Raj Rajnarayanan Profile picture
Oct 7, 2022 14 tweets 13 min read Read on X
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

18.5% BA.5.2.1
15.4% BA.5.2
12.0% BA.4.6
10.3% BA.5.1
3.6% BF.10
3.2% BA.5.5
2.6% BA.5.2.9
2.6% BA.5.6
2.0% BA.5
2.0% BF.7

Tracker: tinyurl.com/mryj4uu7

#OmicronUpdates 10/06/22
1/n
Top circulating lineages (#15DayTrends)

80% BA.5*
12% BA.4.6*
2% BF.7*
1.5% BA.4*
1.3% BA.2.75*
1.1% BQ.1*
0.9% BQ.1.1*
0.3% BA.2.3.30*
0.1% XBB*

2/n
.@CDCgov updated variant proportions estimates on 9/30/2022



3/n
Lineages to watch

BQ.1*/BQ1.1*
BA.2.75.2* ( & CA.1*)
XBB - Recombinant of BJ.1 and BM.1.1.1
BA.2.3.20



4/n
The Great Convergence!

Key #Spike amino acids tracked: 346, 356, 444-446, 450, 452, 460, 486, 490, 493-494



5/n
Updates from #LineageWatchTeam's @GenSpectrum
#Collection24 maintained by @siamosolocani
/@Asinickle1

>> All eyes on BQ.1*/BQ.1.1*, BA.2.3.20, XBB and BA.2.75* lineages <<

Collection24: cov-spectrum.org/collections/24…

Tracker: public.tableau.com/app/profile/ra…

(#15DayTrends - #USA)
6/n
Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/hospitalizations.

Please get #boosted ASAP!

public.tableau.com/app/profile/ra…

7/n
#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

8/n
#COVID19 #Hospitalizations in the #UnitedStates

Please get #boosted (especially > 50 yr old and immune compromised) and #MaskUP!

Hospital Tracker (by States, by age group): public.tableau.com/app/profile/ra…

9/n
Closely watching #COVID19 #Hospitalizations in > 50 years old in #USA

Get #Boosted ASAP!

10/n
Closely watching #Pediatric #COVID19 #Hospitalizations in #USA

11/n
#COVID19 #Cases and #Deaths - US States
- @CDCgov data

Tracker: public.tableau.com/app/profile/ra…

12/n
Status of the latest #COVID19 Wave in #NewYork #BellwetherState

Top circulating variants - BA.5.2.1 (17.8%), BA.4.6 (14.9%), BA.5.2 (13.8%)

Other key lineages
BF.7 (3.6%)
BQ.1* (3.3%)👀
BQ.1.1* (1.8%)👀
BE.1.1.1* (0.7%)

Don't let your guard down!

13/n
Status of the latest #COVID19 Wave in #Massachusetts

Top circulating variants - BA.5.2 (18.7%),BA.5.1 (16%), BA.4.6 (9.3%)

Other key lineages
BQ.1.1* (1.3%)
CA.1* (1.3%)

(not many sequences with sample collection dates in the last 15 days)

Don't let your guard down!

14/n

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Raj Rajnarayanan

Raj Rajnarayanan Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @RajlabN

Jan 6
The Louisiana Department of Health reports the patient who had been hospitalized with the first human case of highly pathogenic avian influenza (HPAI), or H5N1, in Louisiana and the U.S. has died.

katc.com/news/covering-…Image
Note: This is H5N1 Avian Influenza A #WildBird -D1.1 genotype and not #DairyCattle B3.13 genotype related
Read 4 tweets
Jan 1
#H5N1 #AvianInfluenza updates

New @NEJM case report describing severe human illness caused by highly pathogenic avian influenza A -H5N1 in #BritishColumbia (#Canada) teenager with evidence of potential viral adaptation to humans.



1/n nejm.org/doi/full/10.10…Image
A 13-year-old girl with mild asthma and obesity (BMI >35) presented with conjunctivitis, fever, respiratory distress, and multi-organ complications was hospitalized on 11/7/24, and required intensive care, including ECMO and continuous renal therapy

2/n
RT-PCR confirmed A/H5N1 infection, and the virus was linked to wild birds in British Columbia.

Genetic analysis revealed mutations in the HA protein (E186D, Q222H), associated with increased binding to human airway receptors, facilitating viral entry and replication.

3/n
Read 6 tweets
Dec 22, 2024
#H5N1 #AvianInfluenza updates

Quick analysis of the 7 sequences from NIAID experimental study of #Macaques infected w/ H5N1 2.3.4.4b (B3.13 type)

PB2 mutations: T58A, V109I, V139I, E362G, K389R, D441N, V478I, V495I, M631L, V649I, M676A, E677K

Ref: A/Duck/Guangdong/E1/2012

1/n
HA mutations: L120M, L131Q, T211I, V226A, I526V

Ref: A/Astrakhan/3212_cell/2020

2/n
NA mutations: V67I, D259E, L269M, V321I, S339P

Ref: A/AmericanWigeon/SouthCarolina/22-000345-001/2021

3/n
Read 4 tweets
Oct 20, 2024
Tracking #SARSCoV2 #Lineages - Globally |10/19/24

Top lineages -#30DayTrends #G30

KP.3.1.1 (41.9%)
XEC (10.5%)👀
KP.2.3 (3.1%)
MC.13 (3.1%)
MC.16 (2.6%)
MC.1 (2.5%)
KP.3.3 (2.3%)
LB.1.3.1 (1.9%)
MC.10 (1.7%)
MC.11 (1.4%)
XEC.2 (1.3%)👀



1/n public.tableau.com/app/profile/ra…Image
Granular details #Global #30DayTrends

KP.3.1.1* is still the top circulating group of lineages in the world.

This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 09/19/2024 (11,851sequences)

2/n Image
@GISAID Thanks to all the countries that are supporting #SARSCoV2 testing and rapidly submitting sequences to @GISAID

Top submitters #Canada #USA #France #UK #Netherlands #Sweden #Spain #Japan #Italy
#Denmark #Australia #Ireland #Singapore
#China #NewZealand #Slovenia #Germany

3/n Image
Read 4 tweets
Sep 27, 2024
#SARSCoV2 #VariantProportions - #USA |09/27/24

@CDCgov #Nowcast 2-Week estimates

KP.3.1.1 (JN.1.11.1.3.1.1) is still the top circulating lineage in the USA

🚨XEC makes an entry @ 5.7%



1/n covid.cdc.gov/covid-data-tra…
Image
Reliable nowcast estimates are available only for HHS regions 2, 3, 4, 5, 7 and 9

Other regions did not sequence enough

2/n Image
KP.3.1.1* group of lineages

In the @CDCgov nowcast chart....
KP.3.1.1* is not further separated in to MC.1-MC.16 sub-lineages

3/n Image
Read 6 tweets
Sep 8, 2024
Tracking #SARSCoV2 #Lineages - Globally |09/07/24

Top lineages -#30DayTrends

KP.3.1.1 (37.1%)
KP.2.3 (9%)
KP.3.3 (5.7%)
KP.3.1 (2.9%)
XDV.1 (2.9%)
KP.1.1.3 (2.7%)
LB.1 (2.3%)
LB.1.3 (2.1%)
KP.2.2 (2%)
---
XEC (1.4%)👀

Track #G30 :

1/n public.tableau.com/app/profile/ra…
Image
Granular details #Global #30DayTrends

KP.3.1.1* is still the top circulating group of lineages in the world.

This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 08/08/2024 (12,884 sequences)

2/n Image
@GISAID Thanks to all the countries that are supporting #SARSCoV2 testing and rapidly submitting sequences to @GISAID

Top submitters #USA #Canada #UK #Sweden #Japan
#China #Spain #Australia #Germany #Denmark #SouthKorea #France #Singapore #NewZealand #Ireland #Italy #Netherlands Image
Read 16 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(