Long Thread on Health Risks with Reinfection . While the Herd Immunity brigade has been pushing their agenda,we need to understand the risk of multiple reinfections .It is an interesting cohort with 12.29% with 2 reinfections 0.76% with 3,.08 with 4 ctd).doi.org/10.21203/rs.3.…
Ctd2)Clearly the time for reinfections is getting shorter 79 for 2nd to 65 days for 3rd & so on.Also the hazard is not only to the lungs BUT also to heart,blood vessels ,Gastrointestinal systems, kidney , the brain, the soft tissues and bones & the brain in that order ctd)
Ctd3) clearly if you are not vaccinated you are at higher risk BUT only vaccination isnt enough #VaccinePlus strategy is important , the risk remains high for 6 months with measurable reduction every 30 days BUT we are getting reinfected in that period (now 65 days ) ctd)
Ctd4)Compared to 3 infections those infected twice had 30% lesser risk ,& 1 infection had 60% + lesser risk of sequelae including mortality , hospitalizations & #LongCovid.So makes sense to prevent sequential issues.Science will catch up eventually with better tools ctd)
Ctd 5) This brings me to final question- What do we do ?? - 1) Mask with #N95 as a principle in public places 2) Get boosted 3) advocate updated vaccines 4) Advocate early treatment & take it 5) advocate for clean air 6) get kids vaccinated 7) help people understand the risk 🙏

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More from @Rpshahmemorial1

Jun 22
Why are we going to see an avalanche of infertility,problems in conceiving in the next couple of years?? Well this is a 500 plus young men less than 29 yrs cohort in swiss army who were evaluated & higher incidence of lipid issues,pre -diabetes found ctd)
doi.org/10.1101/2022.0… Image
Ctd2 we already know from past studies that 26% of young take more than 2 weeks to be " Normal", interestingly this one study used a larger number of parameters to prod a little more than others ctd) ImageImage
Ctd3)They used diffusion studies in addition to standard spirometry, PRO-BNP & Troponin to evaluate cardiac function,test on treadmill to stress the system,sniffing tests , eye tests, taste tests, psychological tests, sperm count & testosterone levels in post #Covid males ctd) ImageImage
Read 5 tweets
Jun 19
Was talking to a physician colleague 50/M who said he has increased incidence of migraine like attacks lately and also reported a bad #Omicron bout 4months ago that caused him bed bound with weakness 1 week , cough for 3 weeks.Then while discussion he casually described ctd)
Ctd2) That after 3 months of the infection he faced a peculiar situation- for 4 days he was trying to remember the name of anti fibrotic agent , he said he could have easily opened the book or internet and checked BUT he wanted to assess , the antifibrotic he was trying to ctd)
Ctd3) remember he has used in at least 300 pts during the wave 3 months before & at least 500 overall , still his memory was failing him for 4 full days ,he also reported that he is unable to remember the songs that he was singing on & off which he loved ,remembered earlier ctd)
Read 5 tweets
Jun 6
1/Prolonged discussion with Pediatric colleagues in the core group @Rpshahmemorial1- findings - we are having increased incidence of red eye, apthous ulcer ,recurrent fever every month & Lymphopenia like this in kids , we will watch this but we are very concerned #COVID19 ctd)
2/ Though it is currently anecdotal information we hope that in a day or two we will be able to collate more data on this , most of these kids turn out to be negative on testing BUT have had family members who were positive in the recent period , others ctd)
3/n in the core group noted that apthous ulceration has increased multi fold over the last 1.5- 2 years and so have red eye syndrome , in many these kids are an overlap group. There is also anecdotal information of vague joint pains which appear like post reactive synovitis.
Read 4 tweets
May 31
Top 225 updates on #monkeypox, we posted until 200 here , again posting them & will start a thread from 201 onwards below this tweet
Here you go ....
201/n @mdc_martinus posted how #PublicHealthOntario accepted potential for #airborne transmission of #monkeypox, agree that this is the correct public health policy ctd)
202/n @BNODesk reported 134 cases globally today with the peak crossing the previous high of 100 , globally 700 plus cases ctd)
Read 21 tweets
May 28
After touching 175 we will try and keep everyone updated about #monkeypox, will post the 175 first followed by the updates all the way till 200 .Here we go
Updates below ctd)
176/n @karmonyk has graciously shared a story, these delays have cost the patient the chance to prevent a bad outcome , vaccine best within 4 days and works all the way till 2 weeks , we've lost that window period , we are up for a bad outcome if we treat #monkeypox this way ctd) Image
177/n As Argentina logs up its second case, Mexico joins the league logging its first one ctd)
Read 26 tweets
May 26
151/n Germany has ordered 40,000 doses of a Bavarian Nordic vaccine to be ready to vaccinate contacts of those infected with monkeypox.Rest 150 news here ctd)
152/n Spanish woman tests positive for monkeypox, the 1st woman to be conclusively linked to the outbreak ctd)
153/n First case of monkeypox in a school aged child was confirmed in Quebec. And no, they did not isolate the class. That’s a really poor decision. Ctd)
Read 26 tweets

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