RMR Profile picture
Nov 21, 2022 13 tweets 6 min read Read on X
Frontal lobe: anatomy, history, Edgar Allan Poe and beyond, why not?
🧠📝✍️🕵️

Part 1: gross anatomy

"All that we see or seem is but a dream within a dream." - E. A. Poe.

#Neurology #Anatomy #Teaching #EndNeurophobia #Neurotwitter

1/🧵 Phineas Gage
⚠️Disclaimer:
Due to the complexity of this structure, this tweetorial will be composed of three main parts.

1️⃣ Gross anatomy and microscopic anatomy (sort of)
2️⃣ Areas and connections
3️⃣ Clinical Syndromes and curiosities

Hope you enjoy!

2/🧵
⚠️Before we begin, a great quote about this amazing part of the human brain. 👇⬇️

3/🧵
What is the frontal lobe?🤔🤨

- Biggest cerebral lobe 🧠
- It occupies 1/3 of all the content inside the skull 💀
- It has multiple complex connections between structures 🥅

4/🧵
Limits ⛔

- Superior: Central Sulcus, Frontal Pole, Sylvian Fissure 🆙
- Lateral: Frontal Pole, Sylvian Fissure 💠
- Medial: Medial Portion of the Central Sulcus, Frontal Pole, Cingulate sulcus🛣️

5/🧵
Fissures give rise to different Gyri in the frontal 🧠. As 🥼🩺is much more easier and practical to learn functional areas, but as #AnatomyLovers it is important to know most of these concepts.

6/🧵
What about the cortex?🧠

- Neocortex in the brain has six layers 🧅
- The diffrerence between the thickness of these six layers is what makes a difference in function

A few examples:👇
7/🧵
Now that I mentioned function and functional areas. 🤓
We all know Brodmann, right?🤔

His model is based on the cytoarchitectonic structure of the cerebral cortex. 🔬

8/🧵
More recent studies using fMRI have discovered that areas are not the same for everyone and what it used to be a well divided map is now changing. 🤯🤯

As every human is different, it makes sense that functional areas are not exactly the same for everyone. 🤔

9/🧵
Below is a more "updated" map of the Functional Areas of the Frontal Lobe👇⬇️🔽

10/🧵
🤓Enough of Gross anatomy, but before we leave...🤪🤓
Do you know what is Exner's area function❓

Answer in the next thread.
Sources:
1.- Psychopathology. 2015;48(4):222-9.
doi: 10.1159/000381986
2.- Fitzgerald MJ, Greuner G, Mtui E. Clinical Neuroanatomy and Neuroscience,2012
3.- Handb Clin Neurol. 2019;163:95-122.
doi: 10.1016/B978-0-12-804281-6.00006-9
Sources:
4.- Science. 2017 Oct 27;358(6362):478-482.
doi: 10.1126/science.aan8868
5.- Brain. 2018 Nov 1;141(11):3262-3278.
doi: 10.1093/brain/awy273

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with RMR

RMR Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @MedinaRiojaMD

May 12, 2023
Atypical variants of motor neuron disease.

🧠🏥🏃

#Neurology
#Neurotwitter
#teaching
#Neuro
#MiniThread

Does the phenotype matter?

Yes, as prognosis is different in some variants.

1/🧵 Image
a) Spinal-Onset ALS
b) Progressive Muscular Atrophy
c) Progressive Bulbar Palsy/Bulbar-onset ALS
d) Facial onset sensory and motor neuronopathy (FOSMN)
e) Flail-arm syndrome (Vulpian-Bernhardt syndrome): LMN upper limbs and UMN (usually only brisk reflexes in lower limbs)
2/🧵
f) Hirayama disease: monomelic amyotrophy
g) O’Sullivan-McLeod syndrome: slowly progressive distal amyotrophy of the hands and forearms extending over long periods of time
h) Flail-leg syndrome
3/🧵
Read 5 tweets
Jan 1, 2023
Midbrain Syndromes: Parinaud, Weber, Benedikt, Claude and Nothnagel.
🧠🥸🤔

#NewYearNewThread

#Neurology #Anatomy #Neurotwitter #History

1/🧵
Before we describe the main characteristics of these syndromes, it is improtant not to forget the main structures present in this region. ⚠️

Note: this is not a neuroanatomy 🧵

2/🧵
Structures not to forget at this level:

1️⃣ Corticospinal tract: motor function (contralateral)
2️⃣ Oculomotor nucleus: CN III👀
3️⃣ 🔴 Nucleus: rubrospinal tract 🦾 (arm flexion)
4️⃣ Subst Nigra: basal ganglia relay (more complex than that)
5️⃣ Inf Colliculus

2/🧵
Read 24 tweets
Dec 26, 2022
4⃣ core brain networks (there are more): expanding the localizationist approach 🧠 🥅🕸️

#Neuro #Neuroanatomy #Neurology #EndNeurophobia

#Thread

1/🧵
1⃣ Default mode network

🥇 Endogenously mediated activities at rest
🥈 Self-referential and social cognitive processes,

🚫Not active during external goal-oriented processes

2/🧵
1⃣ Default mode network

Components

💠 Posterior cingulate cortex
💠 Medial prefrontal cortex
💠 Precuneus
💠 Inferior parietal and medial temporal cortices

3/🧵
Read 10 tweets
Dec 23, 2022
Sporadic Creutzfeldt-Jakob disease: clinical variants 🧠

🥸🤓

🐄

#CJD #Neurology #EndNeurophobia #Teaching

1/🧵

⏬One of my favorite 📚 about the topic (non medical and it focuses on familial forms)
Introduction 🚨

As seen in other types of neurodegenerative disorders (AD), the main localization of the pathological process will give rise to the main symptoms.

"It's not about pathophysiology, it's about localization." 🧠🤓🥸

2/
1⃣ Heidenhain Variant

Posterior localization, think 🤔

Visual disturbances first: 👀👁‍🗨👁️

3/
Read 10 tweets
Dec 16, 2022
Idiopathic intracranial hypertension: MRI features.

#Neurology #Neurotwitter #MRI #educational #Tweetorial

🪡

1/🧵
1⃣ Empty sella turcica (🏹)

🚨Flattened appearance of the pituitary gland against the floor of the sella turcica (🔼)

2/🧵
2⃣ Enlarged Meckel caves bilaterally, filled with CSF (🏹)

Related to Temporal Lobe Epilepsy? Maybe

3/🧵
Read 9 tweets
Dec 12, 2022
Dementia with Lewy Bodies:

Part 2️⃣ Biomarkers
🧠💊⚕️

#Neuro #Neurotwitter #Teaching #Education

#NotEverythingIsMemory

#Dementia

1/🧵
Introduction

What is a biomarker? 🏷🧪️

"A characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention." 🩸🧠

2/🧵
Introduction

What is the use of biomarkers? 🧠

Diagnostic tool🪓

Tool for staging the disease 🥼

Indicator of prognosis📡

Predic or monitor of clinical response to an intervention🚨

Remember: "tools"should aid clinicians, not be the source of all truth.

3/🧵
Read 14 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(