Andreas Charidimou MD, PhD Profile picture
Jun 16, 2022 15 tweets 12 min read Read on X
📌How to design a brain 101🧠🏗️

A 🧵 on how I use @powerpoint to create illustrations

🎨Key tools and my 2 secret weapons:

-@gboulouis adding "advanced" stuff
-@MVarkanitsa reviewing every little detail

#MedTwitter #MedEd #NeuroTwitter #NeuroRad #Neurology #neuropath #FOAMed
This 🧵 is inspired by a great recent post from @teachplaygrub, since we are using similar methods and tools on #PowerPoint!

🛠️ The Basic Toolkit:
-curve function ➰
-edit points function✴️
-Layering 🃏
-Zooming (x300-400%) for details 🔍

🎨 colors, shadows, 3D effects etc., depends on individual's style

1/
♾ It's important think the"reverse engineering" of these illustrations, to better realize that they are:
-multicomponent
-multilayered

➡️See for example the brain schematic on Cerebral Amyloid Angiopathy brain features: made of many individual shapes, figures and layers...

2/
To break this down, let's see how to design only a part of the brain 🧠: a piece of the cortex and some small vessels

#MedStudentTwitter #MedEd #FOAMed #tweetorial #FOAMrad #Neurology #Neurosurgery #RadEd #illustration #PowerPoint

3/
👉🏿This illustration is in fact comprised of 4 individual elements (some are groups) that are created separately, but with the final piece in mind.

(I usually sketch🖌️ on paper w pencils the basic drawing that I aim to create, to get the general idea)

4/
Step 1: Curve tool - gives enormous control for drawing the basic shapes you need

➰Now, I have created the basic shape for the cortex 👇🏿

I will do a similar, but smaller shape for the white matter...

5/
Step 2: add color🎨("Shape fill" tool) and outline
(you can do fancy things like gradient fills, shadows, 3D, but let's go with a simple fill)

Step 3: layering🃏- you overlay shapes to create the whole

Now a basic piece of cortex and some white matter is taking shape..👇🏿

6/
Step 4: Correction of details with the "Edit points" tool under magnification

**each shape is comprised of individual connected points, you just don't normally see them!

I use this to make small alterations to shapes: change curvature of points, angle, add/delete points...

7/
Step 5: To create the blood vessel, I use again the Curve tool under magnification to make the outline of the shape, in this case a penetrating arteriole.

... add color, outline, edit points PRN

See for example a smaller arteriole in the making👇🏿
(you can sprinkle VEGF)

8/
As you would imagine, the more elaborate a shape is, the more painstaking the process of modifying the points is...

9/
In some illustrations or parts of them, if I aim for #Anatomy #neuropath #NeuroRad #biological accuracy, I might consult an atlas or an actual photo.

This is what I used for example to design the #cortical layers 👇🏿

10/
⚫️ Now, just for fun, let's add some @microbleeds in the cortex.

I draw a circe, paint it black, add a bit of black glow to represent the blooming effect on blood-sensitive MRI, make copies, and add them to the illustration 👇🏿

11/
🧠🏗️ And this is how you build a brain, piece (of cortex) by piece...

I use more or less the same method for more complicated illustrations.

I hope you find this helpful!

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More from @a_charidimou

Mar 10
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Don't panic! 😱

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2/10
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@Ellis_van_Etten provided a clinical update on CAA-ri
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➡️What's happening?

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