Of 946 severe COVID patients age 50 and older with no previous dementia or memory complaints, ... 10.7% had long-term impairment that persisted at 1 year, according to Claudia Kimie Suemoto, MD, PhD, of the University of São Paulo Medical School in Brazil, and co-authors.
2/D
The Brasilian team defined severe COVID, including the presence of dyspnea, .. a blood oxygen saturation of 93% or less...
The study had several limitations, the researchers acknowledged. Participants came from early waves of the pandemic, before vaccines were available.
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Previous research in Wuhan, showed that the incidence of cognitive impairment 12 months after discharge was 12.45% for older COVID patients.
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More recently, a pooled analysis of nearly 1.3 million COVID-19 -- mostly in the U.S. Cognitive deficit, dementia, psychotic disorders, and epilepsy or seizures were increased at 6 months in adults 18-64 and remained elevated at the end of the 2-year follow-up period.
5/D
The US study was mentioned in Medpage in August 22.
Same author.
Post-COVID Neurologic, Psychiatric Symptoms May Persist for 2 Years
— Risk profiles, trajectories vary for children and adults medpagetoday.com/neurology/long…
6/D
We are in March of 2023
What are the more recent studies and efforts to follow up on cognitive impairement of older adults, adults of working age and kids ? #covid19#brain#postcovid#longcovid#Pasc
7/D
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"Ensuite, nous nous débarrassons également d'autres infections et obtenons un meilleur climat intérieur. Parmi les experts figurent à la fois le directeur général et l'ancien directeur professionnel de SSI."
"it likely that multi-tasking melatonin will provide multi-protection, maintaining its efficacy against the virus variants that are already emerging and will emerge" mdpi.com/2076-3921/10/7…
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"Melatonin is a systemic dealer that".."brings into play its cooperative triad, antioxidant, anti-inflammatory, and immune-stimulant backbone, to stop the infective cycle of SARS-CoV-2 or any other endogenous or exogenous threat.
2/
"In COVID-19, the corporal propagation of
SARS-CoV-2 involves an exacerbated oxidative activity and therefore the overproduction of great amounts of reactive oxygen and nitrogen species (RONS)."
3/
Hier le médecin à l'hopital ne percutait pas sur le #paxlovid. Aujourd'hui ils ont eu une réunion de service & il va regarder. Des interactions médicamenteuses & des contre-indications, mais j'espère que cela va le faire. #Antiviral sur #ordonnance #covid19
1/10
2/10
Au cas où je m'étais bien documentée et je mets les liens dans ce thread.
C'est à prendre dans les 5 jours, et même si les molécules ne sont pas nouvelles mais l'usage associé l'est donc il est intéressant d'être bien au courant avec son médecin.
3/10 #Paxlovid (PF-07321332/ritonavir) #France#EU#UE
Aperçu de Paxlovid et pourquoi il est autorisé dans l’Union européenne (UE)
European Medicines Agency
Worth reading again. The #Swisscheese model is a guide for our strategy to quell #covid19 & other pandemics (#monkeypox?)
No single intervention is perfect.
Each layer may have holes.
But the pile will provide.
Pick well your pile!