Discover and read the best of Twitter Threads about #Spike

Most recents (11)

#COVID19: ACTUALIZACIÓN NOVIEMBRE 2020

Desde la nueva vacuna fase 3 de #Pfizer hasta las #reinfecciones, #secuelas e #inmunidad.

Hoy les hablare sobre lo que nos ha dado al evidencia científica al respecto de estos temas, pero lo haremos con memes de #BobEsponja.

Abro hilo 🧵
De acuerdo a la revista médica #TheLancet, se define como evidencia científica al uso consciente, explícito y juicioso de datos válidos y disponibles procedentes de la investigación científica, con lo que podemos tomar decisiones clínicas.

Algo así como LA CARACOLA MAGICA ✨
¿CUÁNTO TIEMPO DESPUES PUEDE CONTAGIAR UNA PERSONA QUE PRESENTÓ #COVID19?

#ContagioCOVID19 🦠
Read 60 tweets
À propos de #mutations du #SARSCoV2 chez les #Visons au #Danemark peu d'infos et, au minimum, une communication catastrophique. Deux threads détaillés de @firefoxx66 et @BallouxFrancois qu'on résume en français 1/10 Thread
threadreaderapp.com/thread/1324085…
threadreaderapp.com/thread/1324095…
Les visons sont, comme beaucoup de mammifères, infectés par le #SARSCoV2 avec des symptômes légers. Les élevages peuvent donc être un réservoir. Et, pour la grippe aviaire, l'homogénéité génétique des animaux d'élevage favorise les souches virulentes. 2/10
adioscorona.org/themes-questio…
Il y a déjà eu des épidémies de #SARSCoV2 dans des élevages de visons aux Pays-Bas en juin qui ont conduit à des abattages massifs à cause des passages à l'homme (on a estimé que 50.000 infections ont été indirectement liées à ces élevages). 3/10
sciencemag.org/news/2020/06/c…
Read 10 tweets
There are reports coming out in the Danish media of novel mutations emerging in #SARSCoV2 in #mink tinyurl.com/y5gbwype

SARS-CoV-2 can infect multiple mammalian carnivores and has now been detected in multiple mink farms to date 👇
Across high coverage #SARSCoV2 genomes isolated from mink @GISAID we pick up unique mutations including one in the #spike protein which has appeared at least five times in phylogenetically distant #mink lineages. Image
This mutation, falling within the receptor binding domain, may be a good candidate for adaptation of #SARSCoV2 to #mink hosts. While this mutation has been seen in #SARSCov2 in human circulation it is rare. Currently available mink genomes fall in the diversity of human #SARSCoV2
Read 4 tweets
🔥Thread sur le cocktail d'anticorps REGN-COV2 que reçoit Trump. Des résultats ont été publiés le 30/09 par Regeneron suite à analyse intermédiaire.

investor.regeneron.com/index.php/news…
Il s'agit d'un cocktail de 2 anticorps monoclonaux REGN-33 et REGN-87 qui ciblent précisément la protéine #Spike du #SARSCoV2 et permettraient d'empêcher l'entrée du virus dans la cellule.

Cible thérapeutique très prometteuse
D'après Regeneron, environ 2000 patients sont inclus dans des essais cliniques visant à tester ce traitement.

On voit que #Recovery du @NIH a inclut ce cocktail dans leur essai clinique
Read 14 tweets
Incroyable comme prescription et je trouve assez inconséquente

Polyclonal antibodies (quasi aucune données publiées) + melatonine (rien vu dessus ?) + famotidine (1 étude observationnelle) + aspirin (peut être au long cours) + zinc (?) + vit D (?) + remdesivir (ajouté depuis) ?
Franchement s’ils rajoutent Azithromycine et Hydroxychloroquine c’est pas la maladie qui va le tuer.

Ses médecins ont pas du lire #ToomuchMedicine @ABIMFoundation #lessismore @UKchoosewisely
Pour être précis, il s'agit de REGN-COV2 qui est un "cocktail" de 2 anticorps monoclonaux qui ciblent la protéine #Spike du #SARSCoV2

Polyclonal est un abus de langage.

investor.regeneron.com/index.php/news…
Read 3 tweets
Abbiamo ormai imparato in molti che il #coronavirus si lega a un particolare recettore chiamato #ACE2. Lo fa con una proteina detta #spike. Una interessante novità è che c’è un altro recettore che gioca un ruolo importante e che è diffuso sulle cellule anche più di ACE2 Image
È una proteina chiamata Neuropilina-1. (NRP1) Nelle cellule delle vie respiratorie sono presenti entrambi i recettori e per questo il virus di lega molto bene.
Attraverso le cellule progenitrici dei neuroni dell’olfatto, che hanno molta neuropilina -1, il virus riuscirebbe poi ad arrivare al cervello coi danni neurologici che sempre più si stanno documentando.
Read 5 tweets
Daily Bookmarks to GAVNet 7/10/2020-2

greeneracresvaluenetwork.wordpress.com/2020/07/10/dai…

Structural analysis of COVID-19 spike protein provides insight into its evolution

phys.org/news/2020-07-a…

#vaccine #protein #spike
Mounting evidence suggests coronavirus is airborne — but health advice has not caught up

nature.com/articles/d4158…

#evidence #COVID19 #aerosol #coronavirus
The Damage We’re Not Attending To - Issue 87: Risk - Nautilus

nautil.us/issue/87/risk/…

#damage #coronavirus
Read 4 tweets
"The live SARS-like coronavirus SL-CoV-WIV1 has been isolated for the first time from bat droppings; and such virus has been confirmed to invade the host cells through the ACE2 of human beings..." ImageImageImage
Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964 ImageImageImageImage
In this study, we have developed a fast and cost-effective method
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily. ImageImageImageImage
Read 68 tweets
"La presencia de un gran reservorio de virus similares al #SARS-CoV en los murciélagos de herradura, junto con la cultura de comer mamíferos exóticos del sur de China, es una bomba de relojería."
Octubre de 2007. El resto es historia 👇 Image
Con este párrafo cerraban C. Cheng, S.K.P. Lau, P.C.Y. Woo, y K.Y. Yuen, de la Universidad de Hong Kong, su artículo científico titulado fue publicado en la revista CLINICAL MICROBIOLOGY REVIEWS en #Octubre2007
Es decir, desde 2007 se sabía del peligro de que un nuevo virus del tipo SARS-CoV pudiese saltar de animales a humanos y provocar una pandemia, como así ha sido. Todo pudo ser evitado, solo teníamos que haber escuchado.🤦‍♂️
Read 12 tweets
Like so many of the #DeepState illegalities, they get old before we learn the truth. I know @TheChillum has linked this to #FionaHill but I’m holding to my theory. Here’s why.
The @nytopinion appeared at a pivotal moment. Kavanaugh’s hearing was just part of it. Spike Lee’s BlackKlansman came out that weekend. This is perhaps the most racist, vindictive feature film ever produced, disguised as “equality” & “social justice.” google.com/amp/s/www.nyti…
In it, are direct & oblique references to @POTUS #MAGA. In one klan meeting, the audio picks up the phrase “Make America Great Again.” That should make every American angry, but not for the reasons #Spike thinks.
Read 9 tweets
So I’ve been wanting to be play this game..Finally going to do it... Image
1. (#Damon & #Elena) #Delena |You want a love that consumes you. You want passion and adventure, and even a little danger..#TVD
2. (#Liam & #Steffy) #STEAM | No one can stop us. You know why? Because we are written in the damn stars.
Read 140 tweets

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