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Raina MacIntyre 😷💉📈 Profile picture
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Jul 18 • 4 tweets • 2 min read
AHPRA's made a serious mistake in trying to silence Dr David Berger - Medical Observer - #AusDoc ausdoc.com.au/opinion/ahpras…

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More from @Globalbiosec

Raina MacIntyre 😷💉📈 Profile picture
Jun 21
I and another family member had COVID last week despite being fully vaxxed, and was worried about a vulnerable family member that I am sole carer for. I protected them from infection by universal #N95 use at home, windows open (brrrr) and air purifiers running 24/7. 1/2
I also checked my RAT daily to monitor how infectious I was (a negative RAT is a good indicator u r not infectious). I also had a private prescription for AVs which cost $1200. All these things were expensive - the air purifiers, the N95s, the RATs.
When people cite "freedom" and "choice" or pour scorn on those of us who mask or who seek to protect vulnerable loved ones, freedom and choice are a privilege available to those with means.
Read 6 tweets
Raina MacIntyre 😷💉📈 Profile picture
May 19
Mousepox, caused by orthopoxvirus ectromelia virus, closely related to #smallpox only infects mice. In mice it causes a mild illness. In 2001 Australian scientists were developing a contraceptive vaccine for mice. But it killed all the mice. (Thread) newscientist.com/article/dn311-…
The vaccine was to help control mouse breeding and reduce agricultural damage . They used ectromelia virus as a vector to carry mouse egg proteins so the mice would develop antibodies to their own eggs and thereby become infertile.
They inserted a gene for production of interleukin-4, a cytokine that stimulates the immune system, hoping this would accelerate the production of antibodies. When they vaccinated the mice with smallpox vaccine (which also protects against ectromelia virus),
Read 6 tweets
Raina MacIntyre 😷💉📈 Profile picture
May 18
MPX is an orthopoxvirus closely related to #smallpox. It has 2 clades- the milder one has a fatality rate similar to #SARSCoV2 - the other, closer to SARS1 at 10%. UK outbreak caused by the milder clade. #monkeypox has surged since 2017 due to (thread) wwwnc.cdc.gov/eid/article/27…
A combination of waning immunity from smallpox vaccines - mass vaccination stopped by 1980, when SPX declared eradicated; population growth and ecological factors as we explored wwwnc.cdc.gov/eid/article/27…
Smallpox vaccines work against MPX, and also work as post-exposure prophylaxis in a strategy devised during the eradication campaign called "ring vaccination" because of a long incubation period. tandfonline.com/doi/full/10.10…
Read 7 tweets
Raina MacIntyre 😷💉📈 Profile picture
May 10
Let's talk about the mystery epidemic of #hepatitis in children. It's most likely a complication of #COVID19 but may take a while to be adjudicated as such. The syndrome has been seen in children <17, mostly unvaccinated kids <5 years. A thread.
Hepatitis is a known presentation of #MISC onlinelibrary.wiley.com/doi/10.1111/ij… & MISC is a late complication, after the acute infection. So, the fact that PCR is negative is not surprising.
Also, kids do not have as robust an antibody response as adults so may be -ve on serology too. nature.com/articles/s4159…
Read 12 tweets
Raina MacIntyre 😷💉📈 Profile picture
Mar 17
A lot of defeatist chatter about the small 4th dose trial published in @NEJM. A thread on interpretation. 3rd dose protection wanes substantially. Note, the Y axis is a log scale, so small differences are actually large differences. 1/5 nejm.org/doi/full/10.10…
The 4th dose restored waned immunity to the same level or higher than early after dose 3. That's good, because without dose 4, there is little protection. The VE against symptomatic infection was 31-43%. On a population level, this is important. 2/5
The 11-30% VE against any infection will make a substantial impact on transmission at a population level. The impact of vaccines is a function of VE, coverage and incidence of infection. When incidence is high, even a vaccine of modest VE can have a major population impact. 3/5
Read 8 tweets
Raina MacIntyre 😷💉📈 Profile picture
Dec 17, 2021
NSW should immediately reinstate mask mandates, QR codes, contact tracing, and 3 day home isolation for international travellers. Abandoning everything while Omicron takes over and cases surge to unprecedented levels is more than a mistake. It is reckless. 1/3
Data not clear that Omicron is less severe and still emerging. See Even if Omicron less severe, 25K cases a day means the health system will collapse if even a small % need hospitalisation. Loss of protection of 2 doses of vax will negate ↓ severity
Those who got AZ are most at risk because protection against symptomatic infection drops to 5.9% after 2 doses according to UK data. About 34% for Pfizer. khub.net/documents/1359…
Read 7 tweets

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