In 1961 the @ACSNews, @AHAScience, the National TB Association & @APHA sent a joint letter to @POTUS Kennedy asking to appoint a national commission to investigate the link between smoking and health, without wanting to threaten the freedom of the tobacco industry. 🧵
2/ He assigned this seemingly impossible task to his @SurgeonGeneral, Luther Terry. Terry appointed an expert advisory committee to summarize the links between smoking and lung cancer. Over 13 months they met for 9 sessions.

profiles.nlm.nih.gov/spotlight/nn/f…
3/ The 387 page report was released on January 11, 1964 and was one of largest cohorts ever analyzed by an epidemiological report. The truth was, people had already known about health risks of smoking for almost 15 years. It wasn’t interesting news anymore despite ongoing harm. Title: Smoking and Health: Report of the Advisory Committee
4/ In 1950, two major studies were published showing exactly this link - smoking causes lung cancer. But despite being in prominent medical journals, @JAMA_current & @bmj_latest, they were largely ignored by the media & the public.
jamanetwork.com/journals/jama/…

bmj.com/content/2/4682…
5/ No amount of compelling or rock solid evidence could sway public opinion. It was a battle science could not fight alone. The cycle of greed, human tragedy, habit, deception, and doubt in science, is just so depressingly familiar.
history.com/.amp/news/ciga… Ad for camels cigarettes.   “He's one of the busiest men i
6/ BUT the 1964 report on smoking & health had an impact on public attitudes and policy. It was also a catalyst for removing television advertisements. A survey from @GallupNews found that in 1958 only 44% of Americans believed smoking caused cancer, while 78% believed so by 1968
7/ In 1965, Congress required all cigarette packages distributed in the United States to carry a health warning, and since 1970 this warning is made in the name of the @SurgeonGeneral.

In 1969, cigarette advertising on television and radio was banned, effective September 1970. Photo of side of white/gold cigarette carton showing warning
8/ On the mantle of history you CAN be remembered as a man like Luther Terry.

Or you can be complicit in the continued inaction and poor policy choices that have resulted in the death & disability of millions of Americans.
9/ Can you imagine if @Surgeon_General embodied Luther Terry and compiled the extensive data on #SARSCOV2 infection & #COVID19 and the observed long term health effects of the heart, brain and other organs, informed the public & issued a formal statement of warning to the nation?
10/ When the pandemic began, I imagined creating a system of subcommittees by organ system or unique patient population (eg pregnancy) to issue guidelines in the context of discussions across disciplines. I still think that is how we will learn the most & best care for patients. Screen grab of mock website “The Nucleus” showing  diffe
11/ Listen to patients. Read the data - it *IS* out there. Protect yourself from infection and reinfection. What we DO know is already scary👇, but just as with SARS1 there are decades of damage we have yet to discover and understand. H/T @EricTopol @ahandvanish @LisaAMcCorkell
12/ @POTUS, @VP, @Surgeon_General, it is time to WARN the #American public about what infection and repeat infection with this virus really does.

How many more US citizens have to die or become disabled?

For our kids and grandkids,

We MUST try.

#COVID #SARSCoV2 #LongCOVID 😷 “SURGEON GENERAL'S WARNING: Smoking Causes Lung Cancer, He
13/ Below are just SOME of the papers that I have found most critical in understanding #COVID and #LongCOVID in particular,
but they are truly a drop in a literal OCEAN of existing literature showing the damage this virus can cause (obviously not complete/comprehensive)
17/ Mucosal vaccines have the potential to stop *infection* at the source not just reduce the severity/burden of disease after people are infected.

So grateful for the seemingly indefatigable @VirusesImmunity 🙏
18/ And historic work by so many patients, including:

How and Why Patients made Long COVID by @elisaperego78 & @felicitycallard
sciencedirect.com/science/articl…

Characterizing long COVID in an international cohort: 7 months of symptoms and their impact
doi.org/10.1016/j.ecli…

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Keep Current with Erin C. Sanders, MSN, WHNP-BC (She/Her)

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More from @ErinSandersNP

Jan 19
Put the label on some N95s and mail them to every American family. And start finally making kid size ones.

Issue public service announcements about cleaning the air. And how doing so improves health not just against #COVID, but allergens, pollution and other pathogens.
2/ Like someone with much better graphic design skills can make a mock up #American version USA99 (with 3M or something). Press an American Bald Eagle on the nose bridge (where the maple leaf is). Put the warning on the side. Give them to EVERYONE for FREE. Require in hospitals. Children’s CAN99 respirators from Canada made by vitacore Adult CAN99 respirators from Canada made by vitacore
3/ Then! Send each family a kit to make a corsi rosenthol box: 4xMERV13 filters, a box fan, duct tape. Takes 60 min or less to build, costs less than $30. Can reuse by adding new filters. Works for ALL air pollution: wildfire smoke, mold, pollen, dust, germs & #COVID.
Read 12 tweets
Nov 26, 2022
Progesterone, contraception & chronic disease

Dovetailing off MMPs, for menstruating people, I am curious if the expected hormonal fluctuation and necessary cyclical tissue breakdown could be associated with a higher risk for barrier permeability and pathogen translocation? Graphic representation of the menstrual cycle showing ovaria
2/ Furthermore, if progesterone “PRO-Gestation” is a hormone that is able to trigger (red arrow) or prohibit the cyclical ischemia and breakdown of the endometrium to support a pregnancy, could it do that for other mucosal barriers as well?
cc: @DrJenGunter @doctorjenn @acweyand Graphic representation of the menstrual cycle showing ovaria
3/ Some background: In a healthy menstrual cycle, the ovary makes multiple follicles. One follicle grows larger with the egg that will be released. After the egg is released by the follicle and out of the ovary, it travels down the fallopian tube to the uterus to implant. Schematic detailing the stages of mammalian folliculogenesis
Read 24 tweets
Oct 15, 2022
A core mission of mine has become deconstructing the false binary fallacy of clinician vs patient that is perpetuated by both sides.

And instead making space for the many clinicians & trainees who are also patients & bring hard earned patient wisdom to their practice & science🧵
2/ Being able to translate patient experience into the language of science, medicine and healthcare, and connect worlds of expertise has tremendous value.

These often painful experiences can enrich the care and wisdom we offer to others.

When you know better, do better ♥️
3/ On ableism and exclusion of disabled clinicians in healthcare:
Read 32 tweets
Jun 3, 2022
I have been *waiting* for this type of extensive autopsy study to be be performed since I first learned about #COVID19. 3/2020-3/2021
N=44 autopsies; Brains = 11
Great care taken to be performed within 24 hrs of death.
None vaccinated. Prior to variants.

cc: @drjudymelinek 🧠 Image
Alt text: figure shows viral RNA was detected in every brain structure/region they tested in deceased patients with #COVID19 (n=11)

Link to presentation: videocast.nih.gov/watch=45296?jw…
They have full body data on these 11 patients including the brain.

Photo 1: SARSCOV2 RNA by PCR
Photo 2: subgenomic RNA overlaid on #SARSCOV2 sgRNA
Photo 3: Demographics
Photo 4: Clinical Summary ImageImageImageImage
Read 27 tweets

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