete series of vaccination. In the meantime, it is important to continue protecting yourself & others against monkeypox. A man is wearing an orange polo-shirt and a mask. He is layi
Read 5 tweets
1/🧵 MonkeyPox, ChickenPox, SmallPox:

Let’s talk poxpoxpox…
✔️#MonkeyPox has 4 deaths
✔️Is it a panedmic?
✔️What do you need to know?
✔️Here are key take homes
2/ Many people are holding off calling #MonkeyPox a pandemic.
Epidemics that “get passports” travel.
Mpox seems to have a global passport.
Sustained spread in >80 countries seems likely.
3/ The window for controlling Mpox is closing - eternal optimists are hoping enough vaccination can beat it.
Judging by how we handled #COVID, I’m betting Mpox will win.
@DrEricDing @kavitapmd make great points:
Read 18 tweets
A partir de hoy los informes de vigilancia epidemiológica de #RENAVE @SaludISCIII sobre #monkeypox se colgarán en:… #ISCIII #NoticiasISCIII vía @SaludISCIII
Informe de hoy: más de 2300 casos. Casi todos siguen siendo hombres pero hay 20 mujeres. Edad desde los 3 a los 76 años. 46% 🇪🇦, 25% latinos..
Madrid y Cataluña siguen siendo el epicentro del brote en 🇪🇦
Read 12 tweets
Fernando Simón en @ranm_es #monkeypox: "lo más probable es que este brote no se extenga mucho más allá en el tiempo". "Un infectólogo podría haber diagnosticado una lesión individual en la mano de un paciente" #siespecialidadEEII @SEIMC_
"Esto no ha pasado por casualidad, vivimos en un mundo cada vez más pequeñito" #OneHealth
Paz Sánchez Seco:"la prueba diagnóstica se desarrolló originalmente para diagnóstico de viruela en el contexto de un ataque #CBRN"
Read 9 tweets
Multi-country #monkeypox #outbreak: situation update

780 laboratory confirmed cases of monkeypox have been reported to or identified by #WHO from 27 Member States across four WHO regions that are not endemic for monkeypox virus.
#Monkeypox outbreaks in endemic countries in the #African región, 2022.

1408 suspected and 44 confirmed cases including 66 deaths were reported from seven endemic countries
WHO #Risk assessment: MODERATE considering this is the first time that many #monkeypox cases and clusters are reported concurrently in non-endemic and endemic countries in widely disparate WHO geographical areas.
Read 9 tweets
Was muss ich über #Affenpocken wissen?

1. Was sind Affenpocken❓

Affenpocken sind eine seltene, vermutlich vor allem von Nagetieren auf den Menschen übertragene Viruserkrankung. Übertragungen von Mensch-zu-Mensch sind selten, aber möglich, vor allem bei engem Kontakt.
#Affenpocken werden ausgelöst durch das Affenpockenvirus Orthopoxvirus simiae (auch #Monkeypox virus, #MPXV) aus der Gattung Orthopoxvirus. Das Virus ist verwandt mit den klassischen humanen Pockenviren (Variola, #Smallpox)
#Affenpocken beim Menschen wurden erstmals 1970 in der Demokratischen Republik Kongo bei einem 9 Monate alten Jungen identifiziert.
Im Frühjahr 2003 kam es zum ersten Nachweis von Affenpocken außerhalb des afrikanischen Kontinents.
Read 13 tweets
Why I feel we will have a much bigger outbreak of #MonkeyPox & top 70 updates ( we had 50 yesterday ) in the thread below . Let's start by what we already know & then go further

51/n Spain is seriously looking at whether the 80K strong LGBT community get together was a super spreader , they are also trying to find if one of the Saunas ( where gay men go for sex) has been the source , so the consequences are not due to genital spread but congregation ctd)
52/n The problem is its large number of likely reservoirs and things we probably can't entirely avoid including animal droppings : rats, mice, squirrels, shrews, opossums, ground hogs etc . So once it gets into a geographical location #monkeypox will be a tough nut ctd)
Read 21 tweets
#ฝีดาษลิง #monkeypox จริงๆเป็นคำเรียกที่ผิด (misnomer) นะครับ แต่เรื่องจาดเจอครั้งแรกในลิงเลยอนุโลม เอาเข้าจริงเราเจอมากในสัตว์ฟันแทะ (เช่น หนู) เมื่อเกือบ 20 ปีที่แล้ว มีการระบาดของฝีดาษลิง 47 คนที่อเมริกาเนื่องจากนำหนูแพรรี (prairie dog -รูป) จากประเทศกาน่ามาเลี้ยง ครั้งแรก 1/ Image
ที่เรารู้จักฝีดาษลิงย้อนไปหลายสิบปี 1958 แต่มาพบในคนเมื่อ 1970 ที่คองโก โรคนี้มีไข้ ตุ่มหนอง และต่อมน้ำเหลืองโต ถ้าไม่มีอาการแทรกซ้อนก็สามารถหายได้เอง ในอดีตเมื่อมีผู้เสียชีวิตจากฝีดาษลิง แต่นั่นต้องคิดว่าเป็นหลายสิบปีที่แล้วซึ่งการแพทย์ยังไม่พัฒนามาก หลังจากการระบาด 2/
ครั้งแรกที่ดูเหมือนมีคนเสียชีวิตมากหน่อย ก็มีการระบาดประปรายในแอฟริกา แต่มีคนตายลดลง แต่ระบาดนอกแอฟริกาครั้งแรกที่อเมริกา 47 เคสดังที่ผมเล่าให้ฟังข้างบนไม่มีผู้ใดเสียชีวิต (มีผู้ป่วยป่วยเด็กที่มีอาการหนัก 2 รายแต่รอดชีวิต) ผู้ติดเชื้อเกือบทั้งหมดสัมผัสหนูแพรรี่ หรือที่อยู่มัน 3/
Read 9 tweets
As far as The Third Strain of #MonkeyPox, the cure can be found within Planet Of The Apes #OR CONGO …

If you should happen to come down with #SmallPox Strain Number 3, Find ‘Tarzan’ & ask him for help …
Tarzan is the only one who can/is allowed to Swing from Branch to Branch
Within the Biblical Bloodline Tree of life …
Tarzan keeps the peace with ALL Biblical Bloodline Families on EVERY branch, including the TRUNK of the Tree …
Tarzan = Pure

Read 5 tweets
Mousepox, caused by orthopoxvirus ectromelia virus, closely related to #smallpox only infects mice. In mice it causes a mild illness. In 2001 Australian scientists were developing a contraceptive vaccine for mice. But it killed all the mice. (Thread)…
The vaccine was to help control mouse breeding and reduce agricultural damage . They used ectromelia virus as a vector to carry mouse egg proteins so the mice would develop antibodies to their own eggs and thereby become infertile.
They inserted a gene for production of interleukin-4, a cytokine that stimulates the immune system, hoping this would accelerate the production of antibodies. When they vaccinated the mice with smallpox vaccine (which also protects against ectromelia virus),
Read 6 tweets
Monkeypox is an Orthopoxvirus like Small Pox or Vaccinia virus. They are brick shaped linear dsDNA viruses that replicate in cytoplasm. They bind to glycosaminoglycans to enter cells or are taken up by apoptotic mimicry #monkeypox #orthopoxvirus 1/n…
Small Pox is the archetypal orthopoxvirus infection of humans which infected humans from prehistory until its eradication in the 20th century through Vaccination. First true success of Vaccines 2/n #Variola #SmallPox #orthopoxvirus…
History of Small Pox Vaccination is the history of Vaccination itself. Life long immunity produced against Small Pox, which could be mimicked by attenuated cowpox (Vaccinia) was the key to Small Pox eradication 3/n #Vaccinia #SmallPox #orthopoxvirus…
Read 37 tweets
MPX is an orthopoxvirus closely related to #smallpox. It has 2 clades- the milder one has a fatality rate similar to #SARSCoV2 - the other, closer to SARS1 at 10%. UK outbreak caused by the milder clade. #monkeypox has surged since 2017 due to (thread)…
A combination of waning immunity from smallpox vaccines - mass vaccination stopped by 1980, when SPX declared eradicated; population growth and ecological factors as we explored…
Smallpox vaccines work against MPX, and also work as post-exposure prophylaxis in a strategy devised during the eradication campaign called "ring vaccination" because of a long incubation period.…
Read 7 tweets
LIVE: Media briefing on #COVID19 and other global health issues with @DrTedros…
"Over the last week, #COVID19 cases have risen in four out of the six WHO regions. Due to testing and sequencing reducing in many countries, it is increasingly difficult to know where the virus is and how it’s mutating"-@DrTedros
"The Democratic People’s Republic of Korea has announced, through their state media, their first outbreak of #COVID19, with more than 1.4 million suspected cases since late April"-@DrTedros
Read 31 tweets
The UK #monkeypox outbreak is very interesting. A 🧵of some key points
- typically very limited human-to-human transmission, needs very close contact
- therefore, transmission is nothing like #COVID19
- to add to other #publichealth voices, very very low risks to wider general public
- if close contact, then public health teams will follow up
- monkeypox can be very nasty (case fatality rates upwards of 1%, albeit most outbreaks in areas where healthcare is v limited)
- UK has several specialist facilities for handling unusual tropical medicine cases. NHS is very good at this.
- Name is a bit misleading. First identified in monkeys, but small animals like rats/other rodents a more common host (typically in parts of West/Central Africa)
Read 12 tweets
It’s #WorldImmunizationWeek!

If you could see viruses you would know that they are all around. Vaccines provide opportunity and hope for all of us to enjoy ​a more fulfilling life. ​That's something we should all be fighting for.​ Vaccines, in the pursuit of a #LongLifeForAll.
This #WorldImmunizationWeek, let's celebrate life’s relatable moments that make us happy to be alive.
Dinner with friends.
A first kiss.
A first dance.
An early start to the day.
A family reunited.

#LongLifeForAll Image
Ever since the 1st vaccine was developed for #smallpox in 1796, the 🌍 has seen their unparalleled impact on health and wellbeing. People have been vaccinated for centuries, leading to the eradication of smallpox and driving down polio cases to an all-time low. #LongLifeForAll Image
Read 9 tweets
Daily Bookmarks to GAVNet 12/09/2021…
Merck's COVID-19 pill significantly less effective in new analysis…

#COVID19 #pill #effectiveness
The superfoods that fueled ancient Andeans through 2,500 years of turmoil…

#IndigenousDiets #superfoods #agriculture #EnvironmentalImpact
Read 13 tweets
Daily Bookmarks to GAVNet 11/28/2021…
Smallpox vials found at Montgomery County lab, but ‘there is no basis for being worried’…

#smallpox #laboratories #InfectionRisk
Satellites offer new ways to study ecosystems—and maybe even save them…

#RemoteSensing #SatelliteTechnology #EcosystemsHealth #CorrectiveAction
Read 13 tweets

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